Zobrazeno 1 - 10
of 331
pro vyhledávání: '"Ernst Mutschler"'
Autor:
Jurgen Wess, Celine Valant, Andrew B. Tobin, David Thal, Roy D. Schwarz, Neil M. Nathanson, Ernst Mutschler, Fred Mitchelson, Chris Langmead, Günter Lambrecht, Heinz J. Kilbinger, Rudolf Hammer, Christian C. Felder, Frederick Ehlert, Richard M. Eglen, Arthur Christopoulos, R.A. John Challiss, Noel J. Buckley, David A. Brown, Sophie Bradley, Nigel J. M. Birdsall
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2023
Muscarinic acetylcholine receptors (mAChRs) (nomenclature as agreed by the NC-IUPHAR Subcommittee on Muscarinic Acetylcholine Receptors [53]) are activated by the endogenous agonist acetylcholine. All five (M1-M5) mAChRs are ubiquitously expressed in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2393b817766271e25eebe9983a497ad3
https://doi.org/10.2218/gtopdb/f2/2023.1
https://doi.org/10.2218/gtopdb/f2/2023.1
Autor:
Neil M. Nathanson, Jürgen Wess, Rudolf Hammer, R. A. John Challiss, Richard M. Eglen, Fred Mitchelson, David Brown, Sophie J. Bradley, Celine Valant, Heinz Kilbinger, Chris Langmead, Frederick J. Ehlert, Andrew B. Tobin, Noel J. Buckley, Ernst Mutschler, Günter Lambrecht, Arthur Christopoulos, David M. Thal, Roy D. Schwarz, Nigel J. M. Birdsall, Christian C. Felder
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2021
Muscarinic acetylcholine receptors (mAChRs) (nomenclature as agreed by the NC-IUPHAR Subcommittee on Muscarinic Acetylcholine Receptors [50]) are activated by the endogenous agonist acetylcholine. All five (M1-M5) mAChRs are ubiquitously expressed in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21748271f1e349fb133f34951200f47b
https://doi.org/10.2218/gtopdb/f2/2021.3
https://doi.org/10.2218/gtopdb/f2/2021.3
Autor:
Frederick J. Ehlert, Nigel J. M. Birdsall, Ernst Mutschler, Heinz Kilbinger, Günter Lambrecht, Neil M. Nathanson, Roy D. Schwarz, Sophie J. Bradley, Richard M. Eglen, Christian C. Felder, David M. Thal, R. A. John Challiss, Rudolf Hammer, Andrew B. Tobin, Jürgen Wess, Arthur Christopoulos, Celine Valant, Noel J. Buckley, Fred Mitchelson, David Brown, Chris Langmead
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2021
Muscarinic acetylcholine receptors (mAChRs) (nomenclature as agreed by the NC-IUPHAR Subcommittee on Muscarinic Acetylcholine Receptors [50]) are activated by the endogenous agonist acetylcholine. All five (M1-M5) mAChRs are ubiquitously expressed in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8bba16c5815dfeddf5c98ecc587ad10
https://doi.org/10.2218/gtopdb/f2/2021.2
https://doi.org/10.2218/gtopdb/f2/2021.2
Autor:
Celine Valant, Fred Mitchelson, Noel J. Buckley, David Brown, Neil M. Nathanson, Roy D. Schwarz, Nigel J. M. Birdsall, Christian C. Felder, Rudolf Hammer, Chris Langmead, Arthur Christopoulos, Günter Lambrecht, Frederick J. Ehlert, Richard M. Eglen, Jürgen Wess, Sophie J. Bradley, Ernst Mutschler, Heinz Kilbinger, Andrew B. Tobin, R. A. John Challiss
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2019
Muscarinic acetylcholine receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Muscarinic Acetylcholine Receptors [45]) are GPCRs of the Class A, rhodopsin-like family where the endogenous agonist is acetylcholine. In addition to the age
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82759d508ecb75f5dfc898b765bb28a1
https://doi.org/10.2218/gtopdb/f2/2019.4
https://doi.org/10.2218/gtopdb/f2/2019.4
Autor:
Ulrich Moser, Gerd Dannhardt, Ernst Mutschler, Caren Hildebrandt, Günter Lambrecht, Vincenzo Tumiatti, Jahn Wehrle
Publikováno v:
Arzneimittelforschung. 50:11-15
A series of new analogues of the arecaidine propargyl ester (CAS 35516-99-5, APE, 1a) with alcohols consisting of 4 or 5 carbon atoms were investigated at muscarinic receptor subtypes. The muscarinic activity of the quaternary and tertiary salts of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b826ad467d41fc6e8b23d1addfb38bf
https://doi.org/10.1055/s-0031-1300157
https://doi.org/10.1055/s-0031-1300157
Autor:
H. Knauf, Ernst Mutschler
Publikováno v:
Arzneimittelforschung. 55:1-14
Xipamid (CAS 14293-44-8) weist strukturelle Analogien sowohl zu den Thiaziden als auch zu Schleifendiuretika auf. Da dieses Diuretikum - im Unterschied zu den Thiaziden - nach fruheren Untersuchungen nicht die glomerulare Filtrationsrate (GFR) beeint
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8075174481fa63146dd0bebaaea0ed8
https://doi.org/10.1055/s-0031-1296819
https://doi.org/10.1055/s-0031-1296819
Autor:
Ernst Mutschler, H. Knauf
Publikováno v:
Pharmazie in unserer Zeit. 35:302-309
Diuretika als harntreibende Arzneistoffe wurden zunachst klinisch-pharmakologisch nach dem Ausmas der Diuresesteigerung und der Dosis-Abhangigkeit ihrer Wirkung eingeteilt. Demgemas unterschied man High-ceiling-von Low-ceiling-Diuretika, wobei der Be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24759c0bc18fbb5700c8b8ea3a12b060
https://doi.org/10.1002/pauz.200600177
https://doi.org/10.1002/pauz.200600177
Autor:
Ernst Mutschler, H. Knauf
Publikováno v:
Pharmazie in unserer Zeit. 35:334-340
Die nach klinischer Indikation gewahlte Kombination verschiedener Diuretika-Klassen mit konsekutiver Hemmung verschiedener tubularer Transportmechanismen wird als “sequenzielle Nephronblockade” bezeichnet. Wie pharmakologische Studien belegen, wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c76013172ac69aa0f575dbe736bac0c2
https://doi.org/10.1002/pauz.200600180
https://doi.org/10.1002/pauz.200600180
Autor:
Ernst Mutschler
Publikováno v:
Pharmazie in Unserer Zeit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::773aa8e3836619c27c60a87779e85ca1
https://doi.org/10.1002/pauz.200490129
https://doi.org/10.1002/pauz.200490129