Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Ernesto Chico"'
Autor:
Héctor E Sánchez-Vargas, Diana D Alcalá-Galiano Morell, Patrick Fickers, Ernesto Chico, Luis B Ramos-Sánchez
Publikováno v:
Biotecnología Aplicada, Vol 32, Iss 3, Pp 3301-3306 (2015)
Externí odkaz:
https://doaj.org/article/bb67983416e84f0ab81f0638ef15555a
Publikováno v:
Biotecnología Aplicada, Vol 29, Iss 4, Pp 246-252
Mathematical modeling of metabolism meets several important applications in the context of bioprocess engineering, such as the interpretation of cell physiology. Metabolic Flux Analysis, one of the tools of this discipline, was used in the present wo
Externí odkaz:
https://doaj.org/article/3f1f1c0286164af5b8a22bbd7538f2a3
Publikováno v:
Biotechnology Progress. 28:1491-1498
In the present work, the main fluid flow features inside a rotating cylindrical filtration (RCF) system used as external cell retention device for animal cell perfusion processes were investigated using particle image velocimetry (PIV). The motivatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abd7d7da6d81c0c80f9de3345d0c0016
https://doi.org/10.1002/btpr.1618
https://doi.org/10.1002/btpr.1618
Publikováno v:
Cytotechnology. 61:55-64
In the present work Computational Fluid Dynamics (CFD) was used to study the flow field and particle dynamics in an internal spin-filter (SF) bioreactor system. Evidence of a radial exchange flow through the filter mesh was detected, with a magnitude
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb05e0f0df31ca9fc51f11a0a92869f6
https://doi.org/10.1007/s10616-009-9242-8
https://doi.org/10.1007/s10616-009-9242-8
Autor:
Ricardo de Andrade Medronho, Edel Martínez, Alvio Figueredo-Cardero, Ernesto Chico, Leda R. Castilho
Publikováno v:
Biotechnology progress. 30(5)
The particle and fluid dynamics in a rotating cylindrical filtration (RCF) system used for animal cell retention in perfusion processes was studied. A validated CFD model was used and the results gave numerical evidence of phenomena that had been ear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::429aff6a9afe2b8604202faac8f0159e
https://pubmed.ncbi.nlm.nih.gov/25059206
https://pubmed.ncbi.nlm.nih.gov/25059206
Autor:
Ernesto Chico, Volker Jäger
Publikováno v:
Biotechnology and Bioengineering. 70:574-586
The impact of different cultivation-infection strategies on the productivity of baculovirus-infected BTI-Tn-5B1-4 (High Five) cells was investigated. Using beta-trace protein as the recombinant glycoprotein, the effects of multiplicity of infection (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c71e8eeeee5ce30fa04f96c410bec77
https://doi.org/10.1002/1097-0290(20001205)70:5<574::aid-bit12>3.0.co
https://doi.org/10.1002/1097-0290(20001205)70:5<574::aid-bit12>3.0.co
Publikováno v:
Cells and Culture ISBN: 9789048134182
Continuous culture mode has not been used usually as a production choice for the manufacturing of biopharmaceuticals from animal cell culture. Instead, fed batch and perfusion are generally used. However for the production of unstable molecules, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbc5dfa37e91222013c4c35cf9504e09
https://doi.org/10.1007/978-90-481-3419-9_44
https://doi.org/10.1007/978-90-481-3419-9_44
Publikováno v:
Cells and Culture ISBN: 9789048134182
In this work, simulations of a spin-filter bioreactor were carried out using computational fluid dynamics (CFD). Bi-directional radial exchange of fluid through the filter mesh and lateral migration were observed in the simulations. The fluid exchang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a64018ed9757c1c08358192ab270a36
https://doi.org/10.1007/978-90-481-3419-9_40
https://doi.org/10.1007/978-90-481-3419-9_40
Autor:
Volker Jäger, Ernesto Chico
Publikováno v:
New Developments and New Applications in Animal Cell Technology ISBN: 0792350162
We have found that the cell size distributions measured by a CASYTM cell counter can be used to follow the infection process of various insect cell lines. After infection, cell size deviates from the typical distribution of exponentially growing cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::745b188ebd148f861a20f7fa9f7a79d2
https://doi.org/10.1007/0-306-46860-3_59
https://doi.org/10.1007/0-306-46860-3_59
Publikováno v:
ESACT Proceedings ISBN: 1402027915
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f02c22b1749a9f7e0eafcb023501aff
https://doi.org/10.1007/1-4020-3103-3_140
https://doi.org/10.1007/1-4020-3103-3_140