Zobrazeno 1 - 10 of 64 pro vyhledávání: '"Ernesto Gil Deza"'
1
Akademický článek
Blocking soluble TNFα sensitizes HER2-positive breast cancer to trastuzumab through MUC4 downregulation and subverts immunosuppression
Autor: Sofia Bruni, Florencia L Mauro, Cecilia J Proietti, Rosalia I Cordo-Russo, Martin A Rivas, Gloria Inurrigarro, Agustina Dupont, Dario Rocha, Elmer A Fernández, Ernesto Gil Deza, Daniel Lopez Della Vecchia, Sabrina Barchuk, Silvina Figurelli, David Lasso, Adrián D Friedrich, María C Santilli, María V Regge, Gabriel Lebersztein, Claudio Levit, Fabiana Anfuso, Teresa Castiglione, Patricia V Elizalde, Maria F Mercogliano, Roxana Schillaci
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 11, Iss 3 (2023)
Background The success of HER2-positive (HER2+) breast cancer treatment with trastuzumab, an antibody that targets HER2, relies on immune response. We demonstrated that TNFα induces mucin 4 (MUC4) expression, which shields the trastuzumab epitope on
Externí odkaz: https://doaj.org/article/260a8bffb8ab415c8e86847e61a3c8b1
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2
Akademický článek
Invasive micropapillary carcinoma of the breast overexpresses MUC4 and is associated with poor outcome to adjuvant trastuzumab in HER2-positive breast cancer
Autor: María F. Mercogliano, Gloria Inurrigarro, Mara De Martino, Leandro Venturutti, Martín A. Rivas, Rosalía Cordo-Russo, Cecilia J. Proietti, Elmer A. Fernández, Isabel Frahm, Sabrina Barchuk, Daniel H. Allemand, Silvina Figurelli, Ernesto Gil Deza, Sandra Ares, Felipe G. Gercovich, Eduardo Cortese, Matías Amasino, Pablo Guzmán, Juan C. Roa, Patricia V. Elizalde, Roxana Schillaci
Publikováno v: BMC Cancer, Vol 17, Iss 1, Pp 1-8 (2017)
Abstract Background Invasive micropapillary carcinoma of the breast (IMPC) is a histological tumor variant that occurs with low frequency characterized by an inside-out formation of tumor clusters with a pseudopapillary arrangement. IMPC is an aggres
Externí odkaz: https://doaj.org/article/58b71ec24f974724a0c1d23b8fb44294
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3
Akademický článek
Evaluación de las necesidades de los pacientes respecto a la información y los cuidados médicos tras el diagnóstico de cáncer
Autor: Ernesto Gil Deza, Daniela Gercovich, Eduardo Morgenfeld, Flavio Tognelli, Gastón Martín Reinas, Pablo López, Mónica Montiel, Carlos García Gerardi, Edgardo Rivarola, Felipe Gustavo Gercovich
Publikováno v: Psicooncologia, Vol 11, Iss 2-3, Pp 389-401 (2014)
Objetivo: Estudiar las necesidades de los pacientes oncológicos sobre la información referida a su enfermedad y los cuidados al final de la vida. Métodos: 820 pacientes participaron de una encuesta sobre diagnóstico, pronóstico, eficacia y toxic
Externí odkaz: https://doaj.org/article/dbf9d35e50a242cda9a20409a1a44c10
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4
Akademický článek
The role of psychological distress in the relationship between illness perception and quality of life in patients with breast cancer
Autor: Daniela Gercovich, Pablo Luis López, Diego Bortolato, Patricia Margiolakis, Mirta Morgenfeld, Laura Rosell, Ernesto Gil Deza
Publikováno v: Psicooncologia, Vol 9, Iss 2-3, Pp 403-414 (2013)
Objective: To evaluate the associations between the illness perception dimensions and quality of life, assessing the modulatory role of psychological distress in patients with breast cancer, identifying which of these dimensions explained further var
Externí odkaz: https://doaj.org/article/db93325ca4554875a155849ea5008272
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