Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Ernest Barbosa"'
Autor:
Ajaib Singh Paintlia, Anne Genevieve Gilg, Mushfiquddin Khan, Avtar Kaur Singh, Ernest Barbosa, Inderjit Singh
Publikováno v:
Neurobiology of Disease, Vol 14, Iss 3, Pp 425-439 (2003)
This study was designed to understand the role of inflammatory mediators involved in the neurobiology of childhood adrenoleukodystrophy (cALD) by comparing the differential expression of the inflammatory mediators with metabolite very long chain fatt
Externí odkaz:
https://doaj.org/article/83cbc5471adf4c9888d125a7de2f8765
Publikováno v:
Journal of Neurochemistry. 101:182-200
We have previously reported neuroprotection in spinal cord injury (SCI) by Lipitor [atorvastatin (AT)]-pre-treatment. Though informative, pre-treatment studies find only limited clinical application as trauma occurrence is unpredictable. Therefore, t
Publikováno v:
American Journal of Obstetrics and Gynecology. 193:952-956
Objective To determine whether N-acetylcysteine attenuates abnormal changes in the reduced uterine perfusion pressure model. Study design Twenty-four timed-pregnant Sprague-Dawley rats underwent sham surgery or the reduced uterine perfusion pressure
Publikováno v:
Journal of Neuroscience Research. 79:340-350
Spinal cord injury (SCI) is a devastating and complex clinical condition involving proinflammatory cytokines and nitric oxide toxicity that produces a predictable pattern of progressive injury entailing neuronal loss, axonal destruction, and demyelin
Autor:
Avtar K. Singh, Manjeet K. Paintlia, Anne G. Gilg, Ernest Barbosa, Romesh Stanislaus, Ajaib S. Paintlia, Inderjit Singh
Publikováno v:
Journal of Neuroscience Research. 77:63-81
The attenuation of experimental autoimmune encephalomyelitis (EAE) by Lovastatin (LOV) has now been well established. The present study was designed to explore the global effect of LOV treatment on expression of immune-related genes in lumbar spinal
Apparent genotype-phenotype correlation in childhood, adolescent, and adult Chediak-Higashi syndrome
Autor:
Mohammad A. Karim, Karen J. Moore, Eiichiro Uyama, Alex V. Levin, Outi Vierimaa, Friedmar Kreuz, Deborah L. Nagle, Ernest Barbosa, Kazuyoshi Fukai, Hiroaki Miyajima, José R. Regueiro, Carolyn Russo, Jangsuk Oh, Sirpa Kivrikko, Yasushi Ishida, Christoph Klein, Alexandra H. Filipovich, Koji Suzuki, Tzipora C. Falik-Borenstein, Richard A. Spritz
Publikováno v:
American Journal of Medical Genetics. 108:16-22
Chediak-Higashi syndrome (CHS) is a rare autosomal recessive disorder characterized by severe immunologic defects, reduced pigmentation, bleeding tendency, and progressive neurological dysfunction. Most patients present in early childhood and die unl
Autor:
Renée Betros, Jeffery R. Craver, Joel K. Curé, Mushfiquddin Khan, G. Shashidhar Pai, Ernest Barbosa, L. Lyndon Key, Inderjit Singh
Publikováno v:
Molecular Genetics and Metabolism. 69:312-322
X-linked adrenoleukodystrophy (X-ALD) is a progressive demyelinating disorder whose neurological signs and symptoms can manifest in childhood as cerebral ALD or in adulthood in the form of a progressive myelopathy (AMN). The consistent metabolic abno
Publikováno v:
Pediatric Neurology. 21:429-443
Perinatal asphyxia remains one of the most devastating neurologic processes. Although the understanding of the pathophysiology after perinatal asphyxia is extensive, there are few therapeutic interventions available to prevent or even mitigate the de
Autor:
J. Michael Murphy, Kenneth R. Holden, Deborah Anderson, David A. Griesemer, Eve G. Spratt, Michael S. Jellinek, Maria E. Pagano, Michelle M. Macias, Ernest Barbosa
Publikováno v:
Pediatric Neurology. 20:116-120
The purpose of this study was to evaluate the effectiveness of the Pediatric Symptom Checklist (PSC) as a mental health screening instrument in a busy pediatric neurology population in comparison with more lengthy, time-consuming assessment methods.
Autor:
Jean-Michel Goust, Naren L. Banik, Edward L. Hogan, Ernest Barbosa, Rajendra V. Deshpande, Arun K. Chakrabarti
Publikováno v:
Journal of Biological Chemistry. 270:2497-2505
Although calpain is ubiquitously present in human tissues and is thought to play a role in demyelination, its activity is very low in resting normal lymphocytes. To determine the nature of calpain expression at the mRNA and protein levels in human ly