Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Ernest S. Kim"'
Autor:
Rebeccah J. Luu, B. Christopher Hoefler, Ashley L. Gard, Casey R. Ritenour, Miles T. Rogers, Ernest S. Kim, Jonathan R. Coppeta, Brian P. Cain, Brett C. Isenberg, Hesham Azizgolshani, Oscar R. Fajardo-Ramirez, Guillermo García-Cardeña, Matthew P. Lech, Lindsay Tomlinson, Joseph L. Charest, Corin Williams
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Background: Tissue fibrosis is a major healthcare burden that affects various organs in the body for which no effective treatments exist. An underlying, emerging theme across organs and tissue types at early stages of fibrosis is the activation of pe
Externí odkaz:
https://doaj.org/article/8223c1e9f8d84ea8861ab8c9956e14d2
Autor:
Michaela Welch, Deborah A. Flusberg, Peter Hsi, Nerses J. Haroutunian, Jose A. Santos, Ernest S. Kim, Stacey Markovic, Jonathan R. Coppeta, Charles A. Lissandrello, Jenna L. Balestrini, Vishal Tandon
Publikováno v:
Advanced Materials Technologies.
Autor:
Athanasios Peppas, T J Mulhern, James Truslow, Joseph L. Charest, Alex Markoski, Derek Solt, James C. Hsiao, Christopher Dibiasio, Sivaprasad Sukavaneshvar, Jeffrey T. Borenstein, Diana J. Lewis, Daniel I. Harjes, Jose A. Santos, Daniel A. Lang, Alla A. Gimbel, Ernest S. Kim
Publikováno v:
Lab on a Chip. 21:4637-4651
Microfluidic lab-on-a-chip devices are changing the way that in vitro diagnostics and drug development are conducted, based on the increased precision, miniaturization and efficiency of these systems relative to prior methods. However, the full poten
Autor:
Christian Wells, Meinhold Mitchell W, Ernest S. Kim, Peter Lewis, Jeffery B. DeLisio, Caprice Gray, David Hagerstrom, Daniela A. Torres
Publikováno v:
Journal of Microelectronics and Electronic Packaging. 17:52-58
A tool has been developed that supports a novel microelectronic integration paradigm whereby interconnects between components are directly established by way of micro-coax wirebonds. A near term use-case of the tool is to facilitate rapid prototyping
Autor:
T J Mulhern, Ashley L. Gard, Brett C. Isenberg, Ernest S. Kim, Kelly Tan, Vishal Tandon, Shyam Sundhar Bale, Miles Rogers, Jonathan R. Coppeta, J C de Souza, B C Hoefler, A Zorn, K B Baldwin, E L Wiellette, Else M. Vedula, Matthew P. Lech, Joseph L. Charest, Louis B. Kratchman, A Patterson, Philip M. Keegan, Hesham Azizgolshani, Nerses J. Haroutunian, E E Marr, S H Kann, Corin Williams, B P Cain, R J Luu, T A Petrie
Publikováno v:
Lab on a chip. 21(8)
Drug development suffers from a lack of predictive and human-relevant in vitro models. Organ-on-chip (OOC) technology provides advanced culture capabilities to generate physiologically appropriate, human-based tissue in vitro, therefore providing a r
Autor:
Thomas F. Risoleo, Jeffrey T. Borenstein, Joseph N. Urban, Diana J. Lewis, James C. Hsiao, Alla A. Gimbel, Ernest S. Kim
Publikováno v:
Artificial Organs. 45
Advances in microfluidics technologies have spurred the development of a new generation of microfluidic respiratory assist devices, constructed using microfabrication techniques capable of producing microchannel dimensions similar to those found in h
Autor:
Patricia Swierk, Jose A. Santos, William Robberson, Mark F. Witinski, Beckett C. Colson, Louis B. Kratchman, Alexandra Z. Greenbaum, Joseph L. Hollmann, Peter Miraglia, Melissa M. Sprachman, Harry L. Allen, Steven Tate, Kenneth A. Markoski, Anna-Marie Cook, Morgan G. Blevins, Sheila S. Hemami, Ernest S. Kim, Anna P. M. Michel, Vienna L. Mott, Ava A. LaRocca
Publikováno v:
Sensors (Basel, Switzerland)
Sensors, Vol 21, Iss 3532, p 3532 (2021)
Sensors, Vol 21, Iss 3532, p 3532 (2021)
Microplastics (MPs) have been found in aqueous environments ranging from rural ponds and lakes to the deep ocean. Despite the ubiquity of MPs, our ability to characterize MPs in the environment is limited by the lack of technologies for rapidly and a
Autor:
Daniel K. Freeman, Vienna L. Mott, Nerses J. Haroutunian, Jenna L. Balestrini, Vishal Tandon, Ernest S. Kim, Andrew Czarnecki, Charles A Lissandrello, Aaron G Stoddard, Michaela Welch, Peter Hsi, Jonathan R. Coppeta, Jordan P. Chesin, Jose A. Santos, Deborah A Flusberg
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Scientific Reports
Scientific Reports
Implementation of gene editing technologies such as CRISPR/Cas9 in the manufacture of novel cell-based therapeutics has the potential to enable highly-targeted, stable, and persistent genome modifications without the use of viral vectors. Electropora
Autor:
Nerses J. Haroutunian, Kelly Tan, Vishal Tandon, Else M. Vedula, Brett C. Isenberg, Philip M. Keegan, Louis B. Kratchman, Miles Rogers, Jonathan R. Coppeta, Shyam Sundhar Bale, Hesham Azizgolshani, Veronica Newlin, Stephanie Golmon, B P Cain, Mingjian Lu, Ernest S. Kim, Joseph L. Charest, James R. Gosset, Abigail J Patterson
Publikováno v:
Lab on a chip. 20(19)
Correction for ‘A high-throughput microfluidic microphysiological system (PREDICT-96) to recapitulate hepatocyte function in dynamic, re-circulating flow conditions’ by Kelly Tan et al., Lab Chip, 2019, 19, 1556–1566, DOI: 10.1039/C8LC01262H.
Autor:
Rachelle Prantil-Baun, Jonathan R. Coppeta, T J Mulhern, James C. Comolli, Ernest S. Kim, Brett C. Isenberg, Jeffrey T. Borenstein, Abigail June Spencer, Amanda R. Lever, Mark J. Mescher
Publikováno v:
Lab on a Chip. 17:134-144
The drug development pipeline is severely limited by a lack of reliable tools for prediction of human clinical safety and efficacy profiles for compounds at the pre-clinical stage. Here we present the design and implementation of a platform technolog