Výsledky vyhledávání - "Erna, Motsch"

Lung function impairment in the German Lung Cancer Screening Intervention Study (LUSI): prevalence, symptoms, and associations with lung cancer risk, tumor histology and all-cause mortality

Autor: Rudolf, Kaaks, Evangelia, Christodoulou, Erna, Motsch, Verena, Katzke, Mark O, Wielpütz, Hans-Ulrich, Kauczor, Claus Peter, Heussel, Monika, Eichinger, Stefan, Delorme

Publikováno v: Translational Lung Cancer Research. 11:1896-1911

Lung cancer screening may provide a favorable opportunity for a spirometry examination, to diagnose participants with undiagnosed lung function impairments, or to improve targeting of computed tomography (CT) screening intensity in view of expected n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea71f95bf0362cc048ef8d3e97674255
https://doi.org/10.21037/tlcr-22-63

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Can autoantibody tests enhance lung cancer screening?—an evaluation of EarlyCDT®-Lung in context of the German Lung Cancer Screening Intervention Trial (LUSI)

Autor: Erna Motsch, Sandra González Maldonado, Rudolf Kaaks, Stefan Delorme, Theron Johnson

Publikováno v: Translational Lung Cancer Research. 10:233-242

Background Tumor-associated autoantibodies are considered promising markers for early lung cancer detection; so far, however, their capacity to detect cancer has been tested mostly in a clinical context, but not in population screening settings. This

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2383819cdf8d6dd9e5819cb7e067a76f
https://doi.org/10.21037/tlcr-20-727

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Overdiagnosis in lung cancer screening: Estimates from the German Lung Cancer Screening Intervention Trial

Autor: Stefan Delorme, Erna Motsch, Sandra González Maldonado, Sylke Ruth Zeissig, Rudolf Kaaks, Claus Peter Heussel, Silke Hermann, Hans-Ulrich Kauczor, Anke Trotter

Publikováno v: International Journal of Cancer. 148:1097-1105

Overdiagnosis is a major potential harm of lung cancer screening; knowing its potential magnitude helps to optimize screening eligibility criteria. The German Lung Screening Intervention Trial ("LUSI") is a randomized trial among 4052 long-term smoke

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a168563684afafea7194a78f774b5aaa
https://doi.org/10.1002/ijc.33295

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Validation of multivariable lung cancer risk prediction models for the personalized assignment of optimal screening frequency: a retrospective analysis of data from the German Lung Cancer Screening Intervention Trial (LUSI)

Autor: Stefan Delorme, Rudolf Kaaks, Hans-Ulrich Kauczor, Sandra González Maldonado, Lucas Cory Hynes, Erna Motsch, Hilary A. Robbins, Claus Peter Heussel

Publikováno v: Transl Lung Cancer Res

Background Current guidelines for lung cancer screening via low-dose computed tomography recommend annual screening for all candidates meeting basic eligibility criteria. However, lung cancer risk of eligible screening participants can vary widely, a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b6a3de14eb242f8d03b3cc29aa620d7
https://europepmc.org/articles/PMC8044498/

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Can autoantibody tests enhance lung cancer screening?-an evaluation of EarlyCDT

Autor: Sandra, González Maldonado, Theron, Johnson, Erna, Motsch, Stefan, Delorme, Rudolf, Kaaks

Publikováno v: Transl Lung Cancer Res

BACKGROUND: Tumor-associated autoantibodies are considered promising markers for early lung cancer detection; so far, however, their capacity to detect cancer has been tested mostly in a clinical context, but not in population screening settings. Thi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::46be62fa680429ba690f6322d887e01d
https://pubmed.ncbi.nlm.nih.gov/33569307

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Evaluation of Prediction Models for Identifying Malignancy in Pulmonary Nodules Detected via Low-Dose Computed Tomography

Autor: Anika Hüsing, Erna Motsch, Sandra González Maldonado, Rudolf Kaaks, Stefan Delorme, Claus-Peter Heussel, Hans-Ulrich Kauczor

Publikováno v: JAMA network open. 3(2)

Malignancy prediction models based on participant-related characteristics and imaging parameters from low-dose computed tomography (CT) may improve decision-making regarding nodule management and diagnosis in lung cancer screening.To externally valid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3308bf3b00c1754be3830c255232c89c
https://pubmed.ncbi.nlm.nih.gov/32058548

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Lung cancer mortality reduction by LDCT screening-Results from the randomized German LUSI trial

Autor: Sandra González Maldonado, Erna Motsch, Stefan Delorme, Rudolf Kaaks, Philipp A. Schnabel, Hans-Ulrich Kauczor, Anthony B. Miller, Anke Trotter, Claus P. Heussel, Nikolaus Becker, Hendrik Dienemann

Publikováno v: International journal of cancerReferences. 146(6)

In 2011, the U.S. National Lung Cancer Screening Trial (NLST) reported a 20% reduction of lung cancer mortality after regular screening by low-dose computed tomography (LDCT), as compared to X-ray screening. The introduction of lung cancer screening

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62251a38d8352005eb3c8623916874d7
https://pubmed.ncbi.nlm.nih.gov/31162856

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Longitudinal airway remodeling in active and past smokers in a lung cancer screening population

Autor: Jan Tremper, Torben Buschulte, Erna Motsch, Mila Trauth, Monika Eichinger, Stefan Delorme, Bertram Jobst, Anke Trotter, Hans-Ulrich Kauczor, Marie-Luise Groß, Nikolaus Becker, Oliver Weinheimer, Mark O. Wielpütz

Publikováno v: European radiology. 29(6)

To longitudinally investigate smoking cessation-related changes of quantitative computed tomography (QCT)–based airway metrics in a group of heavy smokers. CT scans were acquired in a lung cancer screening population over 4 years at 12-month interv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::930365c8efd963d2b0ce048dadcd7f6d
https://pubmed.ncbi.nlm.nih.gov/30552475

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Randomized Study on Early Detection of Lung Cancer with MSCT in Germany: Results of the First 3 Years of Follow-up After Randomization

Autor: M.-L. Gross, Philipp A. Schnabel, Hans U. Kauczor, D.-E. Optazaite, A. Eigentopf, Claus P. Heussel, H. Dienemann, Michael Puderbach, Natalia Becker, Jan Tremper, Stefan Delorme, Monika Eichinger, Erna Motsch, Mark O. Wielpütz

Publikováno v: Journal of Thoracic Oncology. 10(6):890-896

Introduction The German Lung Cancer Screening Intervention Trial (LUSI) is one of the European randomized trials investigating the efficacy of low-dose multislice computed tomography (MSCT) as a screening tool for lung cancer. In the evaluation of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66e4ecc1439ebb5017fb6e1e9d90d182

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Effect of smoking cessation on quantitative computed tomography in smokers at risk in a lung cancer screening population

Autor: Oliver Weinheimer, Bertram J. Jobst, Marie-Luise Groß, Mark O. Wielpütz, Mila Trauth, Jan Tremper, Anke Eigentopf, Nikolaus Becker, Stefan Delorme, Hans-Ulrich Kauczor, Monika Eichinger, Erna Motsch

Publikováno v: European radiology. 28(2)

To longitudinally evaluate effects of smoking cessation on quantitative CT in a lung cancer screening cohort of heavy smokers over 4 years. After 4 years, low-dose chest CT was available for 314 long-term ex-smokers (ES), 404 continuous smokers (CS)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::317481f13a8e3882151e5bf7721820e1
https://pubmed.ncbi.nlm.nih.gov/28884215

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