Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Ernst Suidgeest"'
Autor:
Narek Manukjan, Daria Majcher, Peter Leenders, Florian Caiment, Marcel van Herwijnen, Hubert J. Smeets, Ernst Suidgeest, Louise van der Weerd, Tim Vanmierlo, Jacobus F. A. Jansen, Walter H. Backes, Robert J. van Oostenbrugge, Julie Staals, Daniel Fulton, Zubair Ahmed, W. Matthijs Blankesteijn, Sébastien Foulquier
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-17 (2023)
Abstract Cerebral small vessel disease is characterised by decreased cerebral blood flow and blood–brain barrier impairments which play a key role in the development of white matter lesions. We hypothesised that cerebral hypoperfusion causes local
Externí odkaz:
https://doaj.org/article/a3555923891f4aa483f56460bea38e71
Autor:
Elsa C. Kuijper, Maurice Overzier, Ernst Suidgeest, Oleh Dzyubachyk, Cécile Maguin, Jean-Baptiste Pérot, Julien Flament, Yavuz Ariyurek, Hailiang Mei, Ronald A.M. Buijsen, Louise van der Weerd, Willeke van Roon-Mom
Publikováno v:
Neurobiology of Disease, Vol 190, Iss , Pp 106368- (2024)
In Huntington disease, cellular toxicity is particularly caused by toxic protein fragments generated from the mutant huntingtin (HTT) protein. By modifying the HTT protein, we aim to reduce proteolytic cleavage and ameliorate the consequences of muta
Externí odkaz:
https://doaj.org/article/0b4874be3df4497fb539494749184266
Autor:
Zhenfeng Yu, Yuanyuan He, Timo Schomann, Kefan Wu, Yang Hao, Ernst Suidgeest, Hong Zhang, Christina Eich, Luis J. Cruz
Publikováno v:
Pharmaceutics, Vol 16, Iss 1, p 91 (2024)
There was an error in the original publication [...]
Externí odkaz:
https://doaj.org/article/05ebfb00f36b4e4ab8ca2d7f20ae0ff5
Autor:
Zhenfeng Yu, Yuanyuan He, Timo Schomann, Kefan Wu, Yang Hao, Ernst Suidgeest, Hong Zhang, Christina Eich, Luis J. Cruz
Publikováno v:
Pharmaceutics, Vol 15, Iss 12, p 2755 (2023)
In the original publication [...]
Externí odkaz:
https://doaj.org/article/5593d8bb0fe54fa2844e448b5502cabd
Autor:
Zhenfeng Yu, Yuanyuan He, Timo Schomann, Kefan Wu, Yang Hao, Ernst Suidgeest, Hong Zhang, Christina Eich, Luis J. Cruz
Publikováno v:
Pharmaceutics, Vol 14, Iss 12, p 2796 (2022)
Here, we describe the synthesis of a novel type of rare-earth-doped nanoparticles (NPs) for multimodal imaging, by combining the rare-earth elements Ce, Gd and Nd in a crystalline host lattice consisting of CaF2 (CaF2: Ce, Gd, Nd). CaF2: Ce, Gd, Nd N
Externí odkaz:
https://doaj.org/article/6dc5f439edf8412e99d884889d223083
Autor:
Jorge Miguel Amaya, Ernst Suidgeest, Isabelle Sahut-Barnola, Typhanie Dumontet, Nathanaëlle Montanier, Guilhem Pagès, Cécile Keller, Louise van der Weerd, Alberto M. Pereira, Antoine Martinez, Onno C. Meijer
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Chronic exposure to high circulating levels of glucocorticoids has detrimental effects on health, including metabolic abnormalities, as exemplified in Cushing’s syndrome (CS). Magnetic resonance imaging (MRI) studies have found volumetric changes i
Externí odkaz:
https://doaj.org/article/e596fd4c771e4e17bbc71da6814d87aa
Autor:
Leon P Munting, Marc Derieppe, Ernst Suidgeest, Lydiane Hirschler, Matthias JP van Osch, Baudouin Denis de Senneville, Louise van der Weerd
Publikováno v:
eLife, Vol 10 (2021)
Impaired cerebrovascular function is an early biomarker for cerebral amyloid angiopathy (CAA), a neurovascular disease characterized by amyloid-β accumulation in the cerebral vasculature, leading to stroke and dementia. The transgenic Swedish Dutch
Externí odkaz:
https://doaj.org/article/4bb59bd105b94d219471f6eca67f1dad
Autor:
Zhenfeng Yu, Yuanyuan He, Timo Schomann, Kefan Wu, Yang Hao, Ernst Suidgeest, Hong Zhang, Christina Eich, Luis J. Cruz
Publikováno v:
Pharmaceutics, Vol 14, Iss 4, p 840 (2022)
Nowadays, cancer poses a significant hazard to humans. Limitations in early diagnosis techniques not only result in a waste of healthcare resources but can even lead to delays in diagnosis and treatment, consequently reducing cure rates. Therefore, i
Externí odkaz:
https://doaj.org/article/ad6d6ee7c566462b86a8475bce8fe09a
Autor:
Marjolein Bulk, Ingrid Hegeman-Kleinn, Boyd Kenkhuis, Ernst Suidgeest, Willeke van Roon-Mom, Jan Lewerenz, Sjoerd van Duinen, Itamar Ronen, Louise van der Weerd
Publikováno v:
NeuroImage: Clinical, Vol 28, Iss , Pp 102498- (2020)
Previous MRI studies consistently reported iron accumulation within the striatum of patients with Huntington’s disease (HD). However, the pattern and origin of iron accumulation is poorly understood. This study aimed to characterize the histopathol
Externí odkaz:
https://doaj.org/article/16f59392ae9d4403a65794b77d7eafb2
Autor:
Lucia A. A. Giannini, Marjolein Bulk, Boyd Kenkhuis, Ana Rajicic, Shamiram Melhem, Ingrid Hegeman‐Kleinn, Lucia Bossoni, Ernst Suidgeest, Elise G. P. Dopper, John C. van Swieten, Louise van der Weerd, Harro Seelaar
Publikováno v:
Brain Pathology. Wiley-Blackwell
Neuroinflammation has been implicated in frontotemporal lobar degeneration (FTLD) pathophysiology, including in genetic forms with microtubule-associated protein tau (MAPT) mutations (FTLD-MAPT) or chromosome 9 open reading frame 72 (C9orf72) repeat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1019fa9a095705c9a85660782def34f
https://pure.eur.nl/en/publications/d9caff50-257b-414e-b958-6d46cecb481a
https://pure.eur.nl/en/publications/d9caff50-257b-414e-b958-6d46cecb481a