Zobrazeno 1 - 1
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pro vyhledávání: '"Ernest McEachern"'
Autor:
Renato Skerlj, Gary Bridger, Yuanxi Zhou, Elyse Bourque, Ernest McEachern, Jonathan Langille, Curtis Harwig, Duane Veale, Wen Yang, Tongshong Li, Yongbao Zhu, Michael Bey, Ian Baird, Michael Sartori, Markus Metz, Renee Mosi, Kim Nelson, Veronique Bodart, Rebecca Wong, Simon Fricker, Ron Mac Farland, Dana Huskens, Dominique Schols
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 21:6950-6954
A series of CCR5 antagonists were optimized for potent inhibition of R5 HIV-1 replication in peripheral blood mononuclear cells. Compounds that met acceptable ADME criteria, selectivity, human plasma protein binding, potency shift in the presence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe8c7c65ea6806cdd761d65d01e7a8e4
https://doi.org/10.1016/j.bmcl.2011.09.133
https://doi.org/10.1016/j.bmcl.2011.09.133
