Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ermira Shuteriqi"'
Autor:
Jolanda van Leeuwen, Carles Pons, Guihong Tan, Jason Zi Wang, Jing Hou, Jochen Weile, Marinella Gebbia, Wendy Liang, Ermira Shuteriqi, Zhijian Li, Maykel Lopes, Matej Ušaj, Andreia Dos Santos Lopes, Natascha van Lieshout, Chad L Myers, Frederick P Roth, Patrick Aloy, Brenda J Andrews, Charles Boone
Publikováno v:
Molecular Systems Biology, Vol 16, Iss 9, Pp 1-24 (2020)
Abstract Essential genes tend to be highly conserved across eukaryotes, but, in some cases, their critical roles can be bypassed through genetic rewiring. From a systematic analysis of 728 different essential yeast genes, we discovered that 124 (17%)
Externí odkaz:
https://doaj.org/article/27e5a5f4f3414f1c97c8f31d1a196803
Autor:
Mojca Mattiazzi Usaj, Nil Sahin, Helena Friesen, Carles Pons, Matej Usaj, Myra Paz D Masinas, Ermira Shuteriqi, Aleksei Shkurin, Patrick Aloy, Quaid Morris, Charles Boone, Brenda J Andrews
Publikováno v:
Molecular Systems Biology, Vol 16, Iss 2, Pp 1-27 (2020)
Abstract Our ability to understand the genotype‐to‐phenotype relationship is hindered by the lack of detailed understanding of phenotypes at a single‐cell level. To systematically assess cell‐to‐cell phenotypic variability, we combined auto
Externí odkaz:
https://doaj.org/article/7986b1484d9d4e6cac836c9b612e4d93
Autor:
Brenda J. Andrews, Charles Boone, Quaid Morris, Patrick Aloy, Aleksei Shkurin, Ermira Shuteriqi, Myra Paz David Masinas, Matej Usaj, Carles Pons, Helena Friesen, Nil Sahin, Mojca Mattiazzi Usaj
Our ability to understand the genotype-to-phenotype relationship is hindered by the lack of detailed understanding of phenotypes at a single-cell level. To systematically assess cell-to-cell phenotypic variability, we combined automated yeast genetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4505e863eaa31d61b4a9b49192895d13
https://doi.org/10.32920/22149032.v1
https://doi.org/10.32920/22149032.v1
Autor:
Jolanda vanLeeuwen, Carles Pons, Guihong Tan, Jason Zi Wang, Jing Hou, Jochen Weile, Marinella Gebbia, Wendy Liang, Ermira Shuteriqi, Zhijian Li, Maykel Lopes, Matej Ušaj, Andreia Dos Santos Lopes, Natascha vanLieshout, Chad L Myers, Frederick P Roth, Patrick Aloy, Brenda J Andrews, Charles Boone
Publikováno v:
Molecular systems biology, vol. 16, no. 9, pp. e9828
Molecular Systems Biology
Molecular Systems Biology, Vol 16, Iss 9, Pp n/a-n/a (2020)
Molecular Systems Biology
Molecular Systems Biology, Vol 16, Iss 9, Pp n/a-n/a (2020)
Essential genes tend to be highly conserved across eukaryotes, but, in some cases, their critical roles can be bypassed through genetic rewiring. From a systematic analysis of 728 different essential yeast genes, we discovered that 124 (17%) were dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::50f331ae7fddb5c0cce1461560928eda
https://serval.unil.ch/notice/serval:BIB_E6E9FA206068
https://serval.unil.ch/notice/serval:BIB_E6E9FA206068
Autor:
Patrick Aloy, Brenda J. Andrews, Mojca Mattiazzi Usaj, Myra Paz David Masinas, Aleksei Shkurin, Matej Usaj, Carles Pons, Nil Sahin, Helena Friesen, Quaid Morris, Charles Boone, Ermira Shuteriqi
Endocytosis is a conserved process that mediates the internalization of nutrients and plasma membrane components, including receptors, for sorting to endosomes and the vacuole (lysosome). We combined systematic yeast genetics, high-content screening,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db7b64c56bd140bc5c0a035d85c0f7e3
Autor:
Carles Pons, Julia Hanchard, Hongwei Zhu, Daniel I. Bolnick, Brenda J. Andrews, Bryan Joseph San Luis, Elena Kuzmin, Matej Usaj, Michael Costanzo, Robbie Loewith, Wen Wang, Kaicong Xu, Amy A. Caudy, Michael Pryszlak, Chad L. Myers, Sara Sharifpoor, Yiqun Chen, Elizabeth N. Koch, Andrius J. Dagilis, Nydia Van Dyk, Benjamin VanderSluis, Margot Riggi, Guihong Tan, Ermira Shuteriqi, Mojca Mattiazzi Usaj, Raamesh Deshpande, Hamed Heydari, Attila Balint, Jason Zi Yang Wang, Charles Boone, Jolanda van Leeuwen, Grant W. Brown
Publikováno v:
Science (New York, N.Y.). 360(6386)
INTRODUCTION Genetic interactions occur when mutations in different genes combine to result in a phenotype that is different from expectation based on those of the individual mutations. Negative genetic interactions occur when a combination of mutati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cba155df06ecbf9111ed4cbb11edbff
https://pubmed.ncbi.nlm.nih.gov/29967502
https://pubmed.ncbi.nlm.nih.gov/29967502
Autor:
Gene Horecka, Andrew W. Murray, Lu Yang, Maria Pechlaner, John H. Koschwanez, Atina G. Cote, Brenda J. Andrews, Chris Oostenbrink, Michael Yuen, Pritpal Bansal, Todd R. Graham, Frederick P. Roth, Joseph C. Mellor, Anne-Claude Gingras, Natascha van Lieshout, Anastasia Baryshnikova, Claire E. Boone, Carles Pons, Helena Friesen, Kerry Andrusiak, Benjamin VanderSluis, Nicole Legro, Margaret McNee, Ji-Young Youn, Ermira Shuteriqi, Mehmet Takar, Elena Kuzmin, Chad L. Myers, Fatemeh Shaeri, Patrick Aloy, Matej Usaj, Jessica Cao, Michael Costanzo, Jolanda van Leeuwen, Wendy Liang, Song Sun, Marinella Gebbia, Bryan-Joseph San Luis, Mojca Mattiazzi Usaj, Ira Horecka, Takafumi N. Yamaguchi, Charles Boone
Publikováno v:
Scopus-Elsevier
A global genetic suppression network The genetic background of an organism can influence the overall effects of new genetic variants. Some mutations can amplify a deleterious phenotype, whereas others can suppress it. Starting with a literature surve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d287869e3ab9d4122ceef4cda146c86b
https://europepmc.org/articles/PMC5562937/
https://europepmc.org/articles/PMC5562937/
Autor:
Franco J. Vizeacoumar, Taras Makhnevych, Huiming Ding, Iain M. Wallace, Zhen Yuan Lin, Anne-Claude Gingras, Howard Bussey, Olga G. Troyanskaya, Robert P. St.Onge, Corey Nislow, Sara Mostafavi, Walid A. Houry, Amy Hin Yan Tong, Hongwei Zhu, Charles Boone, Balázs Papp, Michael Costanzo, Solmaz Alizadeh, Michael Brudno, Eric D. Spear, Chad L. Myers, Jeany Prinz, Guri Giaever, Bryan Joseph San Luis, Judice L. Y. Koh, Brenda J. Andrews, Yungil Kim, Gary D. Bader, Chris A. Kaiser, Jeremy Bellay, Kiana Toufighi, Csaba Pál, Joseph Whitney, Matthew T. Weirauch, Philip M. Kim, Carolyn S. Sevier, Wendy Liang, Guoqing Zhong, Murat Cokol, Frederick P. Roth, Yiqun Chen, Benjamin VanderSluis, Jadine Paw, Sondra Bahr, Ermira Shuteriqi, Michaela Marback, Raamesh Deshpande, Anastasia Baryshnikova, Renee L. Brost, Quaid Morris, Sasan Ragibizadeh, Zhijian Li, Nydia Van Dyk
Making Connections Genetic interaction profiles highlight cross-connections between bioprocesses, providing a global view of cellular pleiotropy, and enable the prediction of genetic network hubs. Costanzo et al. (p. 425 ) performed a pairwise fitnes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10f16e34230583fb261f74c66f41cf16
https://europepmc.org/articles/PMC5600254/
https://europepmc.org/articles/PMC5600254/