Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Ernesto Raul Caffarena"'
Autor:
Marcos Gustavo Araujo Schwarz, Deborah Antunes, Paloma Rezende Corrêa, Antônio José da Silva-Gonçalves, Wladimir Malaga, Ernesto Raul Caffarena, Christophe Guilhot, Leila Mendonça-Lima
Publikováno v:
Frontiers in Microbiology, Vol 11 (2021)
Tuberculosis is a world widespread disease, caused by Mycobacterium tuberculosis (M.tb). Although considered an obligate aerobe, this organism can resist life-limiting conditions such as microaerophily mainly due to its set of enzymes responsible for
Externí odkaz:
https://doaj.org/article/626174fdadcc4b0baede5747c8d1d166
Autor:
Clara Carolina Silva De Oliveira, Gabriel Rodrigues Coutinho Pereira, Jamile Yvis Santos De Alcantara, Deborah Antunes, Ernesto Raul Caffarena, Joelma Freire De Mesquita
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0215508 (2019)
Brain-derived neurotrophic factor (BDNF) plays an important role in neurogenesis and synapse formation. The V66M is the most prevalent BDNF mutation in humans and impairs the function and distribution of BDNF. This mutation is related to several psyc
Externí odkaz:
https://doaj.org/article/e829dd976d5e4c8a8ea2fe633483856c
Autor:
Allan Peres-da-Silva, Deborah Antunes, André Luiz Quintanilha Torres, Ernesto Raul Caffarena, Elisabeth Lampe
Publikováno v:
Viruses, Vol 11, Iss 8, p 691 (2019)
Hepatitis C virus genotype 1a (HCV-1a) comprises clades I and II. The Q80K polymorphism is found predominantly in clade I but rarely in clade II. Here, we investigated whether natural polymorphisms in HCV-1a clade II entailed structural protein chang
Externí odkaz:
https://doaj.org/article/b41002846f5342a28eedd1084719de7e
Autor:
Amanda Sutter, Deborah Antunes, Mariana Silva-Almeida, Maurício Garcia de Souza Costa, Ernesto Raul Caffarena
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 112, Iss 9, Pp 617-625
BACKGROUND Leishmanolysins have been described as important parasite virulence factors because of their roles in the infection of promastigotes and resistance to host’s defenses. Leishmania (Viannia) braziliensis contains several leishmanolysin gen
Externí odkaz:
https://doaj.org/article/270a4e50b2fe4267a687246dd1c4be17
Autor:
Fernando Augusto T. P. Meireles, Deborah Antunes, Jairo R. Temerozo, Dumith Chequer Bou-Habib, Ernesto Raul Caffarena
Publikováno v:
Journal of Biomolecular Structure and Dynamics. :1-17
The neuropeptide pituitary adenylate cyclase-activating polypeptide (PACAP) belongs to the glucagon/secretin family. PACAP interacts with the pituitary adenylate cyclase-activating polypeptide receptor type 1 (PAC1) and vasoactive intestinal peptide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::942ba88d0376bd0e685840c3a3d1f083
https://doi.org/10.1080/07391102.2023.2213349
https://doi.org/10.1080/07391102.2023.2213349
Autor:
Rafael Eduardo Oliveira Rocha, Diego César Batista Mariano, Tiago Silva Almeida, Leon Sulfierry CorrêaCosta, Pedro Henrique Camargo Fischer, Lucianna Helene Santos, Ernesto Raul Caffarena, Carlos Henrique da Silveira, Leonida M. Lamp, Monica Lisa Fernandez‐Quintero, Klaus Roman Liedl, Raquel Cardoso de Melo‐Minardi, Leonardo Henrique França de Lima
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 91:218-236
β-glucosidases play a pivotal role in second-generation biofuel (2G-biofuel) production. For this application, thermostable enzymes are essential due to the denaturing conditions on the bioreactors. Random amino acid substitutions have originated ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90d3dafa489316389707403565b073a4
https://doi.org/10.1002/prot.26424
https://doi.org/10.1002/prot.26424
Publikováno v:
Physical Chemistry Chemical Physics. 23:3993-4006
The activation of GABAA receptors by the neurotransmitter gamma-aminobutyric acid mediates the rapid inhibition response in the central nervous system of mammals. Many neurological and mental health disorders arise from alterations in the structure o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0b56a948c3fa7a618e43bc9b4891675
https://doi.org/10.1039/d0cp05081d
https://doi.org/10.1039/d0cp05081d
Autor:
Ernesto Raul Caffarena, Geraldo Rodrigues Sartori, Wilson Savino, Disraeli C. A. Vasconcelos, Beatriz Chaves, João Hermínio Martins da Silva, Vinicius Cotta-de-Almeida
Publikováno v:
ACS Omega, Vol 5, Iss 27, Pp 16379-16385 (2020)
ACS Omega
ACS Omega
Integrins are cell adhesion receptors that transmit bidirectional signals across the plasma membrane. They are noncovalently linked heterodimeric molecules consisting of two subunits and act as biomarkers in several pathologies. Thus, according to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce93b0c5e8c001fd866afefc6af2890f
https://doaj.org/article/c25018fd021645a2be72818376a0a48f
https://doaj.org/article/c25018fd021645a2be72818376a0a48f
Publikováno v:
RNA Biology. 17:1001-1008
Noncoding RNA (ncRNA) genes produce transcripts involved in a wide range of functions, including catalytic and regulatory functions. Besides, some transcripts have highly complex structures that ma...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee0915bb4b622be004f0d0b760a4e96e
https://doi.org/10.1080/15476286.2020.1748922
https://doi.org/10.1080/15476286.2020.1748922
Autor:
Lucianna Helene Santos, Gisele Vieira Rocha, Rafael Ferreira Soares, Ana Carolina Ramos Guimarães, Ernesto Raul Caffarena, Deborah Antunes, Leonardo Soares Bastos
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 38:2047-2056
The Trypanosoma cruzi ribose-5-phosphate isomerase B (TcRpiB) is a crucial piece in the pentose phosphate pathway and thus is a potential drug target for treatment of Chagas’ disease. TcRpiB residu...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f38da309176a1941850fe0ca923c835
https://doi.org/10.1080/07391102.2019.1626769
https://doi.org/10.1080/07391102.2019.1626769