Zobrazeno 1 - 10
of 141
pro vyhledávání: '"Ernest D. Laue"'
Autor:
Amogh Gopinathan Nair, Nick Rabas, Sara Lejon, Caleb Homiski, Michael J. Osborne, Normand Cyr, Aleksandr Sverzhinsky, Thomas Melendy, John M. Pascal, Ernest D. Laue, Katherine L. B. Borden, James G. Omichinski, Alain Verreault
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11099 (2022)
The eukaryotic DNA replication fork is a hub of enzymes that continuously act to synthesize DNA, propagate DNA methylation and other epigenetic marks, perform quality control, repair nascent DNA, and package this DNA into chromatin. Many of the enzym
Externí odkaz:
https://doaj.org/article/2e59bc152815426e9ca923121e0e3f23
Autor:
Meike Wiese, Andrew J. Bannister, Srinjan Basu, Wayne Boucher, Kai Wohlfahrt, Maria A. Christophorou, Michael L. Nielsen, David Klenerman, Ernest D. Laue, Tony Kouzarides
Publikováno v:
Epigenetics & Chromatin, Vol 12, Iss 1, Pp 1-17 (2019)
Abstract Background Stem cell differentiation involves major chromatin reorganisation, heterochromatin formation and genomic relocalisation of structural proteins, including heterochromatin protein 1 gamma (HP1γ). As the principal reader of the repr
Externí odkaz:
https://doaj.org/article/3abeefb38c8647619e3e0901093a5eca
Autor:
Srinjan Basu, Lisa-Maria Needham, David Lando, Edward J. R. Taylor, Kai J. Wohlfahrt, Devina Shah, Wayne Boucher, Yi Lei Tan, Lawrence E. Bates, Olga Tkachenko, Julie Cramard, B. Christoffer Lagerholm, Christian Eggeling, Brian Hendrich, Dave Klenerman, Steven F. Lee, Ernest D. Laue
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Single molecule tracking of fluorescent proteins in live cells is temporally limited by fluorophore photobleaching. Here the authors show using fluorophore pairs that FRET competes with photobleaching to improve photostability and allow longer-term t
Externí odkaz:
https://doaj.org/article/4ba0bd5ae2024d44b50386dc802df3dc
Autor:
Jonathan T. Siebert, Alexey N. Kivel, Liam P. Atkinson, Tim J. Stevens, Ernest D. Laue, Peter Virnau
Publikováno v:
Polymers, Vol 9, Iss 8, p 317 (2017)
Recent developments have for the first time allowed the determination of three-dimensional structures of individual chromosomes and genomes in nuclei of single haploid mouse embryonic stem (ES) cells based on Hi–C chromosome conformation contact da
Externí odkaz:
https://doaj.org/article/69737147d0b9471cbfa4a9400e02af98
Autor:
David Lando, Ulrike Endesfelder, Harald Berger, Lakxmi Subramanian, Paul D. Dunne, James McColl, David Klenerman, Antony M. Carr, Markus Sauer, Robin C. Allshire, Mike Heilemann, Ernest D. Laue
Publikováno v:
Open Biology, Vol 2, Iss 7 (2012)
The inheritance of the histone H3 variant CENP-A in nucleosomes at centromeres following DNA replication is mediated by an epigenetic mechanism. To understand the process of epigenetic inheritance, or propagation of histones and histone variants, as
Externí odkaz:
https://doaj.org/article/d4434d82101348dfb7371e24d1b3bdca
Autor:
Martin Leeb, Simon Hippenmeyer, Florian M. Pauler, Matthias Farlik, Perry Acf, Maki Asami, Ernest D. Laue, Toru Suzuki, Laura Santini, Florian Halbritter, Nick Warr, Xiaoyan Ma, Julia Ramesmayer, Andreas Beyer, Fabian Titz-Teixeira, Andreas Lackner, Christoph Bock
In mammals, chromatin marks at imprinted genes are asymmetrically inherited to control parentally-biased gene expression. This control is thought predominantly to involve parent-specific differentially methylated regions (DMR) in genomic DNA. However
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ba0d276fec465b078c5e9cd165a4673
https://doi.org/10.1101/2020.11.03.366948
https://doi.org/10.1101/2020.11.03.366948
Autor:
Srinjan Basu, Ofir Shukron, Dominic Hall, Pierre Parruto, Aleks Ponjavic, Devina Shah, Wayne Boucher, Dave Lando, Wei Zhang, Nicola Reynolds, Louisa H Sober, Aleksandra Jartseva, Ramy Ragheb, Xiaoyan Ma, Julie Cramard, Robin Floyd, Georgina Brown, Jenny Balmer, Thomas A Drury, Alex Carr, Lisa-Maria Needham, Alice Aubert, Guillaume Communie, Kavan Gor, Maike Steindel, Luis Morey, Enrique Blanco, Till Bartke, Luciano Di Croce, Imre Berger, Christiane Schaffitzel, Steven Lee, Tim J Stevens, David Klenerman, Brian Hendrich, David Holcman, Ernest D Laue
Enhancer-promoter dynamics are crucial for the spatiotemporal control of gene expression, but it remains unclear whether these dynamics are controlled by chromatin regulators, such as the nucleosome remodelling and deacetylase (NuRD) complex. The NuR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa613ef1322360f378afdacc6a1f673f
Publikováno v:
Nucleus
Single-cell chromosome conformation capture approaches are revealing the extent of cell-to-cell variability in the organization and packaging of genomes. These single-cell methods, unlike their multi-cell counterparts, allow straightforward computati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f38a48d78dc40fb587e2f7019d1281b6
Autor:
Andy Riddell, Tim J. Stevens, Dave Klenerman, Martin Leeb, Steven F. Lee, Brian Hendrich, Kai J. Wohlfahrt, Wayne Boucher, Srinjan Basu, Liam P Atkinson, Yang Cao, Ernest D. Laue, David Lando
Fluorescence imaging and chromosome conformation capture assays such as Hi-C are key tools for studying genome organization. However, traditionally, they have been carried out independently, making integration of the two types of data difficult to pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6a52f6d57103557e2a3142d068e0ad8
Autor:
Eaazhisai Kandiah, Juri Rappsilber, Aleksandra A. Watson, Eric Forest, Laszlo Tora, Christine Koehler, Carol V. Robinson, Anna L Chambers, Adam Round, Petr Man, Tiago Baptista, Arturo Temblador, Elisabeth Scheer, Imre Berger, Edward A. Lemke, Ima Obong-Ebong, Ernest D. Laue, Christoph Bieniossek, Kapil Gupta, Juan Zou, Didier Devys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::576dfe218cc9ed9ba417e72d4e40daef
https://doi.org/10.7554/elife.30395.028
https://doi.org/10.7554/elife.30395.028