Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Ernest Winocour"'
Publikováno v:
Journal of Virology. 74:6213-6216
The DNA sequence motifs which direct adeno-associated virus type 2 site-specific integration are being investigated using a shuttle vector, propagated as a stable episome in cultured cell lines, as the target for integration. Previously, we reported
Publikováno v:
Proceedings of the National Academy of Sciences. 91:10039-10043
Different regions of an 8.2-kb cloned DNA segment containing the target for adeno-associated virus (AAV) integration in human chromosome 19q13-3-qter (AAVS1 locus) were subcloned in an Epstein-Barr virus-based shuttle vector and propagated as episome
Autor:
Maxine F. Singer, Ernest Winocour
Publikováno v:
Virology. 412(2)
The available monkey genomic data banks were examined in order to determine the chromosomal locations of the host DNA inserts in 8 host-substituted SV40 variant DNAs. Five of the 8 variants contained more than one linked monkey DNA insert per tandem
Publikováno v:
The EMBO journal. 16(19)
High mobility group protein 1 (HMG1) is an abundant non-histone chromosomal protein which plays a role in several nuclear events involving DNA. Here we demonstrate that HMG1 physically interacts with the human adeno-associated virus (AAV) Rep protein
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 93(15)
The adeno-associated virus (AAV) genome integrates site specifically into a defined region of human chromosome 19 (termed AAVS1). Using a functional assay for AAV integration into AAVS1 DNA propagated as an episome, we obtained evidence that a 33-nuc
Autor:
Tamar Koch, Eitan Shauliana, Leopold Puzis, Bernard Danovitch, Sara Etkin, Shulamit Karby, Ernest Winocour, Sara Lavi, Ella Mendelson
Publikováno v:
Virology. 190(1)
The adeno-associated virus (AAV) rep gene encodes a series of overlapping, multifunctional, nonstructural proteins (Rep proteins) which regulate the viral life cycle and which are also capable of trans-regulating nonviral gene expressions (reviewed i
Publikováno v:
Virology. 134:125-137
Recombination between simian virus 40 (SV40) and adeno-associated virus (AAV) has been detected, by infectious center in situ plaque hybridization procedures, after both DNA contransfection and virion coinfection of monkey BSC-1 cells. The number of
Publikováno v:
Virology. 94:82-94
The transcription of a cloned host-substituted SV40 genome of defined structure was studied in cells coinfected with wild-type virus and in in vitro reactions with Sarkosyl nuclear extracts (transcription complex preparations) of the coinfected cells
Publikováno v:
Virology. 80:225-228
Monkey cells were exposed to homologous interferon both before and at different times after infection with simian virus 40 (SV40). It was found that exposure of the infected cells to interferon after the onset of viral DNA synthesis inhibited subsequ
Publikováno v:
Proceedings of the National Academy of Sciences. 74:457-461
Simian virus 40 (SV40) mRNA was isolated by hybridization of cytoplasmic RNA, from SV40-infected BS-C-1 monkey cells early in lytic infection, to SV40 DNA immobilized on Sepharose. The early viral mRNA, when added to a wheat-germ translation system,