Zobrazeno 1 - 10
of 205
pro vyhledávání: '"Ernestina, Schipani"'
Autor:
Aaron Warren, Ryan M. Porter, Olivia Reyes-Castro, Md Mohsin Ali, Adriana Marques-Carvalho, Ha-Neui Kim, Landon B. Gatrell, Ernestina Schipani, Intawat Nookaew, Charles A. O’Brien, Roy Morello, Maria Almeida
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract NAD is an essential co-factor for cellular energy metabolism and multiple other processes. Systemic NAD+ deficiency has been implicated in skeletal deformities during development in both humans and mice. NAD levels are maintained by multiple
Externí odkaz:
https://doaj.org/article/31b21a11cd5347c8bd0682ffb5225850
Autor:
Ernestina Schipani, Geert Carmeliet
Publikováno v:
Bone Reports, Vol 19, Iss , Pp 101719- (2023)
Externí odkaz:
https://doaj.org/article/5416d2b5c587476fa7722a98d3410ff0
Autor:
Monica Reyes, Damla Firat, Patrick Hanna, Mohd Khan, Michael Bruce, Maria Shvedova, Tatsuya Kobayashi, Ernestina Schipani, Thomas J. Gardella, Harald Jüppner
Publikováno v:
JBMR Plus, Vol 7, Iss 10, Pp n/a-n/a (2023)
Abstract Activating parathyroid hormone (PTH)/PTH‐related Peptide (PTHrP) receptor (PTH1R) mutations causes Jansen's metaphyseal chondrodysplasia (JMC), a rare disease characterized by growth plate abnormalities, short stature, and PTH‐independen
Externí odkaz:
https://doaj.org/article/9644361ce3b2494ab05f44e05b127542
Publikováno v:
Bone Reports, Vol 18, Iss , Pp 101688- (2023)
The role of energy metabolism in bone cells is an active field of investigation. Bone cells are metabolically very active and require high levels of energy in the form of adenosine triphosphate (ATP) to support their function. ATP is generated in the
Externí odkaz:
https://doaj.org/article/b7b8d01fb39a45cc810d7b82adac6efe
Autor:
Jussi‐Pekka Tolonen, Antti M Salo, Mikko Finnilä, Ellinoora Aro, Emma Karjalainen, Veli‐Pekka Ronkainen, Kati Drushinin, Christophe Merceron, Valerio Izzi, Ernestina Schipani, Johanna Myllyharju
Publikováno v:
JBMR Plus, Vol 6, Iss 6, Pp n/a-n/a (2022)
ABSTRACT Proper deposition of the extracellular matrix and its major components, the collagens, is essential for endochondral ossification and bone mass accrual. Collagen prolyl 4‐hydroxylases (C‐P4Hs) hydroxylate proline residues in the ‐X‐P
Externí odkaz:
https://doaj.org/article/e831618620d0402c825f51dbec21c83d
Autor:
Veronica Mendoza-Reinoso, Patricia M. Schnepp, Dah Youn Baek, John R. Rubin, Ernestina Schipani, Evan T. Keller, Laurie K. McCauley, Hernan Roca
Publikováno v:
Cells, Vol 11, Iss 23, p 3712 (2022)
The clearance of apoptotic cancer cells by macrophages, known as efferocytosis, fuels the bone-metastatic growth of prostate cancer cells via pro-inflammatory and immunosuppressive processes. However, the exact molecular mechanisms remain unclear. In
Externí odkaz:
https://doaj.org/article/5b0d4efb334b440bb74d6091d6258d3b
Autor:
Chun Wang, Can-Xin Xu, Yael Alippe, Chao Qu, Jianqiu Xiao, Ernestina Schipani, Roberto Civitelli, Yousef Abu-Amer, Gabriel Mbalaviele
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Skeletal complications are common features of neonatal-onset multisystem inflammatory disease (NOMID), a disorder caused by NLRP3-activating mutations. NOMID mice in which NLRP3 is activated globally exhibit several characteristics of the hu
Externí odkaz:
https://doaj.org/article/13f4d71f788e4c60923f5962ac917d93
Autor:
Melissa L. Fishel, Mark R. Kelley, Mircea Ivan, Murray Korc, Claudiu T. Supuran, Fabrizio Carta, Ernestina Schipani, Nicholas Zyromski, Zhangsheng Yu, Yan Tong, Yanlin Jiang, Safi Shahda, Meihua Luo, Michelle Grimard, Derek P. Logsdon
CA9 protein levels are increased under hypoxia, but APE1 levels are not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::501fc94b2895bac86b1e0d7275a71fa4
https://doi.org/10.1158/1535-7163.22506472
https://doi.org/10.1158/1535-7163.22506472
Autor:
Melissa L. Fishel, Mark R. Kelley, Mircea Ivan, Murray Korc, Claudiu T. Supuran, Fabrizio Carta, Ernestina Schipani, Nicholas Zyromski, Zhangsheng Yu, Yan Tong, Yanlin Jiang, Safi Shahda, Meihua Luo, Michelle Grimard, Derek P. Logsdon
APE1/Ref-1 protein expression affects CA9 mRNA levels in additional PDAC cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9debadbdc4fb1642fd4859d3d129d999
https://doi.org/10.1158/1535-7163.22506475.v1
https://doi.org/10.1158/1535-7163.22506475.v1
Autor:
Melissa L. Fishel, Mark R. Kelley, Mircea Ivan, Murray Korc, Claudiu T. Supuran, Fabrizio Carta, Ernestina Schipani, Nicholas Zyromski, Zhangsheng Yu, Yan Tong, Yanlin Jiang, Safi Shahda, Meihua Luo, Michelle Grimard, Derek P. Logsdon
Confirmation of HIF-1 deletion in MEF cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc2b0e87ad6a11da1ec3801649baf25
https://doi.org/10.1158/1535-7163.22506487
https://doi.org/10.1158/1535-7163.22506487