Levothyroxine use and the risk of colorectal cancer: a large population-based case–control study

Autor: Josephina G Kuiper, Aline C Fenneman, Anne H van der Spek, Elena Rampanelli, Max Nieuwdorp, Myrthe P P van Herk-Sukel, Valery E P P Lemmens, Ernst J Kuipers, Ron M C Herings, Eric Fliers

Publikováno v: Endocrine Connections, Vol 11, Iss 1, Pp 1-8 (2022)

Objective: Whether an association between oral levothyroxine use, leading to supraphysiological exposure of the colon to thyroid hormones, and risk of colorectal cancer exists in humans is unclear. We therefore aimed to assess whether the use of levo

Externí odkaz: https://doaj.org/article/363df29d828341cdacdb16618210ba10

HOXA13 in etiology and oncogenic potential of Barrett’s esophagus

Autor: Vincent T. Janmaat, Kateryna Nesteruk, Manon C. W. Spaander, Auke P. Verhaar, Bingting Yu, Rodrigo A. Silva, Wayne A. Phillips, Marcin Magierowski, Anouk van de Winkel, H. Scott Stadler, Tatiana Sandoval-Guzmán, Luc J. W. van der Laan, Ernst J. Kuipers, Ron Smits, Marco J. Bruno, Gwenny M. Fuhler, Nicholas J. Clemons, Maikel P. Peppelenbosch

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)

Barrett’s esophagus is a pro-oncogenic lesion in the proximal gastrointestinal tract, but with a distal colon-like morphology. Here the authors report that the distal HOX gene HOXA13 is expressed in Barrett’s esophagus and in single cells of the

Externí odkaz: https://doaj.org/article/469f4cbf24264d01b938927512f6b9a2

Socioeconomic differences in participation and diagnostic yield within the Dutch national colorectal cancer screening programme with faecal immunochemical testing

Autor: Miriam P. van der Meulen, Esther Toes-Zoutendijk, Manon C. W. Spaander, Evelien Dekker, Johannes M. G. Bonfrer, Anneke J. van Vuuren, Ernst J. Kuipers, Folkert J. van Kemenade, M. F. van Velthuysen, Maarten G. J. Thomeer, Harriët van Veldhuizen, Harry J. de Koning, Iris Lansdorp-Vogelaar, Monique E. van Leerdam

Publikováno v: PLoS ONE, Vol 17, Iss 2 (2022)

Background CRC mortality rates are higher for individuals with a lower socioeconomic status (SES). Screening could influence health inequalities. We therefore aimed to investigate SES differences in participation and diagnostic yield of FIT screening

Externí odkaz: https://doaj.org/article/dfd29eb8def1497cac14aa1cd1329a3e

Artificial Intelligence in Colon Capsule Endoscopy—A Systematic Review

Autor: Sarah Moen, Fanny E. R. Vuik, Ernst J. Kuipers, Manon C. W. Spaander

Publikováno v: Diagnostics, Vol 12, Iss 8, p 1994 (2022)

Background and aims: The applicability of colon capsule endoscopy in daily practice is limited by the accompanying labor-intensive reviewing time and the risk of inter-observer variability. Automated reviewing of colon capsule endoscopy images using

Externí odkaz: https://doaj.org/article/632baa76e34243cc82ac588cb41410dc

Adenoma Detection Rate and Risk for Interval Postcolonoscopy Colorectal Cancer in Fecal Immunochemical Test–Based Screening

Autor: Pieter H.A. Wisse, Nicole S. Erler, Sybrand Y. de Boer, Bert den Hartog, Marco Oudkerk Pool, Jochim S. Terhaar sive Droste, Claudia Verveer, Gerrit A. Meijer, Iris Lansdorp-Vogelaar, Ernst J. Kuipers, Evelien Dekker, Manon C.W. Spaander

Publikováno v: Annals of Internal Medicine, 175(10), 1366-1373. American College of Physicians
Annals of internal medicine, 175(10), 1366-1373. American College of Physicians

Background: The adenoma detection rate (ADR) is an essential quality indicator for endoscopists performing colonoscopies for colorectal cancer (CRC) screening as it is associated with postcolonoscopy CRCs (PCCRCs). Currently, data on ADRs of endoscop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d91ce36611ea4df4bf34a6f153a80403
https://doi.org/10.7326/m22-0301