Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Erming Wang"'
Autor:
Claire Coleman, Minghui Wang, Erming Wang, Courtney Micallef, Zhiping Shao, James M. Vicari, Yuxin Li, Kaiwen Yu, Dongming Cai, Junmin Peng, Vahram Haroutunian, John F. Fullard, Jaroslav Bendl, Bin Zhang, Panos Roussos
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-12 (2023)
Abstract Alzheimer’s disease (AD) is the most common form of dementia worldwide, with a projection of 151 million cases by 2050. Previous genetic studies have identified three main genes associated with early-onset familial Alzheimer’s disease, h
Externí odkaz:
https://doaj.org/article/dfa8d2d44ad54e9fb041350fd615e5ac
Autor:
Erming Wang, Allen L. Pan, Pritha Bagchi, Srikant Rangaraju, Nicholas T. Seyfried, Michelle E. Ehrlich, Stephen R. Salton, Bin Zhang
Publikováno v:
Biomolecules, Vol 14, Iss 1, p 66 (2024)
DUSP4 is a member of the DUSP (dual-specificity phosphatase) subfamily that is selective to the mitogen-activated protein kinases (MAPK) and has been implicated in a range of biological processes and functions in Alzheimer’s disease (AD). In this s
Externí odkaz:
https://doaj.org/article/fecc5e04b41a42928c245a146df2ef3e
Autor:
Yuji Kajiwara, Erming Wang, Minghui Wang, Wun Chey Sin, Kristen J. Brennand, Eric Schadt, Christian C. Naus, Joseph Buxbaum, Bin Zhang
Publikováno v:
Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-20 (2018)
Abstract GJA1 (connexin43) has been predicted as the top key driver of an astrocyte enriched subnetwork associated with Alzheimer’s disease (AD). In this study, we comprehensively examined GJA1 expression across 29 transcriptomic and proteomic data
Externí odkaz:
https://doaj.org/article/977690558e094e1a87219300ec7b9707
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51266 (2012)
In this study, we have investigated the global impact of heterogeneous nuclear Ribonuclear Protein (hnRNP) H/F-mediated regulation of splicing events and gene expression in oligodendrocytes. We have performed a genome-wide transcriptomic analysis at
Externí odkaz:
https://doaj.org/article/3d4a74304c76478b8d7fccaf538887ff
Autor:
Erming Wang, Minghui Wang, Lei Guo, John F. Fullard, Courtney Micallef, Jaroslav Bendl, Won‐min Song, Chen Ming, Yong Huang, Yuxin Li, Kaiwen Yu, Junmin Peng, David A. Bennett, Philip L. De Jager, Panos Roussos, Vahram Haroutunian, Bin Zhang
Publikováno v:
Alzheimer's & Dementia.
Publikováno v:
Human molecular genetics. 31(R1)
Neurodegenerative diseases such as Alzheimer’s disease (AD) are characterized by the progressive loss of neurons in the brain and the spinal cord. The pathophysiology of AD is multifactorial with heterogeneous molecular manifestations. The lack of
Autor:
Chen Ming, Minghui Wang, Qian Wang, Ryan Neff, Erming Wang, Qi Shen, Joseph S. Reddy, Xue Wang, Mariet Allen, Nilüfer Ertekin‐Taner, Philip L. De Jager, David A. Bennett, Vahram Haroutunian, Eric Schadt, Bin Zhang
Publikováno v:
Alzheimer'sdementia : the journal of the Alzheimer's AssociationREFERENCES. 18(10)
A few copy number variations (CNVs) have been reported for Alzheimer's disease (AD). However, there is a lack of a systematic investigation of CNVs in AD based on whole genome sequencing (WGS) data.We used four methods to identify consensus CNVs from
Autor:
Wu Gang, Yuxin Li, Kuan Zeng, Bin Zhang, Junmin Peng, Qing Zhang, Vahram Haroutunian, Kaiwen Yu, Fang Huang, Xiaochuan Wang, Sezen Vatansever, Dan Ke, Jian-Zhi Wang, Minghui Wang, Rong Liu, Qun Wang, Xiang Gao, Erming Wang, Ryan Neff, Lei Guo, Yiyuan Xia
Background: 14-3-3ζ is overexpressed in brain regions affected by tau pathology in Alzheimer’s disease (AD), and its expression correlates with disease progression. The nuclear protein SET is a specific and efficient endogenous inhibitor of PP2A,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5de12b36b4156762234fd59f3742b8c6
https://doi.org/10.21203/rs.3.rs-744907/v1
https://doi.org/10.21203/rs.3.rs-744907/v1
Autor:
Bin Zhang, Erming Wang, Alan E. Renton, Minghui Wang, Alison Goate, Edoardo Marcora, Chen Ming
Publikováno v:
Alzheimer's & Dementia. 16
Autor:
Emrin Horgusluoglu-Moloch, Vahram Haroutunian, Lei Guo, Emilie L. Castranio, Valentina Fossati, Erming Wang, Sam Gandy, Chen Ming, Sezen Vatansever, Julia Tcw, Kristen J. Brennand, Won-Min Song, Qian Wang, Minghui Wang, Aiqun Li, Michelle E. Ehrlich, Bin Zhang, Dongming Cai, Scott Noggle, Alison Goate, Ryan Neff, Lap Ho, Eric E. Schadt, Pavel Katsel
Publikováno v:
Science Advances
Three major molecular subtypes of Alzheimer’s disease are identified, cross-validated, and characterized across 1543 individuals.
Alzheimer’s disease (AD), the most common form of dementia, is recognized as a heterogeneous disease with diver
Alzheimer’s disease (AD), the most common form of dementia, is recognized as a heterogeneous disease with diver