Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ernesto Relova-Hernández"'
Autor:
Beatriz Pérez-Massón, Yazmina Quintana-Pérez, Yaima Tundidor, Dayana Pérez-Martínez, Camila Castro-Martínez, Mario Pupo-Meriño, Ivette Orosa, Ernesto Relova-Hernández, Rosmery Villegas, Osmany Guirola, Gertrudis Rojas
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract SARS-CoV-2 receptor binding domain (RBD) mediates viral entry into human cells through its interaction with angiotensin converting enzyme 2 (ACE2). Most neutralizing antibodies elicited by infection or vaccination target this domain. Such a
Externí odkaz:
https://doaj.org/article/5fb8da803ded4e869e1bc185a4ff61c6
Autor:
Gertrudis Rojas, Ernesto Relova-Hernández, Annia Pérez-Riverón, Camila Castro-Martínez, Osmany Diaz-Bravo, Yanelys Cabrera Infante, Tania Gómez, Joaquín Solozábal, Ana Beatriz DíazBravo, Maren Schubert, Marlies Becker, Beatriz Pérez-Massón, Dayana Pérez-Martínez, Rydell Alvarez-Arzola, Osmany Guirola, Glay Chinea, Luis Graca, Stefan Dübel, Kalet León, Tania Carmenate
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-20 (2023)
Abstract Interleukin-2 (IL-2) engineered versions, with biased immunological functions, have emerged from yeast display and rational design. Here we reshaped the human IL-2 interface with the IL-2 receptor beta chain through the screening of phage-di
Externí odkaz:
https://doaj.org/article/fc54223928184a9ab56c2dddb4e1f03a
Autor:
Enrique Noa, Ubel Ramirez, Tammy Boggiano, Luis Javier González, Gretchen Bergado, Vicente Verez-Bencomo, Laura Rodriguez, Yury Valdés-Balbín, Raine Garrido, Luis Ariel Espinosa, Yanet Climent, Rocmira Perez, Eduardo Ojito, Kalet León Monzón, Jean-Pierre Soubal, Sonsire Fernández, Daniel G. Rivera, Darielys Santana-Mederos, Felix Cardoso, Claudia Acosta, Lauren Quintero, Yanelys Cabrera Infante, Fabrizio Chiodo, Anamary Suarez, Sum Lai Losada, Tays Hernández, Reinaldo Oliva, Franciscary Pi, Manuel G. Ricardo, Belinda Sánchez Ramírez, Dagmar García-Rivera, Annet Valdes, Mario Landys, Cheng Fang, Yanira Méndez, Juliet Enriquez, Yassel Ramos, Humberto Gonzalez, Guang-Wu Chen, Ernesto Relova-Hernández, Tania Carmenate, Françoise Paquet, Gertrudis Rojas, Mildrey Farinas
Publikováno v:
ACS Chemical Biology
ACS Chemical Biology, American Chemical Society, 2021, 16 (7), pp.1223-1233. ⟨10.1021/acschembio.1c00272⟩
ACS Chemical Biology, American Chemical Society, 2021, 16 (7), pp.1223-1233. ⟨10.1021/acschembio.1c00272⟩
Controlling the global COVID-19 pandemic depends, among other measures, on developing preventive vaccines at an unprecedented pace. Vaccines approved for use and those in development intend to use neutralizing antibodies to block viral sites binding
Autor:
Stephan von Gunten, Hans-Uwe Simon, Mayrel Labrada, Ernesto Relova-Hernández, Denise Dorvignit, Circe Mesa, Kayluz Frias Boligan, Marilyn Clavell, Armando López, Alejandro López-Requena
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Dorvignit, Denise; Frias Boligan, Kayluz; Relova-Hernández, Ernesto; Clavell, Marilyn; López, Armando; Labrada, Mayrel; Simon, Hans-Uwe; López-Requena, Alejandro; Mesa, Circe; von Gunten, Stephan (2019). Antitumor effects of the GM3(Neu5Gc) ganglioside-specific humanized antibody 14F7hT against Cmah-transfected cancer cells. Scientific Reports, 9(1), p. 9921. Nature Publishing Group 10.1038/s41598-019-46148-1
Scientific Reports
Dorvignit, Denise; Frias Boligan, Kayluz; Relova-Hernández, Ernesto; Clavell, Marilyn; López, Armando; Labrada, Mayrel; Simon, Hans-Uwe; López-Requena, Alejandro; Mesa, Circe; von Gunten, Stephan (2019). Antitumor effects of the GM3(Neu5Gc) ganglioside-specific humanized antibody 14F7hT against Cmah-transfected cancer cells. Scientific Reports, 9(1), p. 9921. Nature Publishing Group 10.1038/s41598-019-46148-1
The GM3(Neu5Gc) ganglioside represents a tumor-specific antigen that is considered a promising target for cancer immunotherapy. We previously demonstrated that the humanized antibody 14F7hT, specific for this ganglioside, exhibited significant antitu
Autor:
Tammy Boggiano-Ayo, Julio Palacios-Oliva, Sumlai Lozada-Chang, Ernesto Relova-Hernandez, Jose Gomez-Perez, Gonzalo Oliva, Lourdes Hernandez, Alexi Bueno-Soler, Daidee Montes de Oca, Osvaldo Mora, Roberto Machado-Santisteban, Dayana Perez-Martinez, Beatriz Perez-Masson, Yanelys Cabrera Infante, Lisandra Calzadilla-Rosado, Yaima Ramirez, Judey Aymed-Garcia, Ingrid Ruiz-Ramirez, Yamile Romero, Tania Gomez, Luis A. Espinosa, Luis Javier Gonzalez, Annia Cabrales, Osmany Guirola, Kathya Rashida de la Luz, Franciscary Pi-Estopiñan, Belinda Sanchez-Ramirez, Dagmar Garcia-Rivera, Yuri Valdes-Balbin, Gertrudis Rojas, Kalet Leon-Monzon, Eduardo Ojito-Magaz, Eugenio Hardy
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
We have developed a single process for producing two key COVID-19 vaccine antigens: SARS-CoV-2 receptor binding domain (RBD) monomer and dimer. These antigens are featured in various COVID-19 vaccine formats, including SOBERANA 01 and the licensed SO
Externí odkaz:
https://doaj.org/article/e0706f0426fc462d821685ef6ce26f54