Spectral Imaging of Multi-Color Chromogenic Dyes in Pathological Specimens

Autor: Merryn V. E. Macville, Jeroen A. W. M. Van der Laak, Ernst J. M. Speel, Nir Katzir, Yuval Garini, Dirk Soenksen, George McNamara, Peter C. M. de Wilde, Antonius G. J. M. Hanselaar, Anton H.N. Hopman, Thomas Ried

Publikováno v: Analytical Cellular Pathology, Vol 22, Iss 3, Pp 133-142 (2001)

We have investigated the use of spectral imaging for multi‐color analysis of permanent cytochemical dyes and enzyme precipitates on cytopathological specimens. Spectral imaging is based on Fourier‐transform spectroscopy and digital imaging. A pix

Externí odkaz: https://doaj.org/article/633c5c0aaf804a53a969b100c37fc83e

Gene expression profiling of pulmonary neuroendocrine neoplasms: a comprehensive overview

Autor: Frans C. S. Ramaekers, Ernst J. M. Speel, Dorian R.A. Swarts

Publikováno v: Cancer Treatment Communications, 4, 148-160. Elsevier Ltd

Neuroendocrine neoplasms (NENs) of the lung comprise a heterogeneous group, including small cell lung cancer (SCLC), large cell neuroendocrine carcinoma and pulmonary carcinoids. To unravel their molecular biology, microarray studies have been conduc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94f48473915db3f495da0f55d06103d0
https://doi.org/10.1016/j.ctrc.2015.09.002

Limited additive value of the Ki-67 proliferative index on patient survival in World Health Organization-classified pulmonary carcinoids

Autor: Stefan Seidl, Ernst J. M. Speel, Dorian R.A. Swarts, Marco Volante, Sandra M.H. Claessen, Frans C. S. Ramaekers, Martina Rudelius, Jack P.M. Cleutjens

Publikováno v: Histopathology, 70(3), 412-422. Wiley-Blackwell
Histopathology, 70(3), 412-422. Wiley
Swarts, D R A, Rudelius, M, Claessen, S M H, Cleutjens, J P, Seidl, S, Volante, M, Ramaekers, F C S & Speel, E J M 2017, ' Limited additive value of the Ki-67 proliferative index on patient survival in World Health Organization-classified pulmonary carcinoids ', Histopathology, vol. 70, no. 3, pp. 412-422 . https://doi.org/10.1111/his.13096

Aims: Currently pulmonary carcinoids are separated into typical and atypical based on mitotic count and presence of necrosis, according to the World Health Organization. At variance with gastroenteropancreatic neuroendocrine tumours, which are graded

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5306b59e35f65c6126d1063095a30217
https://research.vumc.nl/en/publications/4944506a-d1a7-4d18-897a-41d7d4a43ed7

Gain of chromosome 8q is a frequent finding in pleuropulmonary blastoma

Autor: Christina A. Hulsbergen-van de Kaa, Leen van Leuven, Max M. van Noesel, Ernst J. M. Speel, Ronald R. de Krijger, Sandra M.H. Claessen, Ad J M van Unnik, Frieda van der Ham

Publikováno v: Modern Pathology, 20, 11, pp. 1191-9
Modern Pathology, 20, 1191-9
Modern Pathology, 20, 1191-1199. Nature Publishing Group

Contains fulltext : 53430.pdf (Publisher’s version ) (Closed access) Pleuropulmonary blastomas are rare malignant intrathoracic tumors of early childhood. They appear as a pulmonary- and/or pleural-based mass and their pathogenesis and relationship

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b639c6cca40f41a0fd2ce01e96ec6a2
https://doi.org/10.1038/modpathol.3800953

Role of human papillomavirus in the development of head and neck squamous cell carcinomas

Autor: Ernst J. M. Speel, Johannes J. Manni, Harriët C. Hafkamp

Publikováno v: Acta Oto-Laryngologica. 124:520-526

To review the literature on the role of oncogenic human papillomaviruses (HPVs) in the carcinogenesis of the head and neck mucosa.Molecular and epidemiological studies concerning the high-risk HPV types and their role in carcinogenesis in the head an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bea0438bd4f17320e68634c38b062f9e
https://doi.org/10.1080/00016480310016893