Výsledky vyhledávání - "Erlotinib Hydrochloride/therapeutic use"

Randomized phase III study of docetaxel versus docetaxel plus intercalated erlotinib in patients with relapsed non-squamous non-small cell lung carcinoma

Autor: Robert Peric, Vincent van der Noort, Harry J.M. Groen, Anne-Marie C. Dingemans, Nico van Walree, Franz M.N.H. Schramel, Christi M.J. Steendam, Pepijn Brocken, Stijn L.W. Koolen, G.D. Marijn Veerman, John W. G. van Putten, Ron H.J. Mathijssen, Egbert F. Smit, Joachim G.J.V. Aerts, Magdolen Youssef

Publikováno v: Lung Cancer, 160, 44-49. Elsevier Ireland Ltd
Lung Cancer, 160, 44-49. ELSEVIER IRELAND LTD

Background: Earlier preclinical and phase II research showed enhanced effect of docetaxel plus intercalated erlotinib. The NVALT-18 phase III study was designed to compare docetaxel with docetaxel plus intercalated erlotinib in relapsed metastasized

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f1412cde3a5dc0bde1bb210d253e089
https://doi.org/10.1016/j.lungcan.2021.08.002

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Tumor regression mediated by oncogene withdrawal or erlotinib stimulates infiltration of inflammatory immune cells in EGFR mutant lung tumors

Autor: Stellar Levy, Braden Miller, Curtis J. Perry, Susan M. Kaech, Alexandra Kuhlmann, Tianxia Guan, Fernando J. de Miguel, Daniel Zelterman, Camila Robles-Oteiza, Deborah Ayeni, William W. Lockwood, Ping-Chih Ho, Robert J. Homer, Katerina Politi, Mmaserame Gaefele, Gerald Krystal, Zongzhi Liu

Publikováno v: Journal for Immunotherapy of Cancer
Journal for immunotherapy of cancer, vol. 7, no. 1, pp. 172
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-15 (2019)

Background Epidermal Growth Factor Receptor (EGFR) tyrosine kinase inhibitors (TKIs) like erlotinib are effective for treating patients with EGFR mutant lung cancer; however, drug resistance inevitably emerges. Approaches to combine immunotherapies a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f2f07589f052ce53139b4376d5454b5
https://pubmed.ncbi.nlm.nih.gov/31291990

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