Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Erlinda Quijano"'
Publikováno v:
Cancer Gene Therapy. 12:691-698
Cultured primary human cells have been widely used to assess the selectivity of oncolytic viruses as potential anticancer agents. As culture conditions can potentially have a significant impact on virus replication and ultimately cell killing, we eva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7515c31324333744b73e7a8a1165386a
https://doi.org/10.1038/sj.cgt.7700840
https://doi.org/10.1038/sj.cgt.7700840
Autor:
Van Tsai, Heidrun Engler, Murali Ramachandra, Todd Machemer, Erlinda Quijano, Robert O. Ralston, Jennifer Philopena, Shu-Fen Wen
Publikováno v:
Virology. 328(1):52-61
Replication competent adenoviruses with various E1 modifications designed to restrict their replication to tumor cells are being evaluated as oncolytic agents in clinical trials. In mouse models, we observed that such oncolytic adenoviruses showed gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5ade00da62296166452f785176a1dbe
Autor:
David W. Kang, Monica L. Zepeda, Barry J. Sugarman, Erlinda Quijano, Danling Gu, L. David Looper
Publikováno v:
Molecular Therapy. 13
Excessive scarring is a significant clinical problem, resulting in both adverse tissue form and function. We have previously demonstrated that a recombinant adenovirus encoding the cyclin-dependent kinase inhibitor p21 (rAd-p21), attenuated cell prol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b418c3d2422ccaec4c21380ac5ad657
Autor:
Suzie H. Pun, Nathalie C. Bellocq, Thomas Schluep, Greg Jensen, Todd Machemer, Erlinda Quijano, Jeremy D. Heidel, Shu-Fen Wen, Heidrun Engler, Mark E. Davis, Aijie Liu
Publikováno v:
Bioconjugate chemistry. 15(4)
Linear and branched poly(ethylenimines), lPEI and bPEI, respectively, grafted with beta-cyclodextrin are prepared to give CD-lPEI and CD-bPEI, respectively, and are investigated as in vitro and in vivo nonviral gene delivery agents. The in vitro toxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c193284fa516872f7e1be7a1dec4b419
https://pubmed.ncbi.nlm.nih.gov/15264871
https://pubmed.ncbi.nlm.nih.gov/15264871
Autor:
G William, Demers, Duane E, Johnson, Van, Tsai, Shu-Fen, Wen, Erlinda, Quijano, Todd, Machemer, Jennifer, Philopena, Murali, Ramachandra, John A, Howe, Paul, Shabram, Robert, Ralston, Heidrun, Engler
Publikováno v:
Cancer research. 63(14)
Central to the development of oncolytic virotherapies for cancer will be a better understanding of the parameters that influence the outcome of virotherapy to treat disseminated cancer by i.v. administration versus regional disease by local treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::83592a1a8cdfa15617cde3e3c27d355d
https://pubmed.ncbi.nlm.nih.gov/12873998
https://pubmed.ncbi.nlm.nih.gov/12873998
Autor:
Thomas Schluep, Maneval Daniel, Alexis E Harper, Shu-Fen Wen, Todd Machemer, Susan E. Conroy, Erlinda Quijano, Heidrun Engler, Ken N. Wills
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy. 7(4)
We conducted a series of experiments to determine if intraperitoneal (IP) delivery of recombinant adenovirus (rAd)-based therapies is improved through carrier vehicle selection, and compared an icodextrin solution (a high molecular weight dextrin wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99ef2ff43f12b0960737642630d6c0dc
https://pubmed.ncbi.nlm.nih.gov/12727120
https://pubmed.ncbi.nlm.nih.gov/12727120
Autor:
Erlinda Quijano, Jeremy Shinoda, Shu Fen Wen, Yuetian Chen, Grace Michael, Ingo Runnenbaum, JoAnn Horowitz, Beth Hutchins, Mary Lynn Musco-Hobkinson, Dan Maneval, Tong-Yuan Yang, Vikas Mahavni, Richard E. Buller
Publikováno v:
Cancer gene therapy. 10(3)
A cohort study was designed to evaluate the efficiency of gene transfer and whether biological activity from the expressed therapeutic gene resulted after administration of a recombinant adenovirus containing the human wild-type p53 (p53(wt)) gene (r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b10e7e4872adcba81d34eb4d3a595df0
https://pubmed.ncbi.nlm.nih.gov/12637944
https://pubmed.ncbi.nlm.nih.gov/12637944
Autor:
Daniel C. Maneval, Christoph Huber, Jürgen Kuball, Derek Atkins, Grace Michael, Erlinda Quijano, Joachim W. Thüroff, Heidrun Engler, Mary Ann Fritz, Shu Fen Wen, Joachim Leissner, Beth Hutchins, S. Störkel, Patricia Meinhardt, Martin Schuler
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 20(4)
PURPOSE: To study safety, feasibility, and biologic activity of adenovirus-mediated p53 gene transfer in patients with bladder cancer. PATIENTS AND METHODS: Twelve patients with histologically confirmed bladder cancer scheduled for cystectomy were tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53c8a7f93c94054ff4015a53da35a757
https://pubmed.ncbi.nlm.nih.gov/11844817
https://pubmed.ncbi.nlm.nih.gov/11844817
Autor:
Erlinda Quijano, Danling Gu, David W. Kang, Monica L. Zepeda, David Looper, Shu Fen Wen, Diane McAllister
Publikováno v:
Molecular Therapy. 11:S290-S291
Understanding where genes are being expressed in normal, wounded and wound impaired skin, along with the duration of expression after transduction by recombinant adenovirus (rAd) is an important factor relevant to gene therapy strategies. Recombinant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73f55e2585a21cf6a7b64ab06a1abd39
https://doi.org/10.1016/j.ymthe.2005.07.289
https://doi.org/10.1016/j.ymthe.2005.07.289