Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Erminio Clonfero"'
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 638:195-204
The influence of low-activity NER genotypes (XPC PAT−/+, XPA-A23G, XPD Asp312Asn, XPD Lys751Gln) and GSTM1 (active or null) was evaluated on anti-benzo[a]pyrene diol epoxide-(B[a]PDE)-DNA adduct formed in the lymphocyte plus monocyte fraction (LMF)
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 587:59-66
The functional significance of genetic polymorphisms on tobacco smoke-induced CYP1A2 activity was examined. The influence of three polymorphisms of the cytochrome P450 1A2 gene (CYP1A2) (-3860 G--A (allele *1C), -2467 T--delT (allele *1D), -163C--A (
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 558:53-62
The influence of the genetic deletion polymorphism of glutathione S-transferase micro 1 (GSTM1 *0/*0) on levels of anti (+/-)-r-7,t-8-dihydroxy-t-9,10-oxy-7,8,9,10-tetrahydrobenzo[a]pyrene (anti-BPDE-DNA) adduct in the peripheral blood lymphocyte plu
Autor:
Erminio Clonfero, Giovanni Milan, Sofia Pavanello, Guido Marcer, Giuseppe Mastrangelo, C. Veller Fornasa, Emanuela Fadda, Ugo Fedeli, M. Lazzaro
Publikováno v:
International Journal of Immunopathology and Pharmacology. 16:145-150
Inhalation of polyaromatic hydrocarbons (PAHs) extracted from diesel exhaust particles (DEP) enhances local (nasal) production of IgE in humans. The aim of the present research is to investigate whether in humans dermal exposure to PAHs which are not
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 521:1-9
In this study, the correlation of indicators of external (i.e. mean daily intake of condensate, nicotine, tobacco and tobacco proteins, and daily number of cigarettes smoked) and of internal tobacco-smoke exposure (i.e. urinary 1-pyrenol, nicotine an
Autor:
Erminio Clonfero, Renato Schieppati
Publikováno v:
Polycyclic Aromatic Compounds. 16:41-50
In Italy recycled oils are obtained by treating exhaust oils by deasphaltation, redistillation and subsequent thermal clay processing. PAH concentrations of intermediate and finished products were found to be 1200, 285, 420, and 275, 126 and 60 A. U.
Autor:
M. Pisoni, Lucia Celotti, Hans-Günter Neumann, Vito Foà, G. Brescia, Giovanni Maria Ferri, A. Forni, Giorgio Assennato, Erminio Clonfero
Publikováno v:
Archives of Toxicology. 73:431-439
The present study has the aim of evaluating gene-environment interaction on the levels of different biomarkers in coke-oven workers exposed to PAH. In order to assess whether the levels of some biomarkers (PAH-DNA adducts, nitro-PAH adducts to Hb and
Autor:
Ari Hirvonen, Erminio Clonfero, Lucia Celotti, Cristina Viezzer, Hannu Norppa, Giuseppe Mastrangelo, G Gabbani
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 431:259-269
To evaluate the influence of individual susceptibility factors on the level of polyaromatic (PAH) hydrocarbon DNA adducts and hypoxanthine guanine phosphoribosyl transferase (HPRT) mutants in peripheral lymphocytes, 70 coke-oven workers exposed to PA
Publikováno v:
Mutation Research/Genetic Toxicology. 368:283-291
Thirteen samples of used motor oil and 33 recycled fractions, obtained in the laboratory by means of a recovery process similar to that currently used in Italy (vacuum distillation followed by thermal clay treatment) were examined. The Ames test (sta
Publikováno v:
Mutagenesis. 11:207-211
Urine samples from 26 cigarette smokers on a restricteddiet were collected in the late afternoon. Urine extracts onXAD-2 resin were tested for mutagenicity in the microsusp-ension assay using Salmonella typhimurium strain TA98 inthe presence of metab