Declining free thyroxine levels over time in irradiated childhood brain tumor survivors

Autor: Laura van Iersel, Sarah C Clement, Antoinette Y N Schouten-van Meeteren, Annemieke M Boot, Hedi L Claahsen-van der Grinten, Bernd Granzen, K Sen Han, Geert O Janssens, Erna M Michiels, A S Paul van Trotsenburg, W Peter Vandertop, Dannis G van Vuurden, Hubert N Caron, Leontien C M Kremer, Hanneke M van Santen

Publikováno v: Endocrine Connections, Vol 7, Iss 12, Pp 1322-1332 (2018)

Objective: The incidence of cranial radiotherapy (cRT)–induced central hypothyroidism (TSHD) in childhood brain tumor survivors (CBTS) is reported to be low. However, TSHD may be more frequent than currently suspected, as its diagnosis is challengi

Externí odkaz: https://doaj.org/article/8825babda5f54e53877be02d010dc0f9

Prevalence and Risk Factors of Early Endocrine Disorders in Childhood Brain Tumor Survivors: A Nationwide, Multicenter Study.

Autor: Clement SC; Sarah C. Clement, K. Sen Han, and Hanneke M. van Santen, University Medical Center Utrecht, Utrecht; Sarah C. Clement, Antoinette Y.N. Schouten-van Meeteren, A.S. Paul van Trotsenburg, W. Peter Vandertop, Leontien C.M. Kremer, and Hubert N. Caron, Academic Medical Center, University of Amsterdam; W. Peter Vandertop and Dannis G. van Vuurden, Vrije Universiteit University Medical Center, Amsterdam; Annemieke M. Boot, University Medical Center Groningen, University of Groningen, Groningen; Hedy L. Claahsen-van der Grinten and Geert O. Janssens, Radboud University Nijmegen Medical Center, Nijmegen; Bernd Granzen, Maastricht University Medical Center, Maastricht; and Erna M. Michiels, Erasmus Medical Center-Sophia Children's Hospital, Rotterdam, the Netherlands., Schouten-van Meeteren AY; Sarah C. Clement, K. Sen Han, and Hanneke M. van Santen, University Medical Center Utrecht, Utrecht; Sarah C. Clement, Antoinette Y.N. Schouten-van Meeteren, A.S. Paul van Trotsenburg, W. Peter Vandertop, Leontien C.M. Kremer, and Hubert N. Caron, Academic Medical Center, University of Amsterdam; W. Peter Vandertop and Dannis G. van Vuurden, Vrije Universiteit University Medical Center, Amsterdam; Annemieke M. Boot, University Medical Center Groningen, University of Groningen, Groningen; Hedy L. Claahsen-van der Grinten and Geert O. Janssens, Radboud University Nijmegen Medical Center, Nijmegen; Bernd Granzen, Maastricht University Medical Center, Maastricht; and Erna M. Michiels, Erasmus Medical Center-Sophia Children's Hospital, Rotterdam, the Netherlands., Boot AM; Sarah C. Clement, K. Sen Han, and Hanneke M. van Santen, University Medical Center Utrecht, Utrecht; Sarah C. Clement, Antoinette Y.N. Schouten-van Meeteren, A.S. Paul van Trotsenburg, W. Peter Vandertop, Leontien C.M. Kremer, and Hubert N. Caron, Academic Medical Center, University of Amsterdam; W. Peter Vandertop and Dannis G. van Vuurden, Vrije Universiteit University Medical Center, Amsterdam; Annemieke M. Boot, University Medical Center Groningen, University of Groningen, Groningen; Hedy L. Claahsen-van der Grinten and Geert O. Janssens, Radboud University Nijmegen Medical Center, Nijmegen; Bernd Granzen, Maastricht University Medical Center, Maastricht; and Erna M. Michiels, Erasmus Medical Center-Sophia Children's Hospital, Rotterdam, the Netherlands., Claahsen-van der Grinten HL; Sarah C. Clement, K. Sen Han, and Hanneke M. van Santen, University Medical Center Utrecht, Utrecht; Sarah C. Clement, Antoinette Y.N. Schouten-van Meeteren, A.S. Paul van Trotsenburg, W. Peter Vandertop, Leontien C.M. Kremer, and Hubert N. Caron, Academic Medical Center, University of Amsterdam; W. Peter Vandertop and Dannis G. van Vuurden, Vrije Universiteit University Medical Center, Amsterdam; Annemieke M. Boot, University Medical Center Groningen, University of Groningen, Groningen; Hedy L. Claahsen-van der Grinten and Geert O. Janssens, Radboud University Nijmegen Medical Center, Nijmegen; Bernd Granzen, Maastricht University Medical Center, Maastricht; and Erna M. Michiels, Erasmus Medical Center-Sophia Children's Hospital, Rotterdam, the Netherlands., Granzen B; Sarah C. Clement, K. Sen Han, and Hanneke M. van Santen, University Medical Center Utrecht, Utrecht; Sarah C. Clement, Antoinette Y.N. Schouten-van Meeteren, A.S. Paul van Trotsenburg, W. Peter Vandertop, Leontien C.M. Kremer, and Hubert N. Caron, Academic Medical Center, University of Amsterdam; W. Peter Vandertop and Dannis G. van Vuurden, Vrije Universiteit University Medical Center, Amsterdam; Annemieke M. Boot, University Medical Center Groningen, University of Groningen, Groningen; Hedy L. Claahsen-van der Grinten and Geert O. Janssens, Radboud University Nijmegen Medical Center, Nijmegen; Bernd Granzen, Maastricht University Medical Center, Maastricht; and Erna M. Michiels, Erasmus Medical Center-Sophia Children's Hospital, Rotterdam, the Netherlands., Sen Han K; Sarah C. Clement, K. Sen Han, and Hanneke M. van Santen, University Medical Center Utrecht, Utrecht; Sarah C. Clement, Antoinette Y.N. Schouten-van Meeteren, A.S. Paul van Trotsenburg, W. Peter Vandertop, Leontien C.M. Kremer, and Hubert N. Caron, Academic Medical Center, University of Amsterdam; W. Peter Vandertop and Dannis G. van Vuurden, Vrije Universiteit University Medical Center, Amsterdam; Annemieke M. Boot, University Medical Center Groningen, University of Groningen, Groningen; Hedy L. Claahsen-van der Grinten and Geert O. Janssens, Radboud University Nijmegen Medical Center, Nijmegen; Bernd Granzen, Maastricht University Medical Center, Maastricht; and Erna M. Michiels, Erasmus Medical Center-Sophia Children's Hospital, Rotterdam, the Netherlands., Janssens GO; Sarah C. Clement, K. Sen Han, and Hanneke M. van Santen, University Medical Center Utrecht, Utrecht; Sarah C. Clement, Antoinette Y.N. Schouten-van Meeteren, A.S. Paul van Trotsenburg, W. Peter Vandertop, Leontien C.M. Kremer, and Hubert N. Caron, Academic Medical Center, University of Amsterdam; W. Peter Vandertop and Dannis G. van Vuurden, Vrije Universiteit University Medical Center, Amsterdam; Annemieke M. Boot, University Medical Center Groningen, University of Groningen, Groningen; Hedy L. Claahsen-van der Grinten and Geert O. Janssens, Radboud University Nijmegen Medical Center, Nijmegen; Bernd Granzen, Maastricht University Medical Center, Maastricht; and Erna M. Michiels, Erasmus Medical Center-Sophia Children's Hospital, Rotterdam, the Netherlands., Michiels EM; Sarah C. Clement, K. Sen Han, and Hanneke M. van Santen, University Medical Center Utrecht, Utrecht; Sarah C. Clement, Antoinette Y.N. Schouten-van Meeteren, A.S. Paul van Trotsenburg, W. Peter Vandertop, Leontien C.M. Kremer, and Hubert N. Caron, Academic Medical Center, University of Amsterdam; W. Peter Vandertop and Dannis G. van Vuurden, Vrije Universiteit University Medical Center, Amsterdam; Annemieke M. Boot, University Medical Center Groningen, University of Groningen, Groningen; Hedy L. Claahsen-van der Grinten and Geert O. Janssens, Radboud University Nijmegen Medical Center, Nijmegen; Bernd Granzen, Maastricht University Medical Center, Maastricht; and Erna M. Michiels, Erasmus Medical Center-Sophia Children's Hospital, Rotterdam, the Netherlands., van Trotsenburg AS; Sarah C. Clement, K. Sen Han, and Hanneke M. van Santen, University Medical Center Utrecht, Utrecht; Sarah C. Clement, Antoinette Y.N. Schouten-van Meeteren, A.S. Paul van Trotsenburg, W. Peter Vandertop, Leontien C.M. Kremer, and Hubert N. Caron, Academic Medical Center, University of Amsterdam; W. Peter Vandertop and Dannis G. van Vuurden, Vrije Universiteit University Medical Center, Amsterdam; Annemieke M. Boot, University Medical Center Groningen, University of Groningen, Groningen; Hedy L. Claahsen-van der Grinten and Geert O. Janssens, Radboud University Nijmegen Medical Center, Nijmegen; Bernd Granzen, Maastricht University Medical Center, Maastricht; and Erna M. Michiels, Erasmus Medical Center-Sophia Children's Hospital, Rotterdam, the Netherlands., Vandertop WP; Sarah C. Clement, K. Sen Han, and Hanneke M. van Santen, University Medical Center Utrecht, Utrecht; Sarah C. Clement, Antoinette Y.N. Schouten-van Meeteren, A.S. Paul van Trotsenburg, W. Peter Vandertop, Leontien C.M. Kremer, and Hubert N. Caron, Academic Medical Center, University of Amsterdam; W. Peter Vandertop and Dannis G. van Vuurden, Vrije Universiteit University Medical Center, Amsterdam; Annemieke M. Boot, University Medical Center Groningen, University of Groningen, Groningen; Hedy L. Claahsen-van der Grinten and Geert O. Janssens, Radboud University Nijmegen Medical Center, Nijmegen; Bernd Granzen, Maastricht University Medical Center, Maastricht; and Erna M. Michiels, Erasmus Medical Center-Sophia Children's Hospital, Rotterdam, the Netherlands., van Vuurden DG; Sarah C. Clement, K. Sen Han, and Hanneke M. van Santen, University Medical Center Utrecht, Utrecht; Sarah C. Clement, Antoinette Y.N. Schouten-van Meeteren, A.S. Paul van Trotsenburg, W. Peter Vandertop, Leontien C.M. Kremer, and Hubert N. Caron, Academic Medical Center, University of Amsterdam; W. Peter Vandertop and Dannis G. van Vuurden, Vrije Universiteit University Medical Center, Amsterdam; Annemieke M. Boot, University Medical Center Groningen, University of Groningen, Groningen; Hedy L. Claahsen-van der Grinten and Geert O. Janssens, Radboud University Nijmegen Medical Center, Nijmegen; Bernd Granzen, Maastricht University Medical Center, Maastricht; and Erna M. Michiels, Erasmus Medical Center-Sophia Children's Hospital, Rotterdam, the Netherlands., Kremer LC; Sarah C. Clement, K. Sen Han, and Hanneke M. van Santen, University Medical Center Utrecht, Utrecht; Sarah C. Clement, Antoinette Y.N. Schouten-van Meeteren, A.S. Paul van Trotsenburg, W. Peter Vandertop, Leontien C.M. Kremer, and Hubert N. Caron, Academic Medical Center, University of Amsterdam; W. Peter Vandertop and Dannis G. van Vuurden, Vrije Universiteit University Medical Center, Amsterdam; Annemieke M. Boot, University Medical Center Groningen, University of Groningen, Groningen; Hedy L. Claahsen-van der Grinten and Geert O. Janssens, Radboud University Nijmegen Medical Center, Nijmegen; Bernd Granzen, Maastricht University Medical Center, Maastricht; and Erna M. Michiels, Erasmus Medical Center-Sophia Children's Hospital, Rotterdam, the Netherlands., Caron HN; Sarah C. Clement, K. Sen Han, and Hanneke M. van Santen, University Medical Center Utrecht, Utrecht; Sarah C. Clement, Antoinette Y.N. Schouten-van Meeteren, A.S. Paul van Trotsenburg, W. Peter Vandertop, Leontien C.M. Kremer, and Hubert N. Caron, Academic Medical Center, University of Amsterdam; W. Peter Vandertop and Dannis G. van Vuurden, Vrije Universiteit University Medical Center, Amsterdam; Annemieke M. Boot, University Medical Center Groningen, University of Groningen, Groningen; Hedy L. Claahsen-van der Grinten and Geert O. Janssens, Radboud University Nijmegen Medical Center, Nijmegen; Bernd Granzen, Maastricht University Medical Center, Maastricht; and Erna M. Michiels, Erasmus Medical Center-Sophia Children's Hospital, Rotterdam, the Netherlands., van Santen HM; Sarah C. Clement, K. Sen Han, and Hanneke M. van Santen, University Medical Center Utrecht, Utrecht; Sarah C. Clement, Antoinette Y.N. Schouten-van Meeteren, A.S. Paul van Trotsenburg, W. Peter Vandertop, Leontien C.M. Kremer, and Hubert N. Caron, Academic Medical Center, University of Amsterdam; W. Peter Vandertop and Dannis G. van Vuurden, Vrije Universiteit University Medical Center, Amsterdam; Annemieke M. Boot, University Medical Center Groningen, University of Groningen, Groningen; Hedy L. Claahsen-van der Grinten and Geert O. Janssens, Radboud University Nijmegen Medical Center, Nijmegen; Bernd Granzen, Maastricht University Medical Center, Maastricht; and Erna M. Michiels, Erasmus Medical Center-Sophia Children's Hospital, Rotterdam, the Netherlands.

Publikováno v: Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2016 Dec 20; Vol. 34 (36), pp. 4362-4370. Date of Electronic Publication: 2016 Oct 31.