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Akademický článek

The Medicago truncatula IEF Gene Is Crucial for the Progression of Bacterial Infection During Symbiosis

Autor: Szilárd Kovács, Ernő Kiss, Sándor Jenei, Erzsébet Fehér-Juhász, Attila Kereszt, Gabriella Endre

Publikováno v: Molecular Plant-Microbe Interactions, Vol 35, Iss 5, Pp 401-415 (2022)

Legumes are able to meet their nitrogen need by establishing nitrogen-fixing symbiosis with rhizobia. Nitrogen fixation is performed by rhizobia, which has been converted to bacteroids, in newly formed organs, the root nodules. In the model legume Me

Externí odkaz: https://doaj.org/article/5e1ad1a5ba4c47c5805c0e6e141ec49e

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Akademický článek

A series of xanthenes inhibiting Rad6 function and Rad6-Rad18 interaction in the PCNA ubiquitination cascade

Autor: Gabriel Fenteany, Gaurav Sharma, Paras Gaur, Attila Borics, Edit Wéber, Ernő Kiss, Lajos Haracska

Publikováno v: iScience, Vol 25, Iss 4, Pp 104053- (2022)

Summary: Ubiquitination of proliferating cell nuclear antigen (PCNA) triggers pathways of DNA damage tolerance, including mutagenic translesion DNA synthesis, and comprises a cascade of reactions involving the E1 ubiquitin-activating enzyme Uba1, the

Externí odkaz: https://doaj.org/article/b4abc35bfc74403c82c1a411e01815c4

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Akademický článek

Robust high-throughput assays to assess discrete steps in ubiquitination and related cascades

Autor: Gabriel Fenteany, Paras Gaur, Gaurav Sharma, Lajos Pintér, Ernő Kiss, Lajos Haracska

Publikováno v: BMC Molecular and Cell Biology, Vol 21, Iss 1, Pp 1-16 (2020)

Abstract Background Ubiquitination and ubiquitin-like protein post-translational modifications play an enormous number of roles in cellular processes. These modifications are constituted of multistep reaction cascades. Readily implementable and robus

Externí odkaz: https://doaj.org/article/73aebcb242d04449b6eda0ee75c35490

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A Comprehensive Evaluation of the Performance of Prediction Algorithms on Clinically Relevant Missense Variants

Autor: Erda Qorri, Bertalan Takács, Alexandra Gráf, Márton Zsolt Enyedi, Lajos Pintér, Ernő Kiss, Lajos Haracska

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 23; Issue 14; Pages: 7946

The rapid integration of genomic technologies in clinical diagnostics has resulted in the detection of a multitude of missense variants whose clinical significance is often unknown. As a result, a plethora of computational tools have been developed t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb4652bd5486fd128b49b87c0b44b614
https://pubmed.ncbi.nlm.nih.gov/35887294

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The

Autor: Szilárd, Kovács, Ernő, Kiss, Sándor, Jenei, Erzsébet, Fehér-Juhász, Attila, Kereszt, Gabriella, Endre

Publikováno v: Molecular plant-microbe interactions : MPMI. 35(5)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d5c3ecbc2f3f155c37d2eb6b24f812e6
https://pubmed.ncbi.nlm.nih.gov/35171648

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Akademický článek

The rkp-3 Gene Region of Sinorhizobium meliloti Rm41 Contains Strain-Specific Genes that Determine K Antigen Structure

Autor: Ernő Kiss, Attila Kereszt, Fatime Barta, Samuel Stephens, Bradley L. Reuhs, Ádám Kondorosi, Péter Putnoky

Publikováno v: Molecular Plant-Microbe Interactions, Vol 14, Iss 12, Pp 1395-1403 (2001)

The rkp-3 region is indispensable for capsular polysaccharide (K antigen) synthesis in Sinorhizobium meliloti Rm41. Strain Rm41 produces a K antigen of strain-specific structure, designated as the KR5 antigen. The data in this report show that the rk

Externí odkaz: https://doaj.org/article/784a71a1130249808756374ffc68e07d

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The Combination of Single-Cell and Next-Generation Sequencing Can Reveal Mosaicism for BRCA2 Mutations and the Fine Molecular Details of Tumorigenesis

Autor: Arpad Balind, Gábor Jaksa, Ernő Kiss, Peter Horvath, Márton Zsolt Enyedi, Éva Kriston-Pál, Lajos Haracska, Lajos Pintér, Éva Ezer, Farkas Sükösd, Alexandra Gráf

Publikováno v: Cancers
Volume 13
Issue 10
Cancers, Vol 13, Iss 2354, p 2354 (2021)

Germline mutations in the BRCA1 and BRCA2 genes are responsible for hereditary breast and ovarian cancer syndrome. Germline and somatic BRCA1/2 mutations may define therapeutic targets and refine cancer treatment options. However, routine BRCA diagno

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcdfeaea709fdda37e2b42bc73581a7c
http://hdl.handle.net/10138/331901

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Robust high-throughput assays to assess discrete steps in ubiquitination and related cascades

Autor: Lajos Haracska, Lajos Pintér, Gaurav Sharma, Gabriel Fenteany, Ernő Kiss, Paras Gaur

Publikováno v: BMC Molecular and Cell Biology, Vol 21, Iss 1, Pp 1-16 (2020)
BMC Molecular and Cell Biology

Background Ubiquitination and ubiquitin-like protein post-translational modifications play an enormous number of roles in cellular processes. These modifications are constituted of multistep reaction cascades. Readily implementable and robust methods

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b55f6ec8a17e4c9d53090e1305b2940d
https://doi.org/10.1186/s12860-020-00262-5

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Multilevel structure–activity profiling reveals multiple green tea compound families that each modulate ubiquitin-activating enzyme and ubiquitination by a distinct mechanism

Autor: Paras Gaur, Gabriel Fenteany, László G. Puskás, Lili Hegedűs, Edit Wéber, Ernő Kiss, Tamás A. Martinek, Lajos Haracska, László Hackler, Kata Dudás

Publikováno v: Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-16 (2019)

We developed and implemented a reconstituted system to screen for modulators of the ubiquitination of proliferating cell nuclear antigen, a process that activates pathways of DNA damage tolerance and drug resistance. We identified the primary putativ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76b7bae5998ebd76d220b5330693ebaf
https://doi.org/10.1038/s41598-019-48888-6

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NAD1 Controls Defense-Like Responses in Medicago truncatula Symbiotic Nitrogen Fixing Nodules Following Rhizobial Colonization in a BacA-Independent Manner

Autor: Beatrix Horvath, Attila Farkas, Ferhan Ayaydin, Károly Bóka, Ágota Domonkos, Anikó Gombár, Gabriella Endre, Mónika T. Tóth, Lili Fodor, Péter Kaló, Attila Kereszt, Gyöngyi Z. Kováts, Ernő Kiss, Pascal Ratet, Szilárd Kovács

Publikováno v: Genes, Vol 8, Iss 12, p 387 (2017)
Genes; Volume 8; Issue 12; Pages: 387
Genes
Genes, MDPI, 2017, 8 (12), pp.387. ⟨10.3390/genes8120387⟩
Genes 12 (8), 1-21. (2017)

International audience; Legumes form endosymbiotic interaction with host compatible rhizobia, resulting in the development of nitrogen-fixing root nodules. Within symbiotic nodules, rhizobia are intracellularly accommodated in plant-derived membrane

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67a8eeb0157816f97c87acd4c4be1ef7
https://www.mdpi.com/2073-4425/8/12/387

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