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Non-parametric estimation of reciprocity and triadic effects in relational event networks

Publikováno v: Social Networks. 68:296-305

Relational event networks arise naturally from social interactions: interactions can be considered time-stamped edges between vertices of social actors. By studying the factors that influence the interaction inter-arrival times we can get insight in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::81dee425504a833e230f73fc8fd114f6
https://doi.org/10.1016/j.socnet.2021.08.004

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Introducing a general class of species diversification models for phylogenetic trees

Autor: Rampal S. Etienne, Bart Haegeman, Francisco Richter, Ernst Wit

Publikováno v: Statistica Neerlandica
Statistica Neerlandica, 2020, 74 (3), pp.261-274. ⟨10.1111/stan.12205⟩
Statistica Neerlandica, Wiley, 2020, 74 (3), pp.261-274. ⟨10.1111/stan.12205⟩
Statistica Neerlandica, 74(3), 261-274. Wiley

International audience; Phylogenetic trees are types of networks that describe the temporal relationship between individuals, species, or other units that are subject to evolutionary diversification. Many phylogenetic trees are constructed from molec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1152d36ce185902ae6cdbd97ce40508
https://research.rug.nl/en/publications/3074bf20-b48e-417d-ade6-789999ba3216

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Sparse relative risk regression models

Autor: Hassan Pazira, Ernst Wit, Fentaw Abegaz, Javier González, Luigi Augugliaro

Publikováno v: Biostatistics, 21(2)
Biostatistics

Summary Clinical studies where patients are routinely screened for many genomic features are becoming more routine. In principle, this holds the promise of being able to find genomic signatures for a particular disease. In particular, cancer survival

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8175af8e25e0ed3569f7d821f47a6c8
https://hdl.handle.net/11370/1175bca5-a60f-4e63-b256-58210fb10e5d

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Was R < 1 before the English lockdowns?:On modelling mechanistic detail, causality and inference about Covid-19

Autor: Simon N. Wood, Ernst Wit

Publikováno v: Wood, S N & Wit, E C 2021, ' Was R < 1 before the English lockdowns? On modelling mechanistic detail, causality and inference about Covid-19 ', PLoS ONE, vol. 16, no. 9, e0257455 . https://doi.org/10.1371/journal.pone.0257455
PLoS ONE, Vol 16, Iss 9, p e0257455 (2021)
PLoS ONE

Detail is a double edged sword in epidemiological modelling. The inclusion of mechanistic detail in models of highly complex systems has the potential to increase realism, but it also increases the number of modelling assumptions, which become harder

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ba2f2fe25036f42053e9d194d1f0fcb
https://www.pure.ed.ac.uk/ws/files/235654410/journal.pone.0257455_1_.pdf

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Bistability in fatty-acid oxidation resulting from substrate inhibition

Autor: Fentaw Abegaz, Dirk-Jan Reijngoud, Anne-Claire M F Martines, Ernst Wit, Marcel A. Vieira-Lara, Melany Rios-Morales, Barbara M. Bakker

Publikováno v: PLoS Computational Biology, 17(8):e1009259. PUBLIC LIBRARY SCIENCE
PLoS Computational Biology, Vol 17, Iss 8, p e1009259 (2021)
Abegaz, F, Martines, A C M F, Vieira Lara, M A, Morales, M R, Reijngoud, D J, Wit, E C & Bakker, B M 2021, ' Bistability in fatty-acid oxidation resulting from substrate inhibition ', PLoS Computational Biology, vol. 17, no. 8, e1009259 . https://doi.org/10.1371/journal.pcbi.1009259
PLoS Computational Biology, 17(8):e1009259. Public Library of Science
PLoS Computational Biology

In this study we demonstrated through analytic considerations and numerical studies that the mitochondrial fatty-acid β-oxidation can exhibit bistable-hysteresis behavior. In an experimentally validated computational model we identified a specific r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54804c6df538b339104ea4042c590e89
https://research.rug.nl/en/publications/e0245b56-26f1-4a46-9f9f-2c071fafac60

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Selecting the tuning parameter in penalized Gaussian graphical models

Autor: Angelo Mineo, Ernst Wit, Ivan Vujacic, Antonino Abbruzzo

Publikováno v: Statistics and Computing, 29(3), 559-569. SPRINGER

Penalized inference of Gaussian graphical models is a way to assess the conditional independence structure in multivariate problems. In this setting, the conditional independence structure, corresponding to a graph, is related to the choice of the tu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b08111854c89e2b30676730b9a6716e9
https://research.rug.nl/en/publications/16692e21-4e05-418c-8e54-1942f8130c9e

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Variance Components Models for Analysis of Big Family Data of Health Outcomes in the Lifelines Cohort Study

Autor: Edwin R. van den Heuvel, Nynke Smidt, Harold Snieder, Ernst Wit, Nino Demetrashvili

Publikováno v: Twin research and human genetics, 22(1), 4-13. Cambridge University Press
Twin Research and Human Genetics, 22(1), 4-13. Cambridge University Press

Large multigenerational cohort studies offer powerful ways to study the hereditary effects on various health outcomes. However, accounting for complex kinship relations in big data structures can be methodologically challenging. The traditional kinsh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8314a6740b6d8054e4bde4b95116da4
https://hdl.handle.net/11370/ffe1c8a6-8b40-47c3-8a35-976a99d49feb

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