Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Ernest G. Nolen"'
Autor:
Ernest G. Nolen, Madison H. Powers, Andrew W. Thompson, Brynn D. Lewis, John M. Bennett, Yuqi M. Cao
Publikováno v:
Synlett : accounts and rapid communications in synthetic organic chemistry
A highly efficient synthesis of a β-vinylserine synthetic equivalent is reported that exploits the stereodirecting effect of the N-toluenesulfonamide in an anti-diastereoselective (8.5:1) vinyl Grignard addition to an analogue of Garner’s aldehyde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59c9d2509566050f4ec7741e70ec1a5b
http://europepmc.org/articles/PMC8341458
http://europepmc.org/articles/PMC8341458
Autor:
Marc, López-Cano, Ingrid, Filgaira, Ernest G, Nolen, Gisela, Cabré, Jordi, Hernando, Dilip K, Tosh, Kenneth A, Jacobson, Concepció, Soler, Francisco, Ciruela
Publikováno v:
Pharmacol Res
Psoriasis is a chronic and relapsing inflammatory skin disease lacking a cure that affects approximately 2% of the population. Defective keratinocyte proliferation and differentiation, and aberrant immune responses are major factors in its pathogenes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c06d69a7c1034ca500e43e46a496fec8
https://pubmed.ncbi.nlm.nih.gov/34157422
https://pubmed.ncbi.nlm.nih.gov/34157422
Autor:
Ernest G. Nolen, Jaume Taura, Lucia Squarcialupi, Jordi Hernando, Francisco Ciruela, Víctor Fernández-Dueñas, Gisela Cabré, Kenneth A. Jacobson, Marc López-Cano
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Universidad de Barcelona
Altres ajuts: Fundació la Marató de TV3 (Grant 20152031) G protein-coupled adenosine receptors are promising therapeutic targets for a wide range of neuropathological conditions, including Parkinson's disease (PD). However, the ubiquity of adenosin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cca40ecbe592835553e9e4dbb5c0b816
http://hdl.handle.net/2445/172324
http://hdl.handle.net/2445/172324
Publikováno v:
Synthetic Communications. 36:1707-1713
A short synthesis of orthogonally protected S,S-diaminopimelic acid, DAP, via a selective cross-metathesis between S-allyl glycine and S-vinyl glycine followed by hydrogenation is reported. By analogy, the S,S-diaminosuberic acid, DAS, is produced by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::639486aa4bffd984a4fcc8e4cf5a5f93
https://doi.org/10.1080/00397911.2006.10745071
https://doi.org/10.1080/00397911.2006.10745071
Publikováno v:
Tetrahedron Letters. 44:2449-2453
The Grubbs second generation ruthenium catalyst was employed for the cross metathesis between α- and β-C-allyl glycosides and suitably protected l-vinyl glycines to furnish olefinic products in 57–94% yields. Hydrogenation afforded the C-glycosyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c982bd257abafe90e8f343267304080d
https://doi.org/10.1016/s0040-4039(03)00350-2
https://doi.org/10.1016/s0040-4039(03)00350-2
Publikováno v:
Carbohydrate research. 396
Oct-2-enitols undergo a Pd 0 -mediated cyclization to produce C -vinyl α-gluco- and α-galactopyranosides, and C -vinyl β-mannopyranoside in good yield and with high stereoselectivity. While substrate control demonstrates a clear stereochemical pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::294b43e67c4766c0736bed6fb15e108d
https://pubmed.ncbi.nlm.nih.gov/25084508
https://pubmed.ncbi.nlm.nih.gov/25084508
Publikováno v:
The Journal of organic chemistry. 78(13)
The glycosylation of proteins, specifically installation of O-GlcNAc on Ser/Thr residues, is a dynamic control element for transcription repression, protein degradation, and nutrient sensing. To provide homogeneous and stable structures with this mot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0bfbbaa29d9144d2596bdafe6655d61
https://pubmed.ncbi.nlm.nih.gov/23767880
https://pubmed.ncbi.nlm.nih.gov/23767880
Autor:
Ryuichi Shirai, Duke M. Fitch, William M. Clark, Richard A. Hartz, Ernest G. Nolen, Amos B. Smith, Paul A. Sprengeler, M Ohta, Noritaka Chida, F. R. Blase
Publikováno v:
The Journal of Organic Chemistry. 60:7837-7848
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc08d1a7022a3ab1fef5da9e980b0899
https://doi.org/10.1021/jo00129a025
https://doi.org/10.1021/jo00129a025
Publikováno v:
Tetrahedron Letters. 35:397-400
The synthesis of three heterocycles 1–3 presenting identical faces containing a hydrogen bonding code for self-assembly is described. Pyrimidoquinazolinetetrone 1 and diaminopyrimidoquinazolinedione 2 were approached using a double Chapman rearrang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f189330331d45e9b5f1eac84286c547
https://doi.org/10.1016/0040-4039(94)85063-1
https://doi.org/10.1016/0040-4039(94)85063-1
Publikováno v:
Organic Letters. 4:3963-3965
[formula: see text] The stereoselective preparation of C-linked D-gluco- and D-galactopyranosyl L-serines in their alpha and beta forms is herein reported. The syntheses require the conversion of the allyl C-glycopyranosides into their iodoethyl deri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2b2e512421acbaff16816c9d5f1e3a8
https://doi.org/10.1021/ol026839w
https://doi.org/10.1021/ol026839w