Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Erna van Loghem"'
Autor:
Erna van Loghem, Jeike Biewenga
Publikováno v:
Vox Sanguinis. 36:193-198
A new gamma 3 heavy chain disease (gamma 3-HCD) protein (Emm) is described. A molecular weight of 70,000-80,000 daltons was estimated. Antigenic analysis showed that protein Emm lacks light chains and the CH1 domain of heavy chains, whereas the antig
Autor:
Erna van Loghem, A.M. Leeuwen, Gerda de Lange, L. E. Nijenhuis, Marie-Paule Lefranc, G. Lefranc, P.H. Eede
Publikováno v:
Vox Sanguinis. 43:301-309
Inheritance of an excess of immunoglobulin allotypes in one haplotype was encountered which could not be explained by the assumption of a duplicated locus. The surplus of allotypes was related to markers on the CH3 domain of gamma 3 chains. Two such
Autor:
Erna van Loghem
Publikováno v:
European Journal of Immunology. 4:57-60
Two families were investigated for the occurrence of IgA deficiency and antibodies to IgA. Several members of the families were found to be deficient for IgA1, as well as for IgA2, which strongly suggested that the disorder is genetically determined.
Autor:
Gerda de Lange, Erna van Loghem
Publikováno v:
Vox Sanguinis. 37:329-337
Non-human primate sera were investigated for the presence of various human immunoglobulin epitopes including allotypes of kappa-, gamma 1-, gamma 2-, gamma 3- and alpha 2-chains, isotypes of kappa-, gamma 1-, gamma 2-, gamma 3-, gamma 4-, alpha 1-, a
Autor:
J. Oliemans, Gerda de Lange, Peter van Eede, F. Daus, Fred van Leeuwen, Erna van Loghem, Jeike Biewenga
Publikováno v:
Vox Sanguinis. 45:426-431
The distribution of antigenic determinants on human IgA was studied with fragments and mutants of IgA1. F(abc)2 and Fabc, lacking the CH3 domain, F(ab')2 and Fab', lacking the CH2 and CH3 domain, Fab that further lacks most of the hinge region, and F
Autor:
Claude Ropartz, Gerda de Lange, Jean-Louis Serre, Jean-Marc Lalouel, Gérard Lefranc, Gilles Pison, Erna van Loghem, Jacques Loiselet, Liliane Rivat
Publikováno v:
Human Genetics. 41:197-209
Allotypes of IgG1, IgG2, IgG3, and IgA2 subclasses were investigated in seven Lebanese communities (three Moslem and four Christian). The Gm-Am haplotypes found were mainly those prevalent in Caucasians with a low frequency of haplotypes usually obse
Autor:
Martijn H. Breuning, Erna van Loghem, P. Meera Khan, J. B. Bijlsma, Ella M. van den Berg-Loonen, Lourens E. Nijenhuis, Luigi F. Bernini
Publikováno v:
Human Genetics. 37:131-139
A detailed marker gene study in a large Dutch kindred segregating for a reciprocal translocation between the chromosomes 6 and 20, t(6;20) (p21; p13), revealed a close linkage between the HLA genes and the breakpoint on the short arm of 6. During thi
Autor:
Jeike Biewenga, Erna van Loghem
Publikováno v:
Molecular Immunology. 20:1001-1007
The location of isotypic, isoallotypic and allotypic determinants is reviewed in the light of data obtained when specific antisera are tested with proteolytic fragments of IgA molecules or mutants of IgA obtained from patients with alpha-heavy chain
Publikováno v:
Vox Sanguinis. 37:262-267
Immunization of a chimpanzee, a gibbon, a baboon and a rhesus monkey with human globulins gave different results. While chimpanzees did not produce any anti-human antibodies, baboon and rhesus monkey responded by producing anti-human IgG antibodies t
Autor:
Ludmila P. Osipova, B. J. M. Zegers, Gerda de Lange and, R. I. Sukernik, H. Matsumoto, G. Lefrance, Erna van Loghem
Publikováno v:
European Journal of Immunogenetics. 7:285-299
Individuals with selective absence of IgG1 and IgG2 were discovered by testing for allotypes and isotypes of the respective sub-classes. These individuals were homozygous for sub-class deleted Gm-Am haplotypes, as shown by allotype studies in two fam