Zobrazeno 1 - 10
of 151
pro vyhledávání: '"Ernst Knobil"'
Autor:
Ernst Knobil
Publikováno v:
Physiology. 14:1-11
Being selected a Cannon lecturer by the American Physiological Society is a singular honor under any circumstances, but a particularly poignant one for me because of my origins in Cannon’s old Department at the Harvard Medical School. In fact, when
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5423e750eaccae8768e764d313eacb92
https://doi.org/10.1152/physiologyonline.1999.14.1.1
https://doi.org/10.1152/physiologyonline.1999.14.1.1
Autor:
Martin A. Connaughton, J. Hotchkiss, Tamás Ördög, Ming Dao Chen, Ernst Knobil, Jason R. Goldsmith
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 83:4047-4053
In women and rhesus monkeys, both the negative and positive feedback actions of estradiol (E2) on gonadotropin secretion (inhibition followed by a surge) can be exerted directly at the level of the pituitary gland. We have tested the hypothesis that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba456c36fc213333aa9cb987f1caeb02
https://doi.org/10.1210/jcem.83.11.5230
https://doi.org/10.1210/jcem.83.11.5230
Autor:
Ernst Knobil, Tamás Ördög, J. Hotchkiss, Kevin T. O'Byrne, Martin A. Connaughton, Jason R. Goldsmith, Ming Dao Chen
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 274:E665-E676
The relative roles of infant suckling and of maternal prolactin (PRL) secretion in lactational anovulation were studied in ovary-intact and ovariectomized rhesus monkeys nursing young that had been removed from their natural mothers. Hypothalamic gon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c0ee94025bce4f69d3e859fd679be1b
https://doi.org/10.1152/ajpendo.1998.274.4.e665
https://doi.org/10.1152/ajpendo.1998.274.4.e665
Autor:
Ernst Knobil
Publikováno v:
Academic Medicine. 71:871-5
The contraction of employment opportunities for scientists and engineers has initiated debate about the nature and aims of graduate education. The course of study leading to the PhD degree is seen as being too long, too focused on a small, circumscri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64f1893c27fe2b8d4c61119bca80e6da
https://doi.org/10.1097/00001888-199608000-00014
https://doi.org/10.1097/00001888-199608000-00014
Ambient light modifies gonadotropin-releasing hormone pulse generator frequency in the rhesus monkey
Autor:
J. Hotchkiss, Jean-Christophe Thalabard, S. E. Chiappini, Kevin T. O'Byrne, Ming-Dao Chen, Ernst Knobil
Publikováno v:
Endocrinology. 133:1520-1524
In the course of previous studies using continuous monitoring of the electrophysiological correlates of GnRH pulse generator activity, characterized by episodic increases in hypothalamic multiunit electrical activity (MUA volley), it was noticed that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00c054cecd123fa72bac7355f4df3571
https://doi.org/10.1210/endo.133.4.8404590
https://doi.org/10.1210/endo.133.4.8404590
Autor:
Jean-Christophe Thalabard, Peter M. Grosser, Cynthia L. Williams, J. Hotchkiss, Kevin T. O'Byrne, Ernst Knobil
Publikováno v:
Neuroendocrinology. 57:115-119
In the ovariectomized rhesus monkey, estradiol (E2) markedly reduces the frequency of the GnRH pulse generator as monitored by LH pulse frequency and the concurrent changes in hypothalamic electrical activity, an action mimicked by morphine. In addit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e489609ef96dd3c070b2bb2de2d8464d
https://doi.org/10.1159/000126349
https://doi.org/10.1159/000126349
Autor:
Ernst Knobil, Ming-Dao Chen, Cynthia L. Williams, Masugi Nishihara, Kevin T. O'Byrne, J. Hotchkiss, Jean-Christophe Thalabard
Publikováno v:
Neuroendocrinology. 57:588-592
The activity of the GnRH pulse generator in the rhesus monkey is associated with abrupt increases in multiunit electrical activity (MUA) volleys recorded from the mediobasal hypothalamus that precede each pulse of LH in the peripheral circulation. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d266985fd1493742a1948d4affc34c9
https://doi.org/10.1159/000126411
https://doi.org/10.1159/000126411
Autor:
Ming-Dao Chen, Richard C. Wilson, Peter M. Grosser, Jean-Christophe Thalabard, Kevin T. O'Byrne, Cynthia L. Williams, D. Ladendorf, J. Hotchkiss, Ernst Knobil
Publikováno v:
Endocrinology. 129:1207-1214
Continuous monitoring of the electrophysiological manifestations of GnRH pulse generator activity was achieved by radiotelemetry throughout the menstrual cycles of unrestrained rhesus monkeys. The characteristic increases in hypothalamic multiunit ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0adfa261183c2ca4605b0966e152fb79
https://doi.org/10.1210/endo-129-3-1207
https://doi.org/10.1210/endo-129-3-1207
Autor:
Ernst Knobil
Publikováno v:
American Journal of Obstetrics and Gynecology. 163:1721-1727
The notion of an oscillator or signal generator in the central nervous system that controls the rhythmic release of GnRH and, thereby, the pulsatile secretion of the gonadotropic hormones, originated in the finding of strikingly abrupt and rhythmic f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d82bb6d4ac1cd051e6e1578a9aefeab
https://doi.org/10.1016/0002-9378(90)91435-f
https://doi.org/10.1016/0002-9378(90)91435-f