Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Errin, Johnson"'
Publikováno v:
Cell Reports: Methods, Vol 4, Iss 7, Pp 100814- (2024)
Summary: Inorganic polyphosphate (polyP) is a ubiquitous polymer that controls fundamental processes. To overcome the absence of a genetically tractable mammalian model, we developed an inducible mammalian cell line expressing Escherichia coli polyph
Externí odkaz:
https://doaj.org/article/ebb125e0886b4b089aeb25f8387d0827
Autor:
Eboni M. V. Bucknor, Errin Johnson, Stephanie Efthymiou, Javeria R. Alvi, Tipu Sultan, Henry Houlden, Reza Maroofian, Ehsan G. Karimiani, Mattéa J. Finelli, Peter L. Oliver
Publikováno v:
Antioxidants, Vol 13, Iss 6, p 685 (2024)
Loss-of-function mutations in the TLDc family of proteins cause a range of severe childhood-onset neurological disorders with common clinical features that include cerebellar neurodegeneration, ataxia and epilepsy. Of these proteins, oxidation resist
Externí odkaz:
https://doaj.org/article/d764a9d44f664403965dbb7bfe8416aa
Autor:
Pablo F. Céspedes, Ashwin Jainarayanan, Lola Fernández-Messina, Salvatore Valvo, David G. Saliba, Elke Kurz, Audun Kvalvaag, Lina Chen, Charity Ganskow, Huw Colin-York, Marco Fritzsche, Yanchun Peng, Tao Dong, Errin Johnson, Jesús A. Siller-Farfán, Omer Dushek, Erdinc Sezgin, Ben Peacock, Alice Law, Dimitri Aubert, Simon Engledow, Moustafa Attar, Svenja Hester, Roman Fischer, Francisco Sánchez-Madrid, Michael L. Dustin
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
T cells communicate with antigen-presenting cells (APC) via the signaling crosstalk at the immunological synapse (IS). Here the authors use bead-supported lipid bilayers as synthetic APCs to find that trans-synaptic vesicles produced by T cells in th
Externí odkaz:
https://doaj.org/article/bf36826120af49d29b1ddc87ef30f8f6
Autor:
Alun Vaughan-Jackson, Szymon Stodolak, Kourosh H. Ebrahimi, Errin Johnson, Paul K. Reardon, Maeva Dupont, Shengpan Zhang, James S. O. McCullagh, William S. James
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Macrophage distribution density is tightly regulated within the body, yet the importance of macrophage crowding during in vitro culture is largely unstudied. Using a human induced pluripotent stem cell (iPSC)-derived macrophage model of tissue reside
Externí odkaz:
https://doaj.org/article/9f8886a412c84bcbb1ed246d71b4d3a9
Autor:
Daan Paget, Antonio Checa, Benedikt Zöhrer, Raphael Heilig, Mayooran Shanmuganathan, Raman Dhaliwal, Errin Johnson, Maléne Møller Jørgensen, Rikke Bæk, Oxford Acute Myocardial Infarction Study (OxAMI), Craig E. Wheelock, Keith M. Channon, Roman Fischer, Daniel C. Anthony, Robin P. Choudhury, Naveed Akbar
Publikováno v:
Journal of Extracellular Biology, Vol 1, Iss 11, Pp n/a-n/a (2022)
Abstract Plasma extracellular vesicle (EV) number and composition are altered following myocardial infarction (MI), but to properly understand the significance of these changes it is essential to appreciate how the different isolation methods affect
Externí odkaz:
https://doaj.org/article/44d6039664fe46df920cb4c07f32c95f
Autor:
Caroline Scott, Damien J. Downes, Jill M. Brown, Robert Beagrie, Aude-Anais Olijnik, Matthew Gosden, Ron Schwessinger, Christopher A. Fisher, Anna Rose, David J.P Ferguson, Errin Johnson, Quentin A. Hill, Steven Okoli, Raffaele Renella, Kate Ryan, Marjorie Brand, Jim Hughes, Noemi B.A. Roy, Douglas R. Higgs, Christian Babbs, Veronica J. Buckle
Publikováno v:
Haematologica, Vol 106, Iss 11 (2020)
The investigation of inherited disorders of erythropoiesis has elucidated many of the principles underlying the production of normal red blood cells and how this is perturbed in human disease. Congenital dyserythropoietic anemia type 1 (CDA-I) is a r
Externí odkaz:
https://doaj.org/article/0fcc0bfec45f409db5985ffd8cff4142
Publikováno v:
PLoS Pathogens, Vol 16, Iss 3, p e1008372 (2020)
It is increasingly being recognised that the interplay between commensal and pathogenic bacteria can dictate the outcome of infection. Consequently, there is a need to understand how commensals interact with their human host and influence pathogen be
Externí odkaz:
https://doaj.org/article/3c5f8ce28d814eac934e4a4d11f68d78
Autor:
Rebecca A. Russell, Jakub Chojnacki, Daniel M. Jones, Errin Johnson, Thao Do, Christian Eggeling, Sergi Padilla-Parra, Quentin J. Sattentau
Publikováno v:
Cell Reports, Vol 18, Iss 6, Pp 1473-1483 (2017)
HIV-1 disseminates to diverse tissues and establishes long-lived viral reservoirs. These reservoirs include the CNS, in which macrophage-lineage cells, and as suggested by many studies, astrocytes, may be infected. Here, we have investigated astrocyt
Externí odkaz:
https://doaj.org/article/0d0c0eeca1924b21b67d63118df483f9
Autor:
Lucy M. Collinson, Carles Bosch, Anwen Bullen, Jemima J. Burden, Raffaella Carzaniga, Cheng Cheng, Michele C. Darrow, Georgina Fletcher, Errin Johnson, Kedar Narayan, Christopher J. Peddie, Martyn Winn, Charles Wood, Ardan Patwardhan, Gerard J. Kleywegt, Paul Verkade
Publikováno v:
Collinson, L M, Bosch, C, Bullen, A, Burden, J J, Carzaniga, R, Cheng, C, Darrow, M C, Fletcher, G, Johnson, E, Narayan, K, Peddie, C J, Winn, M, Wood, C, Patwardhan, A, Kleywegt, G J & Verkade, P 2023, ' Volume EM : a quiet revolution takes shape ', Nature Methods, vol. 20, no. 6, pp. 777-782 . https://doi.org/10.1038/s41592-023-01861-8
Volume electron microscopy (vEM) is a group of techniques that reveal the 3D ultrastructure of cells and tissues through continuous depths of at least 1 micrometer. A burgeoning grassroots community effort is fast building the profile and revealing t
Publikováno v:
PLoS Genetics, Vol 14, Iss 2, p e1007198 (2018)
Pericentrin is a conserved centrosomal protein whose dysfunction has been linked to several human diseases. It has been implicated in many aspects of centrosome and cilia function, but its precise role is unclear. Here, we examine Drosophila Pericent
Externí odkaz:
https://doaj.org/article/106c8d8a4c2d4a6da9ab14bc90f30aee