Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ernie Au"'
Publikováno v:
The FASEB Journal. 33
Microtubules and actin filaments are dynamic cytoskeletal structures that interact with motor proteins and play a fundamental role in many essential biological processes including cell division, ce...
Autor:
Joseph E. Rupert, Ashok Narasimhan, Yunlong Liu, Daenique H A Jengelley, Xiaoyu Lu, Sha Cao, Leonidas G. Koniaris, Ernie Au, Libbie M. Silverman, Jianguo Liu, Teresa A. Zimmers, Thomas M. O’Connell, George E. Sandusky, Yanlin Jiang, Andrea Bonetto
Publikováno v:
The Journal of Experimental Medicine
Cachexia increases morbidity and mortality. Rupert et al. show PDAC cachexia results from tissue crosstalk via an IL-6 trans-signaling loop. Malignant cells signal via IL-6 to muscle and fat, muscle to fat via sIL6R, and fat to muscle via lipids and
Autor:
Ernie Au
Publikováno v:
Biophysical Journal. 118:620a
Publikováno v:
Biophysical Journal. 116:276a-277a
Publikováno v:
Biophysical Journal. 116:278a
Autor:
Nicholas J. Zyromski, Marc D. Kohli, Guanglong Jiang, Atilla Nakeeb, Teresa A. Zimmers, Milan Radovich, Stephen F. Konieczny, Michael G. House, Eugene P. Ceppa, Andrea Bonetto, Daniel E. I. Schloss, Leonidas G. Koniaris, Xiaoling Zhong, Patrick G. Schweickert, Yanlin Jiang, Katharyn Hannaford, Cynthia Brooks, Bert H. O'Neil, Yunlong Lui, C. Max Schmidt, Marianne Pons, Ernie Au, Jianguo Liu, Safi Shahda, Christophe Poirier, Joshua Kayes, BA Hancock
Publikováno v:
Cancer Research. 76:B35-B35
Background: Patients with pancreatic ductal adenocarcinoma (PDAC) suffer the highest rates of cachexia, with ~85% experiencing muscle and fat loss. Weight loss and muscle loss correlate with mortality in PDAC. Patients with cachexia experience fatigu