Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Ermin Gu"'
Autor:
Xinxin Chen1, Ermin Gu1, Shuanghu Wang2, Xiang Zheng1, Mengchun Chen1, Li Wang1 lxd54@163.com, Guoxin Hu1, Jian-ping Cai3, Hongyu Zhou1 zhouhy@wmu.edu.cn
Publikováno v:
Journal of Chromatographic Science. Mar2016, Vol. 54 Issue 3, p334-342. 9p.
Publikováno v:
Analytical Methods. 8:5025-5030
Isavuconazole (ISA) is a new generation, broad-spectrum triazole with efficacy against invasive fungal diseases including aspergillosis and mucormycosis. In this study, a rapid-resolution UPLC-MS/MS was developed for the determination of isavuconazol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d743cbc045fadd6067b4ae43110e4a7
https://doi.org/10.1039/c6ay00879h
https://doi.org/10.1039/c6ay00879h
Autor:
Guo-Xin Hu, Ermin Gu, Shuanghu Wang, Qiu-lei Chen, Bing-Qing Liang, Hong-Yu Zhou, Jian-Ping Cai, Yunyun Zhan, Da-Peng Dai
Publikováno v:
Pharmacology. 98:124-133
The objective of this study was to assess the catalytic activity of 22 novel CYP2D6 allelic variants (2D6*87-*98, R25Q, F164L, E215K, F219S, V327M, D336N, V342M, R344Q, R440C and R497C) to olanzapine in vitro. Their protein products expressed in Spod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3589ff74b77b70ea43e2fc5a4dbf7a39
https://doi.org/10.1159/000446807
https://doi.org/10.1159/000446807
Publikováno v:
Infection and Drug Resistance
Ren-ai Xu,1,* Er-min Gu,2,* Teng-hui Liu,3 Qiu-geng Ou-yang,3 Guo-xin Hu,3 Jian-ping Cai1,3 1Department of Pharmacy, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China; 2Department of Pharmacy, The First People’s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de7cf241cf26882203be62e3f285d432
https://www.dovepress.com/the-effects-of-cytochrome-p450-2c19-polymorphism-on-the-metabolism-of--peer-reviewed-article-IDR
https://www.dovepress.com/the-effects-of-cytochrome-p450-2c19-polymorphism-on-the-metabolism-of--peer-reviewed-article-IDR
Autor:
Bing-Qing Liang, Jian-Ping Cai, Yunyun Zhan, Ermin Gu, Da-Peng Dai, Guo-Xin Hu, Xiang-Xin Huang
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics. 41:759-765
Hemangeol, approved for the treatment of proliferative infantile hemangiomas requiring systemic therapy, is metabolized by cytochrome P450 2D6 (CYP2D6), which is a highly polymorphic enzyme that metabolizes a large number of drugs. More than 100 CYP2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::921a4595587556bc2f990661b6d5cbf7
https://doi.org/10.1007/s13318-015-0307-0
https://doi.org/10.1007/s13318-015-0307-0
Publikováno v:
Xenobiotica. 46:439-444
1. The objective of this study were to investigate the effect of orally administered resveratrol on the pharmacokinetics of aripiprazole (APZ) in rat, and the inhibitory effects of resveratrol on APZ dehydrogenation activity in liver microsomes and h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::721be9f1b23f741094dff21b23f6bad9
https://doi.org/10.3109/00498254.2015.1088175
https://doi.org/10.3109/00498254.2015.1088175
Publikováno v:
Journal of Chromatography B. 974:138-146
A rapid-resolution ultra high-performance liquid chromatography-tandem mass spectrometry separation method (UPLC-MS/MS) was developed for the simultaneous determination of carvedilol, and its three metabolites: 4'-hydroxyphenyl-carvedilol, 5'-hydroxy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0d20cba0c821751a2324465f413913a
https://doi.org/10.1016/j.jchromb.2014.10.037
https://doi.org/10.1016/j.jchromb.2014.10.037
Autor:
Bing-Qing Liang, Jian-Ping Cai, Guo-Xin Hu, Yan-Lin Feng, Da-Peng Dai, Yunyun Zhan, Ying Su, Ermin Gu, Xinxin Chen
Publikováno v:
Canadian journal of physiology and pharmacology. 94(8)
Cytochrome P450 enzyme 2D6 (CYP2D6) is an important member of the cytochrome P450 enzyme superfamily, with more than 100 CYP2D6 allelic variants being previously reported. The aim of this study was to assess the catalytic characteristics of 25 allele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5cc95dc71fef8a0a0e397e08454a332
https://pubmed.ncbi.nlm.nih.gov/27203132
https://pubmed.ncbi.nlm.nih.gov/27203132
Publikováno v:
Pharmacology. 97(1-2)
Objective: The aim of this article was to assess the catalytic activities of 24 cytochrome P450 2D6 (CYP2D6) variants found in the Chinese population toward atomoxetine in vitro as well as CYP2D6.1. Methods: In this study, the co-expression enzyme of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e8dc30d86568c00a41ecc6be0b4d7c2
https://pubmed.ncbi.nlm.nih.gov/26666748
https://pubmed.ncbi.nlm.nih.gov/26666748
Publikováno v:
Pharmacology. 96(3-4)
Objective: This study was conducted to investigate the effects of orally administered apigenin on the pharmacokinetics of venlafaxine (VEN) in rats and on the metabolism of VEN in human and rat liver microsomes in vitro. Methods: Ten healthy male SD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fbdb9b4d58eb8ae6d6684f7462ed82f
https://pubmed.ncbi.nlm.nih.gov/26202346
https://pubmed.ncbi.nlm.nih.gov/26202346