A series of xanthenes inhibiting Rad6 function and Rad6-Rad18 interaction in the PCNA ubiquitination cascade

Autor: Gabriel Fenteany, Gaurav Sharma, Paras Gaur, Attila Borics, Edit Wéber, Ernő Kiss, Lajos Haracska

Publikováno v: iScience, Vol 25, Iss 4, Pp 104053- (2022)

Summary: Ubiquitination of proliferating cell nuclear antigen (PCNA) triggers pathways of DNA damage tolerance, including mutagenic translesion DNA synthesis, and comprises a cascade of reactions involving the E1 ubiquitin-activating enzyme Uba1, the

Externí odkaz: https://doaj.org/article/b4abc35bfc74403c82c1a411e01815c4

A Comprehensive Evaluation of the Performance of Prediction Algorithms on Clinically Relevant Missense Variants

Autor: Erda Qorri, Bertalan Takács, Alexandra Gráf, Márton Zsolt Enyedi, Lajos Pintér, Ernő Kiss, Lajos Haracska

Publikováno v: International Journal of Molecular Sciences, Vol 23, Iss 14, p 7946 (2022)

The rapid integration of genomic technologies in clinical diagnostics has resulted in the detection of a multitude of missense variants whose clinical significance is often unknown. As a result, a plethora of computational tools have been developed t

Externí odkaz: https://doaj.org/article/043f0a90726a48b093ae5dc4abb46c44

The rkp-3 Gene Region of Sinorhizobium meliloti Rm41 Contains Strain-Specific Genes that Determine K Antigen Structure

Autor: Ernő Kiss, Attila Kereszt, Fatime Barta, Samuel Stephens, Bradley L. Reuhs, Ádám Kondorosi, Péter Putnoky

Publikováno v: Molecular Plant-Microbe Interactions, Vol 14, Iss 12, Pp 1395-1403 (2001)

The rkp-3 region is indispensable for capsular polysaccharide (K antigen) synthesis in Sinorhizobium meliloti Rm41. Strain Rm41 produces a K antigen of strain-specific structure, designated as the KR5 antigen. The data in this report show that the rk

Externí odkaz: https://doaj.org/article/784a71a1130249808756374ffc68e07d

Robust high-throughput assays to assess discrete steps in ubiquitination and related cascades

Autor: Lajos Haracska, Lajos Pintér, Gaurav Sharma, Gabriel Fenteany, Ernő Kiss, Paras Gaur

Publikováno v: BMC Molecular and Cell Biology, Vol 21, Iss 1, Pp 1-16 (2020)
BMC Molecular and Cell Biology

Background Ubiquitination and ubiquitin-like protein post-translational modifications play an enormous number of roles in cellular processes. These modifications are constituted of multistep reaction cascades. Readily implementable and robust methods

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b55f6ec8a17e4c9d53090e1305b2940d
https://doi.org/10.1186/s12860-020-00262-5

NAD1 Controls Defense-Like Responses in Medicago truncatula Symbiotic Nitrogen Fixing Nodules Following Rhizobial Colonization in a BacA-Independent Manner

Autor: Beatrix Horvath, Attila Farkas, Ferhan Ayaydin, Károly Bóka, Ágota Domonkos, Anikó Gombár, Gabriella Endre, Mónika T. Tóth, Lili Fodor, Péter Kaló, Attila Kereszt, Gyöngyi Z. Kováts, Ernő Kiss, Pascal Ratet, Szilárd Kovács

Publikováno v: Genes, Vol 8, Iss 12, p 387 (2017)
Genes; Volume 8; Issue 12; Pages: 387
Genes
Genes, MDPI, 2017, 8 (12), pp.387. ⟨10.3390/genes8120387⟩
Genes 12 (8), 1-21. (2017)

International audience; Legumes form endosymbiotic interaction with host compatible rhizobia, resulting in the development of nitrogen-fixing root nodules. Within symbiotic nodules, rhizobia are intracellularly accommodated in plant-derived membrane

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67a8eeb0157816f97c87acd4c4be1ef7
https://www.mdpi.com/2073-4425/8/12/387