Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Erquan Zhang"'
Autor:
Jane Chanda Kabwe, Hirofumi Sawada, Yoshihide Mitani, Hironori Oshita, Naoki Tsuboya, Erquan Zhang, Junko Maruyama, Yoshiki Miyasaka, Hideyoshi Ko, Kazunobu Oya, Hiromasa Ito, Noriko Yodoya, Shoichiro Otsuki, Hiroyuki Ohashi, Ryuji Okamoto, Kaoru Dohi, Yuhei Nishimura, Tomoji Mashimo, Masahiro Hirayama, Kazuo Maruyama
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-22 (2022)
Abstract Background Patients with pulmonary arterial hypertension (PAH) carrying bone morphogenetic protein receptor type 2 (Bmpr2) mutations present earlier with severe hemodynamic compromise and have poorer survival outcomes than those without muta
Externí odkaz:
https://doaj.org/article/92a8518c4a4b459c8d7fad7b798a5a72
Autor:
Masako Kawai, Erquan Zhang, Jane Chanda Kabwe, Amphone Okada, Junko Maruyama, Hirofumi Sawada, Kazuo Maruyama
Publikováno v:
BMC Pulmonary Medicine, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Background Rats with chronic hypoxia-induced non-inflammatory pulmonary hypertension (PH) are resistant to ventilator-induced lung injury. We investigated the effect of high tidal volume ventilation in another model of PH, monocrotaline (MCT
Externí odkaz:
https://doaj.org/article/1e537076e92a4f41bb8ab98a649f7107
Autor:
Toshikazu Ito, Erquan Zhang, Ayaka Omori, Jane Kabwe, Masako Kawai, Junko Maruyama, Amphone Okada, Ayumu Yokochi, Hirofumi Sawada, Yoshihide Mitani, Kazuo Maruyama
Publikováno v:
BMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-17 (2021)
Abstract Background Preventing pulmonary vascular remodeling is a key strategy for pulmonary hypertension (PH). Causes of PH include pulmonary vasoconstriction and inflammation. This study aimed to determine whether cilostazol (CLZ), a phosphodiester
Externí odkaz:
https://doaj.org/article/c584309c6a5d45aaa3503139a0958425
Autor:
Taichi Kato, Yoshihide Mitani, Masahiro Masuya, Junko Maruyama, Hirofumi Sawada, Hiroyuki Ohashi, Yukiko Ikeyama, Shoichiro Otsuki, Noriko Yodoya, Tsutomu Shinohara, Eri Miyata, Erquan Zhang, Naoyuki Katayama, Hideto Shimpo, Kazuo Maruyama, Yoshihiro Komada, Masahiro Hirayama
Publikováno v:
Pulmonary Circulation, Vol 10 (2020)
The aim of this study was to investigate whether a dual endothelin receptor antagonist bosentan modulates the kinetics of bone marrow-derived stem cells in inhibiting the development of pulmonary hypertension. Bone marrow chimeric mice, transplanted
Externí odkaz:
https://doaj.org/article/bf44ce81bd394bbc85490e0ec709ec61
Autor:
Hiroki Shoji, Yoko Yoshida, Takayuki Jujo Sanada, Akira Naito, Junko Maruyama, Erquan Zhang, Kengo Sumi, Seiichiro Sakao, Kazuo Maruyama, Hiroyoshi Hidaka, Koichiro Tatsumi
Publikováno v:
Cells, Vol 11, Iss 1, p 66 (2021)
Pulmonary arterial hypertension (PAH) is characterized by elevated pulmonary arterial pressure and right heart failure. Selective pulmonary vasodilators have improved the prognosis of PAH; however, they are not able to reverse pulmonary vascular remo
Externí odkaz:
https://doaj.org/article/c606b099d8604ba3880cb1ddc26466da
Autor:
Shoichiro Otsuki, Hirofumi Sawada, Noriko Yodoya, Tsutomu Shinohara, Taichi Kato, Hiroyuki Ohashi, Erquan Zhang, Kyoko Imanaka-Yoshida, Hideto Shimpo, Kazuo Maruyama, Yoshihiro Komada, Yoshihide Mitani
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0118655 (2015)
We tested the hypothesis that phenotypically modulated smooth muscle cells (SMCs) and related inflammation are associated with the progression of experimental occlusive pulmonary vascular disease (PVD). Occlusive PVD was induced by combined exposure
Externí odkaz:
https://doaj.org/article/70fdf1f663f54843803962e26392450f
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109522- (2024)
Summary: Individuals within the amyotrophic lateral sclerosis and frontotemporal dementia disease spectrum (ALS/FTD) often experience disruptive mental behaviors and sleep-wake disturbances. The hallmark of ALS/FTD is the pathological involvement of
Externí odkaz:
https://doaj.org/article/e03667544a5c4398ba66337e1281f186
Autor:
Rui Zhou, Guodong Wang, Qi Li, Fanxi Meng, Can Liu, Rui Gan, Dapeng Ju, Meimei Liao, Junjie Xu, Di Sang, Xue Gao, Shuang Zhou, Kejia Wu, Quanzhi Sun, Ying Guo, Chongyang Wu, Zhiyu Chen, Lin Chen, Bihan Shi, Haiyan Wang, Xia Wang, Huaiye Li, Tao Cai, Bin Li, Fengchao Wang, Hiromasa Funato, Masashi Yanagisawa, Eric Erquan Zhang, Qinghua Liu
Publikováno v:
Nature. 612:519-527
In mice and humans, sleep quantity is governed by genetic factors and exhibits age-dependent variation
Autor:
Ziqing Yu, Erquan Zhang
Publikováno v:
Communications in Information and Systems. 22:401-427
Autor:
Jane Kabwe, Hirofumi Sawada, Masako Kawai, Kazuo Maruyama, Ayumu Yokochi, Yoshihide Mitani, Amphone Okada, Ayaka Omori, Toshikazu Ito, Junko Maruyama, Erquan Zhang
Publikováno v:
BMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-17 (2021)
BMC Pulmonary Medicine
BMC Pulmonary Medicine
Background Preventing pulmonary vascular remodeling is a key strategy for pulmonary hypertension (PH). Causes of PH include pulmonary vasoconstriction and inflammation. This study aimed to determine whether cilostazol (CLZ), a phosphodiesterase-3 inh