Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Ernest L. Raymond"'
Autor:
Kristine Nguyen, Yu Wang, Guangping Sun, Eric M. Wier, Alexander C. Klimowicz, Alina I. Marusina, Jack C. Otterson, Joshua D. Milner, Lee Ann T. Marcello, Roger V. Ortines, Alexander A. Merleev, George Denny, Dustin Dikeman, Jay S. Fine, Qi Liu, Emily Zhang, Emanual Michael Maverakis, Lloyd S. Miller, Christine Youn, Garrett J. Patrick, Yan Zhang, Martin P. Alphonse, Haiyun Liu, Momina Mazhar, Danh C. Do, Meera Ramanujam, Nathan K. Archer, Advaitaa Ravipati, Ernest L. Raymond, Peisong Gao, Sabrina J. Nolan, Robert J. Miller, Diane Mierz, Gary O. Caviness, Raphaela Goldbach-Mansky, Carly A. Dillen, Luis A. Garza
Publikováno v:
J Clin Invest
The Journal of clinical investigation, vol 131, iss 5
The Journal of clinical investigation, vol 131, iss 5
IgE induced by type 2 immune responses in atopic dermatitis is implicated in the progression of atopic dermatitis to other allergic diseases, including food allergies, allergic rhinitis, and asthma. However, the keratinocyte-derived signals that prom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3e1319c539f7f589bf052e9683f6253
https://doi.org/10.1172/jci143334
https://doi.org/10.1172/jci143334
Autor:
Giuseppe Campagna, Maurizio Mattei, Ernest L. Raymond, Alberto Signore, Rita Bonfiglio, Filippo Borri, Sara Fazi, Rosella Cicconi, Tanja Schönberger, Elena Bonanno, Manuel Scimeca, Andreas Wunder, Michela Varani, Filippo Galli
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 2028, p 2028 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 4
International Journal of Molecular Sciences
Volume 22
Issue 4
This study aims to develop a reliable and reproducible inflammatory bowel disease (IBD) murine model based on a careful spatial–temporal histological characterization. Secondary aims included extensive preclinical studies focused on the in situ exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e6ec52ca9311155b4ef5d33d62118a8
https://www.mdpi.com/1422-0067/22/4/2028
https://www.mdpi.com/1422-0067/22/4/2028
Autor:
Ernest L. Raymond, Ramona Schmid, Stefan O. Reber, Benjamin Strobel, Sudha Visvanathan, Kathrin Rieber, Wulf O. Böcher, Florian Gantner, Richard Vinisko, Mark Panzenbeck, Denis Delic, Dominik Langgartner, Christian T. Wohnhaas, Ines Jakob, Claudia Eisele, Franziska Wiech, Patrick Baum, Ivona Herichova, Eric Kaaru, Fei Shen, Marcel Rolser
Publikováno v:
Crohn's & Colitis 360
Background Short non-coding microRNAs (miRNAs) are involved in various cellular processes during disease progression of Crohn’s disease (CD) and remarkably stable in feces, which make them attractive biomarker candidates for reflecting intestinal i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36b60595d0e233932e0dd6b981dbc333
https://doi.org/10.1093/crocol/otaa003
https://doi.org/10.1093/crocol/otaa003
Autor:
Detlev Mennerich, Priyanka Gupta, Joseph R. Woska, Keith Canada, Danlin Yang, Michael D. Howell, Ernest L. Raymond, Rachel Kroe-Barrett, Gary O. Caviness, Rajkumar Ganesan, Simon Roberts, Kristopher Truncali, Su-Ellen Brown, Jennifer Ahlberg, M. Lamine Mbow, Jay S. Fine, Eliud Sepulveda, Sanjaya Singh, Perez Rocio K, Lee Frego, Kavita Jerath, Christine Grimaldi
Publikováno v:
mAbs
Deficiency of interleukin (IL)-36 receptor antagonist (DITRA) syndrome is a rare autosomal recessive disease caused by mutations in IL36RN. IL-36R is a cell surface receptor and a member of the IL1R family that is involved in inflammatory responses t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa1ac8d43b4da06b0ab9d7f67e62ebe3
https://doi.org/10.1080/19420862.2017.1353853
https://doi.org/10.1080/19420862.2017.1353853
Autor:
Siddhartha S. Saha, Ernest L. Raymond, Guanghui Yi, Joel A. Ybe, Gary O. Caviness, C. Cheng Kao, Rajkumar Ganesan, M. Lamine Mbow
Publikováno v:
Journal of Biological Chemistry. 291:16597-16609
Signal transduction by the IL-36 receptor (IL-36R) is linked to several human diseases. However, the structure and function of the IL-36R is not well understood. A molecular model of the IL-36R complex was generated and a cell-based reporter assay wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7a02f34b86f6f3000ebef67ec66017f
https://doi.org/10.1074/jbc.m116.723064
https://doi.org/10.1074/jbc.m116.723064
Autor:
Birgit Stierstorfer, Andreas Wunder, Eric Kaaru, Andrea Bianchi, Paresh Thakker, Anne Beltzer, Ernest L. Raymond, Detlef Stiller, Tanja Schönberger, Teresa Bluhmki
Publikováno v:
Inflammatory Bowel Diseases. 22:1286-1295
BACKGROUND Colonoscopy is the gold standard to diagnose and follow up the evolution of inflammatory bowel diseases. However, this technique can still present a risk of severe complications, a general discomfort in patients, and its diagnostic value i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c130085cbd52f83eac49a34bedbf7dca
https://doi.org/10.1097/mib.0000000000000755
https://doi.org/10.1097/mib.0000000000000755
Autor:
Kristina Scheibe, Ferdinand Knieling, M. Lamine Mbow, Michael Vieth, Timo Rath, Christina Kersten, Anabel Schmied, Ernest L. Raymond, Jing Claussen, Patrick Baum, Arif B. Ekici, Alexander C. Klimowicz, Clemens Neufert, Sebastian Meyer, Maximilian J. Waldner, Birgitta Carlé, Oliver Friedrich, Raja Atreya, Markus F. Neurath, Jie Zheng, George Kollias, Tatjana Primbs, Stefan Wirtz, Sebastian Schürmann
Publikováno v:
Gastroenterology. 156(4)
Background & Aims Intestinal fibrosis is a long-term complication in inflammatory bowel diseases (IBD) that frequently results in functional damage, bowel obstruction, and surgery. Interleukin (IL) 36 is a group of cytokines in the IL1 family with in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54d4e43e398b8f6bf2e80ae6f7630232
https://pubmed.ncbi.nlm.nih.gov/30776349
https://pubmed.ncbi.nlm.nih.gov/30776349
Autor:
Siddhartha S. Saha, Ernest L. Raymond, Joseph R. Woska, Christine Grimaldi, Gary O. Caviness, Su-Ellen Brown, Detlev Mennerich, M. Lamine Mbow, Divyendu Singh, Rajkumar Ganesan, C. Cheng Kao
Publikováno v:
Journal of Biological Chemistry. 290:23997-24006
Improper signaling of the IL-36 receptor (IL-36R), a member of the IL-1 receptor family, has been associated with various inflammation-associated diseases. However, the requirements for IL-36R signal transduction remain poorly characterized. This wor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68bf9e214d5116d5bc8c122c27d58b57
https://doi.org/10.1074/jbc.m115.653378
https://doi.org/10.1074/jbc.m115.653378
Autor:
C. Cheng Kao, Siddhartha S. Saha, Gary O. Caviness, Guanghui Yi, Ernest L. Raymond, M. Lamine Mbow
Publikováno v:
Journal of innate immunity. 10(1)
Signaling by the interleukin-36 receptor (IL-36R) is linked to inflammatory diseases such as psoriasis. However, the regulation of IL-36R signaling is poorly understood. Activation of IL-36R signaling in cultured cells results in an increased polyubi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e920d3328a0dcc6b99b8b6ea62b6d97
https://pubmed.ncbi.nlm.nih.gov/29176319
https://pubmed.ncbi.nlm.nih.gov/29176319
Autor:
Angela Berry, David S. Thomson, Doris Riether, Sabine Löbbe, Todd Bosanac, Andreas Ebneth, Diane Thome, Ernest L. Raymond, Daw-Tsun Shih, Renee Zindell, Mark J. Gemkow
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:1604-1609
Identification and optimization of two classes of CB2 selective agonists are described. A representative from each class is profiled in a murine model of inflammation and each shows similar efficacy to prednisolone upon oral dosing.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42f7d483f36825c54620336853737fe4
https://doi.org/10.1016/j.bmcl.2009.02.033
https://doi.org/10.1016/j.bmcl.2009.02.033