Zobrazeno 1 - 10
of 535
pro vyhledávání: '"Ernst, Holler"'
Autor:
Jochen T. Frueh, Julia Campe, Daniele Yumi Sunaga-Franze, Nikita A. Verheyden, Sakhila Ghimire, Elisabeth Meedt, Denise Haslinger, Sabine Harenkamp, Daniel Staudenraus, Sascha Sauer, Andreas Kreft, Ralf Schubert, Michael Lohoff, Andreas Krueger, Halvard Bonig, Andreas G. Chiocchetti, Robert Zeiser, Ernst Holler, Evelyn Ullrich
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
Interferon regulatory factor 4 (IRF4) is a master transcription factor that regulates T helper cell (Th) differentiation. It interacts with the Basic leucine zipper transcription factor, ATF-like (BATF), depletion of which in CD4+ T cells abrogates a
Externí odkaz:
https://doaj.org/article/0e061017555b4bc0b1aa91d36567a9dd
Autor:
Laura Schreiber, Sakhila Ghimire, Andreas Hiergeist, Kathrin Renner, Michael Althammer, Nathalie Babl, Alice Peuker, Gabriele Schoenhammer, Katrin Hippe, Andre Gessner, Christin Albrecht, Fransziska Pielmeier, Maike Büttner-Herold, Heiko Bruns, Petra Hoffmann, Wolfgang Herr, Ernst Holler, Katrin Peter, Marina Kreutz, Carina Matos
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Vitamin D3 regulates a variety of biological processes irrespective of its well-known importance for calcium metabolism. Epidemiological and animal studies indicate a role in immune regulation, intestinal barrier function and microbiome diversity. He
Externí odkaz:
https://doaj.org/article/1e562ae9c62540c28a3dd995c00c2c58
Autor:
Albert Rosenberger, Rachel E. Crossland, Ralf Dressel, Dieter Kube, Daniel Wolff, Gerald Wulf, Heike Bickeböller, Anne Dickinson, Ernst Holler
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionData on genomic susceptibility for adverse outcomes after hematopoietic stem cell transplantation (HSCT) for recipients are scarce.MethodsWe performed a genome wide association study (GWAS) to identify genes associated with survival/morta
Externí odkaz:
https://doaj.org/article/28fe5289e59f467c9ac274bb9c1be77a
Publikováno v:
Radiation Oncology, Vol 17, Iss 1, Pp 1-12 (2022)
Abstract Background Total body irradiation (TBI)-based-conditioning before allogeneic hematopoietic stem cell transplantation (allo-HSCT) is standard of care in patients with acute myeloid leukemia (AML) but can cause long-term morbidity. Data on the
Externí odkaz:
https://doaj.org/article/09d3b435c4fa42ee91a2b5f37538b1ec
Autor:
Florent Malard, Michael Loschi, Anne Huynh, Thomas Cluzeau, Sarah Guenounou, Faezeh Legrand, Leonardo Magro, Corentin Orvain, Amandine Charbonnier, Marta Panz-Klapuch, Deborah Desmier, Jean-Baptiste Mear, Jérôme Cornillon, Christine Robin, Etienne Daguindau, Karin Bilger, Maria J.G.T. Vehreschild, Patrice Chevallier, Hélène Labussière-Wallet, Clémence Mediavilla, Marie-Anne Couturier, Claude-Eric Bulabois, Vincent Camus, Sylvain Chantepie, Patrice Ceballos, Béatrice Gaugler, Ernst Holler, Joël Doré, Emmanuel Prestat, Cyrielle Gasc, Emilie Plantamura, Mohamad Mohty
Publikováno v:
EClinicalMedicine, Vol 62, Iss , Pp 102111- (2023)
Summary: Background: Failure of gastrointestinal acute graft-versus-host disease (GI-aGvHD) to respond to steroid therapy is associated with limited further therapeutic options. We aimed to assess the safety and efficacy of the first-in-human use of
Externí odkaz:
https://doaj.org/article/358931ad3a1e470aadcd16ab7663faaf
Autor:
Lucia Scheidler, Katrin Hippe, Sakhila Ghimire, Daniela Weber, Markus Weber, Elisabeth Meedt, Petra Hoffmann, Petra Lehn, Ralph Burkhardt, Andreas Mamilos, Matthias Edinger, Daniel Wolff, Hendrik Poeck, Matthias Evert, Andre Gessner, Wolfgang Herr, Ernst Holler
Publikováno v:
Haematologica, Vol 108, Iss 11 (2023)
Intestinal immunoglobulin A (IgA) is strongly involved in microbiota homeostasis. Since microbiota disruption is a major risk factor of acute graft-versus-host disease (GvHD), we addressed the kinetics of intestinal IgA-positive (IgA+) plasma cells b
Externí odkaz:
https://doaj.org/article/8f1272643dd64c11be40b69110048012
Autor:
Carina Matos, Andreas Mamilos, Pranali N. Shah, Elisabeth Meedt, Daniela Weber, Saroj Ghimire, Andreas Hiergeist, André Gessner, Anne Dickinson, Ralf Dressel, Lutz Walter, Klaus Stark, Iris M. Heid, Hendrik Poeck, Matthias Edinger, Daniel Wolff, Wolfgang Herr, Ernst Holler, Marina Kreutz, Sakhila Ghimire
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The vitamin D receptor (VDR) is critical in regulating intestinal homeostasis and emerging evidence demonstrates that VDR deficiency is a critical factor in inflammatory bowel disease pathology. However, no clinical data exist regarding the intestina
Externí odkaz:
https://doaj.org/article/9571dadbd1b24596a6a8f43daff39e2f
Publikováno v:
BMC Health Services Research, Vol 21, Iss 1, Pp 1-12 (2021)
Abstract Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is the only potentially curative treatment option for many patients with hematological disorders but it includes a significant risk of mortality and long-term morbidity
Externí odkaz:
https://doaj.org/article/2ba24d668a154467b88753537005ebae
Autor:
Sakhila Ghimire, Katharina U. Ederer, Elisabeth Meedt, Daniela Weber, Carina Matos, Andreas Hiergeist, Florian Zeman, Daniel Wolff, Matthias Edinger, Hendrik Poeck, Wolfgang Herr, André Gessner, Ernst Holler, Sigrid Bülow
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The role of IL-22 in adult patients undergoing allogeneic stem cell transplantation (SCT) is of major interest since animal studies showed a protective and regenerative effect of IL-22 in graft versus host disease (GvHD). However, no clinical data ex
Externí odkaz:
https://doaj.org/article/5bef20ac96274cb6b2abc1817d4572d3
Autor:
Carina Matos, Katrin Peter, Laura Weich, Alice Peuker, Gabriele Schoenhammer, Tobias Roider, Sakhila Ghimire, Nathalie Babl, Sonja Decking, Martina Güllstorf, Nicolaus Kröger, Kathrin Hammon, Wolfgang Herr, Klaus Stark, Iris M. Heid, Kathrin Renner, Ernst Holler, Marina Kreutz
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Application of anti-thymocyte globulin (ATG) is a widely used strategy for the prevention of graft-versus-host disease (GvHD). As vitamin D3 serum levels are also discussed to affect hematopoietic stem cell transplantation (HSCT) outcome and GvHD dev
Externí odkaz:
https://doaj.org/article/64036cbf5a4049d78425362fdbfc887d