Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Ernesto Martín-Nuñez"'
Autor:
Lara Matilla, Eva Jover, Mattie Garaikoetxea, Ernesto Martín-Nuñez, Vanessa Arrieta, Amaia García-Peña, Adela Navarro, Amaya Fernández-Celis, Alicia Gainza, Virginia Álvarez, Diego Álvarez de la Rosa, Rafael Sádaba, Frederic Jaisser, Natalia López-Andrés
Publikováno v:
Hypertension. 79:1724-1737
Background: There are sex differences in the pathophysiology of aortic valve (AV) calcification in patients with aortic stenosis, although the molecular and cellular mechanisms have not been elucidated. Aldosterone (Aldo) promotes proteoglycan synthe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a88242ec64abb01ce49f2f1ba799ded2
https://doi.org/10.1161/hypertensionaha.122.19526
https://doi.org/10.1161/hypertensionaha.122.19526
Autor:
Lara Matilla, Ernesto Martín-Núñez, Mattie Garaikoetxea, Adela Navarro, Ibai Tamayo, Amaya Fernández-Celis, Alicia Gainza, Joaquín Fernández-Irigoyen, Enrique Santamaría, Pieter Muntendam, Virginia Álvarez, Rafael Sádaba, Eva Jover, Natalia López-Andrés
Publikováno v:
Biology of Sex Differences, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Background Aortic stenosis (AS) is characterized by inflammation, fibrosis, osteogenesis and angiogenesis. Men and women develop these mechanisms differently. Galectin-3 (Gal-3) is a pro-inflammatory and pro-osteogenic lectin in AS. In this
Externí odkaz:
https://doaj.org/article/217c4fe6128f48c391c01c6594c7805f
Autor:
Ernesto Martín-Núñez, Miriam Goñi-Olóriz, Lara Matilla, Mattie Garaikoetxea, Laura Mourino-Alvarez, Adela Navarro, Amaya Fernández-Celis, Ibai Tamayo, Alicia Gainza, Virginia Álvarez, Rafael Sádaba, María G. Barderas, Eva Jover, Natalia López-Andrés
Publikováno v:
Cardiovascular Diabetology, Vol 22, Iss 1, Pp 1-15 (2023)
Abstract Background Diabetes mellitus (DM) accelerates the progression of aortic stenosis (AS), but how their underlying molecular mechanisms interact is not clear. Moreover, whether DM contributes to clinically relevant sex-differences in AS is unkn
Externí odkaz:
https://doaj.org/article/2cd3d7f1dab649a9ad0cd270d6ed8337
Autor:
Eva Jover, Lara Matilla, Ernesto Martín-Núñez, Mattie Garaikoetxea, Adela Navarro, Amaya Fernández-Celis, Alicia Gainza, Vanessa Arrieta, Amaia García-Peña, Virginia Álvarez, Rafael Sádaba, Frederic Jaisser, Natalia López-Andrés
Publikováno v:
Biology of Sex Differences, Vol 13, Iss 1, Pp 1-17 (2022)
Highlights NGAL is expressed by inflammatory infiltrates and active VICs in the stenotic AV, being predominantly associated to inflammation, osteogenesis, and calcification. The levels of NGAL are higher in VICs and AVs from men than women’s and ar
Externí odkaz:
https://doaj.org/article/cb11e3f659634180ab12dcbd338bdf98
Autor:
Tamara Sastre-Oliva, Nerea Corbacho-Alonso, Elena Rodriguez-Sanchez, Elisa Mercado-García, Ines Perales-Sanchez, German Hernandez-Fernandez, Cristina Juarez-Alia, Teresa Tejerina, Luis F. López-Almodóvar, Luis R. Padial, Pedro L. Sánchez, Ernesto Martín-Núñez, Natalia López-Andrés, Gema Ruiz-Hurtado, Laura Mourino-Alvarez, Maria G. Barderas
Publikováno v:
Antioxidants, Vol 13, Iss 1, p 108 (2024)
Calcific aortic valve disease (CAVD) and coronary artery disease (CAD) are related cardiovascular diseases in which common mechanisms lead to tissue calcification. Oxidative stress plays a key role in these diseases and there is also evidence that th
Externí odkaz:
https://doaj.org/article/6e7cdbee88f146f494f7064ff564f8f7
Autor:
Javier Donate-Correa, Ernesto Martín-Núñez, Alberto Martin-Olivera, Carmen Mora-Fernández, Víctor G. Tagua, Carla M. Ferri, Ángel López-Castillo, Alejandro Delgado-Molinos, Victoria Castro López-Tarruella, Miguel A. Arévalo-Gómez, Nayra Pérez-Delgado, Ainhoa González-Luis, Juan F. Navarro-González
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionKlotho protein is predominantly expressed in the kidneys and has also been detected in vascular tissue and peripheral blood circulating cells to a lesser extent. Carotid artery intima-media thickness (CIMT) burden, a marker of subclinical
Externí odkaz:
https://doaj.org/article/8ed93f83e8a44ab28490a75d82c0369c
Autor:
Ernesto Martín-Núñez, Atteneri Pérez-Castro, Víctor G. Tagua, Carolina Hernández-Carballo, Carla Ferri, Nayra Pérez-Delgado, Sergio Rodríguez-Ramos, Purificación Cerro-López, Ángel López-Castillo, Alejandro Delgado-Molinos, Victoria Castro López-Tarruella, Miguel A. Arévalo-Gómez, Ainhoa González-Luis, Alberto Martín-Olivera, Carmen Chaxiraxi Morales-Estévez, Carmen Mora-Fernández, Javier Donate-Correa, Juan F. Navarro-González
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Cardiovascular disease is the leading cause of death worldwide. New therapeutic strategies are aimed to modulate the athero-inflammatory process that partially orchestrates underlying vascular damage. Peripheral blood circulating cells inclu
Externí odkaz:
https://doaj.org/article/a434860e3ce947758d935bebe722e76c
Autor:
Lara Matilla, Ernesto Martín-Núñez, Mattie Garaikoetxea, Adela Navarro, Julieta Anabela Vico, Vanessa Arrieta, Amaia García-Peña, Amaya Fernández-Celis, Alicia Gainza, Virginia Álvarez, Rafael Sádaba, Natalia López-Andrés, Eva Jover
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
ObjectiveWe aim to analyze sex-related differences in angiogenesis and lymphangiogenesis in aortic valves (AVs) and valve interstitial cells (VICs) from aortic stenosis (AS) patients.Approach and ResultsTotally 230 patients (59% men) with severe AS u
Externí odkaz:
https://doaj.org/article/f4796e80063d4da49b3ad0e3e8e85ea1
Autor:
Javier Donate-Correa, Carla M. Ferri, Ernesto Martín-Núñez, Nayra Pérez-Delgado, Ainhoa González-Luis, Carmen Mora-Fernández, Juan F. Navarro-González
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Chronic kidney disease (CKD) has been associated with a higher risk of cardiovascular disease (CVD). CKD patients present a decrease in the levels of the protein Klotho that accompanies the decrease in kidney function. This protein has been
Externí odkaz:
https://doaj.org/article/a9ea4b5ddcc44e2f8897e955395cf614
Autor:
Rosa Pérez-Morales, Javier Donate-Correa, Ernesto Martín-Núñez, Nayra Pérez-Delgado, Carla Ferri, Aurora López-Montes, Alejandro Jiménez-Sosa, Juan Francisco Navarro-González
Publikováno v:
Renal Failure, Vol 43, Iss 1, Pp 821-829 (2021)
Background Overhydration is a predictor of mortality in hemodialysis (HD) patients. Bioimpedance spectroscopy (BIS) is used to determine the body composition. Extracellular Water/Total Body Water (ECW/TBW) ratio has been proposed to predict mortality
Externí odkaz:
https://doaj.org/article/f01bee8b6e3c4c43b33f6eeb3481412b