Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Ernest Groman"'
Publikováno v:
Frontiers in Public Health, Vol 11 (2023)
ObjectivePrevious analyses reported an unexpected decline of mean age of death of Austrian male lung cancer patients until 1996 and a subsequent turnaround of this epidemiological trend after the mid-1990s until 2007. In light of ongoing changes in s
Externí odkaz:
https://doaj.org/article/4653d10b77f349ee9e373d30e068decf
Autor:
Richard Felsinger, Ernest Groman
Publikováno v:
Frontiers in Public Health, Vol 10 (2022)
ObjectiveOnly 13% of the world's population are living in countries imposing appropriate tobacco tax-rates. This study aims to promote the implementation of price policy measures as a striking tobacco control strategy in Austria and to encourage othe
Externí odkaz:
https://doaj.org/article/993869a9c55b424f98b182fb8935aadf
Publikováno v:
Precision Nanomedicine, Vol 1, Iss 1 (2018)
Nanoparticles are recognized and cleared by Kupffer cells (KCs) in the liver. This process complicates the development of targeted nanoparticles because of significant reduction of number of nanoparticles that can reach target tissues. Macrophage sca
Externí odkaz:
https://doaj.org/article/8236a8cfbc554c85a462681461560b45
Autor:
Robert I. Scheinman, S. Moein Moghimi, Yue Li, Laura Saba, Dmitri Simberg, Ernest Groman, Nirmal K. Banda, Guankui Wang, Lynn Griffin
Publikováno v:
J Control Release
The complement system plays a key role in opsonization and immune clearance of engineered nanoparticles. Understanding the efficiency, inter-subject, and inter-strain differences of complement opsonization in preclinical species can help with transla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20b8db59ce44df334a4affb2a6c162e2
https://doi.org/10.1016/j.jconrel.2021.08.048
https://doi.org/10.1016/j.jconrel.2021.08.048
Autor:
Dmitri Simberg, Hanmant Gaikwad, Ernest Groman, Nirmal K. Banda, Geoffrey Gifford, Guankui Wang, Robert I. Scheinman, Laura Saba, Yue Li
Publikováno v:
Bioconjug Chem
Complement is one of the critical branches of innate immunity that determines the recognition of engineered nanoparticles by immune cells. Antibody-targeted iron oxide nanoparticles are a popular platform for magnetic separations, in vitro diagnostic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7b354050ad0acf77c3d4bc938267783
https://doi.org/10.1021/acs.bioconjchem.0c00342
https://doi.org/10.1021/acs.bioconjchem.0c00342
Autor:
David W. A. Bourne, Guankui Wang, Vivian P. Vu, Weston J. Smith, Hanmant Gaikwad, Dmitri Simberg, Ernest Groman
Publikováno v:
ACS Nano. 12:12523-12532
Long blood half-life is one of the advantages of antibodies over small molecule drugs. At the same time, prolonged half-life is a problem for imaging applications or in the case of antibody-induced toxicities. There is a substantial need for antidote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5810fe9be2865f1ad95ea6c72fe79e07
https://doi.org/10.1021/acsnano.8b07003
https://doi.org/10.1021/acsnano.8b07003
Autor:
Geoffrey Gifford, Dmitri Simberg, Laura Saba, Hanmant Gaikwad, Robert I. Scheinman, Yue Li, Ernest Groman, Nirmal K. Banda, Guankui Wang
Publikováno v:
Bioconjugate Chemistry. 32:2128-2128
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7676731a12c3d1e9ac2bf5eb966f7237
https://doi.org/10.1021/acs.bioconjchem.1c00396
https://doi.org/10.1021/acs.bioconjchem.1c00396
Autor:
Vivian P. Vu, Ernest Groman, Robert I. Scheinman, Halli Benasutti, Laura Saba, Guankui Wang, Dmitri Simberg
Publikováno v:
Bioconjugate Chemistry. 28:2747-2755
Opsonization (coating) of nanoparticles with complement C3 component is an important mechanism that triggers immune clearance and downstream anaphylactic and proinflammatory responses. The variability of complement C3 binding to nanoparticles in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e53c68c2b588dc7b727b0961107e605
https://doi.org/10.1021/acs.bioconjchem.7b00496
https://doi.org/10.1021/acs.bioconjchem.7b00496
Autor:
Ursula Kunze, Ernest Groman
Publikováno v:
Wiener Medizinische Wochenschrift. 169:203-214
Impfungen gehoren weltweit zu den zehn erfolgreichsten Praventionsmasnahmen. Wahrend Impfprogramme fur Kinder in Europa installiert sind, ist das Konzept der Erwachsenenimpfung nicht etabliert. Dabei sind Impfungen fur Erwachsene uberaus sinnvoll: di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::316c5ba19018ec77262c4af8c350a916
https://doi.org/10.1007/s10354-017-0598-7
https://doi.org/10.1007/s10354-017-0598-7
Autor:
Guankui Wang, S. Moein Moghimi, Donald S. Backos, V. Michael Holers, Dmitri Simberg, Nirmal K. Banda, Geoffrey Gifford, Robert I. Scheinman, Ernest Groman, Vivian P. Vu
Publikováno v:
J Control Release
Complement activation plays an important role in pharmacokinetic and performance of intravenously administered nanomedicines. Significant efforts have been directed toward engineering of nanosurfaces with low complement activation, but due to promisc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65df20e3c7d66e25be094c3027b96502
https://pubmed.ncbi.nlm.nih.gov/30974134
https://pubmed.ncbi.nlm.nih.gov/30974134