Realist Approach to Social Policies (RASP) study to reduce socioeconomic health inequalities through systems change: protocol for a research project combining mixed-methods realist research with institutional action research

Autor: Susanne Tonnon, Jantien van Berkel, Emely de Vet, Ernst-Jan de Bruijn, Maikel Waardenburg, Yvonne la Grouw, Eline van Bennekom, Hilje van der Horst, Milou Haggenburg- Mohammed, Annemien Haveman-Nies, Tamara Madern, Marike Knoef

Publikováno v: BMJ Open, Vol 14, Iss 6 (2024)

Introduction Health inequalities are rooted in inequality in vital resources for health, including financial resources, a supportive informal network, a stable living situation, work or daytime activities or education and literacy. About 25% of Dutch

Externí odkaz: https://doaj.org/article/6a202f00f2a14d55a82ad0bb557b7d73

The financial and administrative burden of financially vulnerable households

Autor: Ernst-Jan De Bruijn

A substantial part of households in developed countries is financially vulnerable. These households face financial problems or are financially at risk for shocks in income or expenditures. Financially vulnerable households face financial burdens as m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::956e26939eb528487e33cc917cb8cb09
https://research.wur.nl/en/publications/the-financial-and-administrative-burden-of-financially-vulnerable

Multicenter phase II clinical trial of isolated lung perfusion in patients with lung metastases

Autor: Jan F. Gielis, Bart P. van Putte, Ernst A. de Bruijn, Laurens Denissen, Gunther Guetens, Thomas J van Brakel, Paul Van Schil, Alexander P.W.M. Maat, Jeroen M.H. Hendriks, Willem den Hengst, Inez Rodrigus, Paul Beckers, Michel I.M. Versteegh, Jerry Braun, Gert De Boeck, Wim Vergauwen, Patrick Lauwers, Filip Lardon

Publikováno v: The annals of thoracic surgery
Annals of thoracic surgery, 108(1), 167-174. Elsevier USA
Annals of Thoracic Surgery, 108(1), 167-174. Elsevier USA
Beckers, P A J, Versteegh, M I M, Van Brakel, T J, Braun, J, Van Putte, B, Maat, A P W M, Vergauwen, W, Rodrigus, I, Den Hengst, W, Lardon, F, De Bruijn, E, Guetens, G, De Boeck, G, Gielis, J F, Lauwers, P, Denissen, L, Hendriks, J M H & Van Schil, P E 2019, ' Multicenter Phase II Clinical Trial of Isolated Lung Perfusion in Patients With Lung Metastases ', Annals of Thoracic Surgery, vol. 108, no. 1, pp. 167-174 . https://doi.org/10.1016/j.athoracsur.2019.02.071
Annals of Thoracic Surgery, 108(1), 167-174. Elsevier Inc.
Annals of Thoracic Surgery, 108(1), 167-174. ELSEVIER SCIENCE INC

Background. Up to 66% of patients show local pulmonary disease progression after pulmonary metastasectomy. Regional treatment with isolated lung perfusion (ILuP) may improve local control with minimal systemic adverse effects. The aims of this study

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::795a21c24cc4593ba03d2222838db585
https://hdl.handle.net/10067/1612810151162165141

The V3/V5 integrin inhibitor cilengitide augments tumor response to melphalan isolated limb perfusion in a sarcoma model

Autor: Simon L. Goodman, Ann L.B. Seynhaeve, Sandra T. van Tiel, Curzio Rüegg, Timo L.M. ten Hagen, Gisela aan de Wiel-Ambagtsheer, Matthias Grell, Michael Meyring, Ernst A. de Bruijn, Alexander M.M. Eggermont

Publikováno v: International Journal of Cancer, 132(11), 2694-2704. Wiley-Liss Inc.

Isolated limb perfusion (ILP) with melphalan and tumor necrosis factor (TNF)-α is used to treat bulky, locally advanced melanoma and sarcoma. However, TNF toxicity suggests a need for better-tolerated drugs. Cilengitide (EMD 121974), a novel cyclic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30544a2ec63403cca0268c7930f49501
https://doi.org/10.1002/ijc.27940

Docetaxel and gemcitabine combination therapy in advanced transitional cell carcinoma of the urothelium: results of a phase II and pharmacologic study

Autor: Ernst A. de Bruijn, Gunter Guetens, Allan T. van Oosterom, Marc Martens, Robert A. A. Maes, J. Selleslach, Rita Aerts, Herlinde Dumez, Gert De Boeck

Publikováno v: Anti-Cancer Drugs. 18:211-218

Our objective was to determine the response to gemcitabine plus docetaxel in advanced urothelial transitional cell carcinoma in a phase II trial, and gemcitabine distribution between plasma and erythrocytes, following docetaxel administration. Patien

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e552895900c9fd03c72a6a7849d92696
https://doi.org/10.1097/cad.0b013e328010ee5c