Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Ernesto Cota"'
Autor:
Cyril Dian, Inmaculada Pérez-Dorado, Frédéric Rivière, Thomas Asensio, Pierre Legrand, Markus Ritzefeld, Mengjie Shen, Ernesto Cota, Thierry Meinnel, Edward W. Tate, Carmela Giglione
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
N-terminal glycine myristoyl transferases (NMTs) catalyse the myristoylation of eukaryotic proteins. Here, the authors provide insights into the catalytic mechanism of NMTs by determining the crystal structures of human NMT1 in complex with reactive
Externí odkaz:
https://doaj.org/article/1d7d6b525886413db95bc8b3e99c1d00
Autor:
Helen G Pennington, Rhian Jones, Seomun Kwon, Giulia Bonciani, Hannah Thieron, Thomas Chandler, Peggy Luong, Sian Natasha Morgan, Michal Przydacz, Tolga Bozkurt, Sarah Bowden, Melanie Craze, Emma J Wallington, James Garnett, Mark Kwaaitaal, Ralph Panstruga, Ernesto Cota, Pietro D Spanu
Publikováno v:
PLoS Pathogens, Vol 15, Iss 3, p e1007620 (2019)
The biotrophic fungal pathogen Blumeria graminis causes the powdery mildew disease of cereals and grasses. We present the first crystal structure of a B. graminis effector of pathogenicity (CSEP0064/BEC1054), demonstrating it has a ribonuclease (RNas
Externí odkaz:
https://doaj.org/article/e8d99496804c458fa00d52bf2f4e190f
Autor:
Andrea A Berry, Yi Yang, Natalia Pakharukova, James A Garnett, Wei-chao Lee, Ernesto Cota, Jan Marchant, Saumendra Roy, Minna Tuittila, Bing Liu, Keith G Inman, Fernando Ruiz-Perez, Inacio Mandomando, James P Nataro, Anton V Zavialov, Steve Matthews
Publikováno v:
PLoS Pathogens, Vol 10, Iss 9, p e1004404 (2014)
Enteroaggregative Escherichia coli (EAEC) is a leading cause of acute and persistent diarrhea worldwide. A recently emerged Shiga-toxin-producing strain of EAEC resulted in significant mortality and morbidity due to progressive development of hemolyt
Externí odkaz:
https://doaj.org/article/2fd6baa77f094eb08a903919a04007e9
Publikováno v:
ACS Chemical Biology
Malaria remains an endemic tropical disease, and the emergence of Plasmodium falciparum parasites resistant to current front-line medicines means that new therapeutic targets are required. The Plasmodium glideosome is a multiprotein complex thought t
Publikováno v:
Physical Review A. 104
We study the geometric Uhlmann phase of entangled mixed states in a composite system made of two coupled spin-$\frac 1 2$ particles with a magnetic field acting on one of them. Within a depolarizing channel setup, an exact analytical expression for s
Autor:
Peter A. D. Wellham, Ernesto Cota, Rachel Greenhill, Michal Przydacz, Tia Salter, Pietro Spanu, Maya S. Bruderer, Helen G. Pennington, Gerard Belmans, Rhian Jones
Publikováno v:
Plant Physiol
Jasmonate-induced protein 60 (JIP60) is a ribosome-inactivating protein (RIP) from barley (Hordeum vulgare) and is involved in the plant immune response dependent on jasmonate hormones. Here, we demonstrate in Nicotiana benthamiana that transient exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aefa7d40294f800606c46d071b7aff2
https://europepmc.org/articles/PMC7210648/
https://europepmc.org/articles/PMC7210648/
Autor:
Mengjie Shen, Cyril Dian, Ernesto Cota, Carmela Giglione, Pierre Legrand, Frédéric Rivière, Edward W. Tate, Thierry Meinnel, Thomas Asensio, Inmaculada Pérez-Dorado, Markus Ritzefeld
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications
'Nature Communications ', vol: 11, pages: 1132-1-1132-15 (2020)
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.1132. ⟨10.1038/s41467-020-14847-3⟩
Nature Communications, 2020, 11 (1), pp.1132. ⟨10.1038/s41467-020-14847-3⟩
Nature Communications
'Nature Communications ', vol: 11, pages: 1132-1-1132-15 (2020)
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.1132. ⟨10.1038/s41467-020-14847-3⟩
Nature Communications, 2020, 11 (1), pp.1132. ⟨10.1038/s41467-020-14847-3⟩
The promising drug target N-myristoyltransferase (NMT) catalyses an essential protein modification thought to occur exclusively at N-terminal glycines (Gly). Here, we present high-resolution human NMT1 structures co-crystallised with reactive cognate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e1596060677e5c95c6f14ce070e70f8
http://hdl.handle.net/10044/1/77568
http://hdl.handle.net/10044/1/77568
Autor:
Edward W. Tate, Inmaculada Pérez-Dorado, James W. Murray, Randy J. Read, Mostafa Jamshidiha, Ernesto Cota
Publikováno v:
Acta Crystallographica. Section D, Structural Biology
The solution of a structure of human Rab27a suffering from severe anisotropy and translational noncrystallographic symmetry was aided by identifying diffraction measurements with low information content.
Data pathologies caused by effects such a
Data pathologies caused by effects such a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09bb5613e5add29eb8e2cc6cf07b9bf1
https://www.repository.cam.ac.uk/handle/1810/288521
https://www.repository.cam.ac.uk/handle/1810/288521
Autor:
Sarah Bowden, Pietro Spanu, Peggy Luong, Thomas Chandler, Ralph Panstruga, Seomun Kwon, Ernesto Cota, Giulia Bonciani, Michal Przydacz, Emma J. Wallington, Hannah Thieron, Sian Natasha Morgan, Helen G. Pennington, Mark Kwaaitaal, James A. Garnett, Rhian Jones, Melanie Craze, Tolga O. Bozkurt
Publikováno v:
PLoS Pathogens, Vol 15, Iss 3, p e1007620 (2019)
PLoS pathogens 15(3), e1007620 (2019). doi:10.1371/journal.ppat.1007620
PLoS pathogens 15(3), e1007620 (2019). doi:10.1371/journal.ppat.1007620
PLoS pathogens 15(3), e1007620 - (2019). doi:10.1371/journal.ppat.1007620
Published by PLoS, Lawrence, Kan.
Published by PLoS, Lawrence, Kan.
Autor:
Masooma, Rasheed, Mostafa, Jamshidiha, Rita, Puglisi, Robert, Yan, Ernesto, Cota, Annalisa, Pastore
Publikováno v:
The Febs Journal
Frataxins form an interesting family of iron‐binding proteins with an almost unique fold and are highly conserved from bacteria to primates. They have a pivotal role in iron–sulfur cluster biogenesis as regulators of the rates of cluster formatio