Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Ernst M. App"'
Autor:
Ulrich Baumann, Malcolm King, Ernst M App, Shusheng Tai, Armin König, Julia J Fischer, Torsten Zimmermann, Wolfgang Sextro, Horst von der Hardt
Publikováno v:
Canadian Respiratory Journal, Vol 11, Iss 2, Pp 151-155 (2004)
BACKGROUND: Following reports on the treatment of diffuse panbronchiolitis (DPB), recent studies demonstrate that long term therapy with azithromycin (AZM) is effective in cystic fibrosis (CF) patients. However, the underlying mechanisms remain uncer
Externí odkaz:
https://doaj.org/article/62b7859d9b9f4de59fc89ceb92d14b50
Autor:
Shusheng Tai, Ulrich Baumann, Horst von der Hardt, Julia J Fischer, Ernst M. App, Wolfgang Sextro, Malcolm King, Armin König, Torsten Zimmermann
Publikováno v:
Canadian Respiratory Journal, Vol 11, Iss 2, Pp 151-155 (2004)
BACKGROUND:Following reports on the treatment of diffuse panbronchiolitis (DPB), recent studies demonstrate that long term therapy with azithromycin (AZM) is effective in cystic fibrosis (CF) patients. However, the underlying mechanisms remain uncert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::850610851443d8ff6a07e188b118ae47
https://doaj.org/article/62b7859d9b9f4de59fc89ceb92d14b50
https://doaj.org/article/62b7859d9b9f4de59fc89ceb92d14b50
Autor:
Rebecca S, Lam, Ernst M, App, Drew, Nahirney, Artur J, Szkotak, Maria A, Vieira-Coelho, Malcolm, King, Marek, Duszyk
Publikováno v:
The Journal of Physiology. 548:475-484
Previous studies have shown that alpha2 adrenoceptor (alpha2AR) agonists inhibit electrolyte secretion in colonic epithelia, but little is known about the molecular mechanisms involved in this process. In this study we examined the effect of alpha2AR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::903dc7bc6aaf8a996351babae073d3b5
https://doi.org/10.1113/jphysiol.2002.036806
https://doi.org/10.1113/jphysiol.2002.036806
Autor:
P. Maes, Ernst M. App, M. Coffiner, Bruce K. Rubin, R. P. Tomkiewicz, G. T. De Sanctis, Malcolm King
Publikováno v:
Pulmonary Pharmacology. 8:259-265
A newly synthesized mucolytic agent, N-acetylcysteine L-lysinate (Nacystelyn) was studied. Tracheal mucus velocity (TMV), transepithelial potential difference (PD), rheological properties, and ion content of collected airway secretions were evaluated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d58285150b962ce45203cb8277f2390
https://doi.org/10.1006/pulp.1995.1035
https://doi.org/10.1006/pulp.1995.1035
Publikováno v:
Scopus-Elsevier
N-acetylcysteine L-lysinate Nacystelyn (L-NAC) is a newly synthesized mucolytic agent, of which the action in vivo has not been well defined. In six healthy mongrel dogs, the rheological properties of mucus, its mucociliary and cough clearability, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8167c6dba84b240b485e02c525ca20a8
https://doi.org/10.1183/09031936.94.07010081
https://doi.org/10.1183/09031936.94.07010081
Autor:
Richard C Boucher, Oscar Ramirez, Malcolm King, Michael R Knowles, N. Church, J. G. Zayas, Robert P. Tomkiewicz, Ernst M. App
Publikováno v:
American Review of Respiratory Disease. 148:1002-1007
Amiloride inhalation as treatment for cystic fibrosis (CF) lung disease has been shown in independent studies to increase mucus clearance by ciliary and/or cough action and to retard the decline in lung function. It is hypothesized that amiloride the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a656a3d1e0235d0464e52cb14500f813
https://doi.org/10.1164/ajrccm/148.4_pt_1.1002
https://doi.org/10.1164/ajrccm/148.4_pt_1.1002
Autor:
Ernst M. App, Malcolm King
Publikováno v:
Biorheology. 27:515-526
The transepithelial potential difference (PD) value represents an integral of ion fluxes across the epithelium, and relates to the regulation of airway fluid. We studied six healthy two day old husky puppies for their tracheal mucus rheology and bioe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee8b02fd46004ce293c8231c5362b402
https://doi.org/10.3233/bir-1990-273-430
https://doi.org/10.3233/bir-1990-273-430
Publikováno v:
Scopus-Elsevier
Cystic fibrosis (CF) is the most common inherited fatal disorder among Caucasians. Bronchial mucus in CF contains more potassium and less sodium, which may be due to increased sodium absorption, resulting in a reduced airway water content. We studied
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34a2bf4d3966b3f4005996945624c1ca
https://doi.org/10.1164/ajrccm/141.3.605
https://doi.org/10.1164/ajrccm/141.3.605
Stellenwert der Mukusclearance für das Bronchialsystem — Pathophysiologie und therapeutische Ansätze
Autor:
Ernst M. App
Publikováno v:
Entzündliche Erkrankungen des Bronchialsystems ISBN: 9783540672333
Die Schleimhaut des Respirationstraktes steht unmittelbar mit der Umwelt in Kontakt. Zur Abwehr exogener Noxen stehen physikalische, zellulare und biochemische Mechanismen zur Verfugung. Physikalische Abwehrmechanismen (Mukusclearance) werden uber Mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e031aafdf5d032925761037297a1ddfe
https://doi.org/10.1007/978-3-642-59770-1_2
https://doi.org/10.1007/978-3-642-59770-1_2
Autor:
Oscar E. Ramirez, Hani Shennib, Dao M. Nguyen, Malcolm King, Robert P. Tomkiewicz, Ernst M. App
Publikováno v:
Chest. 107(1)
Impaired mucociliary function following lung transplantation has been reported in several human and animal studies. This could be a result of altered ciliary function or mucus properties or both. We assessed airway epithelial function by means of tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::672fbda11407c59c20dd21b48a76ba4e
https://pubmed.ncbi.nlm.nih.gov/7813288
https://pubmed.ncbi.nlm.nih.gov/7813288