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Publikováno v:
Hungarian Medical Journal / Orvosi Hetilap; 2024, Vol. 165 Issue 29, p1130-1134, 5p
Publikováno v:
European Neuropsychopharmacology. 27:S739-S740
Autor:
James H. Naismith, Changjiang Dong, Eugenio P. Patallo, Silvana Flecks, Xiaofeng Zhu, Karl-Heinz van Pée, Alexander Schneider, Aliz J. Ernyei, Gotthard Seifert
Publikováno v:
Angewandte Chemie International Edition. 47:9533-9536
(Chemical Equation Presented) It takes two: Both a lysine and a glutamate residue in the active site of tryptophan halogenase are essential for its chlorination activity. A mechanism for the regioselective enzymatic chlorination of tryptophan involvi
Autor:
Gotthard Seifert, Changjiang Dong, Silvana Flecks, Karl-Heinz van Pée, Xiaofeng Zhu, Eugenio P. Patallo, Aliz J. Ernyei, James H. Naismith, Alexander Schneider
Publikováno v:
Angewandte Chemie. 120:9676-9679
Publikováno v:
Chemie Ingenieur Technik. 80:783-794
Autor:
Aliz J. Ernyei, Changjiang Dong, James H. Naismith, Catharina Hatscher, Andrea Kunzendorf, Julia Rumpf, Corina Seibold, Karl-Heinz van Pée, Helge Schnerr, Tobias Wage
Publikováno v:
Biocatalysis and Biotransformation. 24:401-408
Regioselective halogenation of electron rich substrates is catalysed by flavin-dependent halogenases. Thienodolin produced by Streptomyces albogriseolus contains a chlorine atom in the 6-position of the indole ring system and is believed to be derive
Publikováno v:
European Neuropsychopharmacology. 26:S341-S342
Publikováno v:
European Neuropsychopharmacology. 26:S336
Publikováno v:
Mikrochimica Acta. 118:113-121
The aim of our experiments was to investigate the possible elemental concentration changes in brain tumours (glioblastoma multiforme). Our project also incorporated the determination of the regional distribution of elements in normal human brains. 17