Zobrazeno 1 - 10
of 540
pro vyhledávání: '"Ernesto Canalis"'
Publikováno v:
Osteoarthritis and Cartilage Open, Vol 6, Iss 4, Pp 100528- (2024)
Objective: To further our understanding of the role of tumor necrosis factor (TNF)α on the inflammatory response in chondrocytes. Design: We explored the effects of TNFα on the transcriptome of epiphyseal chondrocytes from newborn C57BL/6 mice at t
Externí odkaz:
https://doaj.org/article/106197f5527e4491bbeb6c41005a7501
Akademický článek
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Publikováno v:
PLoS ONE, Vol 17, Iss 5 (2022)
Notch receptors are determinants of cell fate and function, and play an important role in the regulation of bone development and skeletal remodeling. Lateral Meningocele Syndrome (LMS) is a monogenic disorder associated with NOTCH3 pathogenic variant
Externí odkaz:
https://doaj.org/article/905ef0c0df8b4b55a38bde93f5dca455
Autor:
E, Canalis
Publikováno v:
Endocrine reviews. 17(4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4ac7228ef7c95c7a9f12dc18905f2be4
https://pubmed.ncbi.nlm.nih.gov/8854056
https://pubmed.ncbi.nlm.nih.gov/8854056
Autor:
Song Ho Chang, Daisuke Mori, Hiroshi Kobayashi, Yoshifumi Mori, Hideki Nakamoto, Keita Okada, Yuki Taniguchi, Shurei Sugita, Fumiko Yano, Ung-il Chung, Joo-ri Kim-Kaneyama, Motoko Yanagita, Aris Economides, Ernesto Canalis, Di Chen, Sakae Tanaka, Taku Saito
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Excessive mechanical stress promotes the development of osteoarthritis. Here Chang et al. identify gremlin-1 as a factor expressed in chondrocytes in response to mechanical stress, and contributing to osteoarthritis via activation of the NF-κB pathw
Externí odkaz:
https://doaj.org/article/89ba19c2f9a9477294c478b865fc68cf
Autor:
Ernesto Canalis
Publikováno v:
Frontiers in Genetics, Vol 11 (2021)
Notch (Notch1 through 4) are transmembrane receptors that determine cell differentiation and function, and are activated following interactions with ligands of the Jagged and Delta-like families. Notch has been established as a signaling pathway that
Externí odkaz:
https://doaj.org/article/eb847ff0af1345689d2518a9d9370cb9
Publikováno v:
Nature Reviews Endocrinology. 18:353-365
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c3e1cfaf0e3373d679cb06b66282eb9
https://doi.org/10.1038/s41574-022-00649-8
https://doi.org/10.1038/s41574-022-00649-8
Akademický článek
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Publikováno v:
Bone. 172:116760
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d522cff557267afd7ccae6ceaf82cb2
https://doi.org/10.1016/j.bone.2023.116760
https://doi.org/10.1016/j.bone.2023.116760
Publikováno v:
J Cell Physiol
The present study defines the function of nuclear factor of activated T cells (NFAT)c1 and NFATc2 in osteoblast function in vivo and in vitro. Nfatc1loxP/loxP , Nfatc2loxP/loxP , and Nfatc1loxP/loxP ;Nfatc2loxP/loxP conditional mice were mated with B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8ddefdc6655b0a67ec459a49e0f00ff
https://doi.org/10.1002/jcp.29696
https://doi.org/10.1002/jcp.29696