Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Erlinda B. Santos"'
Autor:
Robin Peter, Brenda M. Sandmaier, Michael P. Dion, Sofia H. L. Frost, Erlinda B. Santos, Aimee Kenoyer, Donald K. Hamlin, D. Scott Wilbur, Robert D. Stewart, Darrell R. Fisher, Kai Vetter, Youngho Seo, Brian W. Miller
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Targeted radiopharmaceutical therapy with alpha-particle emitters (αRPT) is advantageous in cancer treatment because the short range and high local energy deposition of alpha particles enable precise radiation delivery and efficient tumor c
Externí odkaz:
https://doaj.org/article/19699be21fb4471dae94c49d02e265c3
Autor:
Brenda M. Sandmaier, Rainer Storb, Oliver W. Press, John M. Pagel, Aimee L. Kenoyer, Darrell R. Fisher, Erlinda B. Santos, Monica S. Thakar, Donald K. Hamlin, D. Scott Wilbur, Hirohisa Nakamae
Supplementary Methods from Biodistributions, Myelosuppression, and Toxicities in Mice Treated with an Anti-CD45 Antibody Labeled with the α-Emitting Radionuclides Bismuth-213 or Astatine-211
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dce4bc1a56ff690dac7633d44f676139
https://doi.org/10.1158/0008-5472.22381569
https://doi.org/10.1158/0008-5472.22381569
Autor:
Brenda M. Sandmaier, Rainer Storb, Oliver W. Press, John M. Pagel, Aimee L. Kenoyer, Darrell R. Fisher, Erlinda B. Santos, Monica S. Thakar, Donald K. Hamlin, D. Scott Wilbur, Hirohisa Nakamae
We previously investigated the potential of targeted radiotherapy using a bismuth-213 (213Bi)–labeled anti-CD45 antibody to replace total body irradiation as conditioning for hematopoietic cell transplantation in a canine model. Although this appro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f0b59d93b9c156f24be3f950484e841
https://doi.org/10.1158/0008-5472.c.6499911.v1
https://doi.org/10.1158/0008-5472.c.6499911.v1
Autor:
Brenda M. Sandmaier, Donald K. Hamlin, Huiying Qiu, Rainer Storb, Erlinda B. Santos, D. Scott Wilbur, Aya Nakaya
Publikováno v:
Transplant Cell Ther
In a canine model of pre-sensitization using donor blood transfusions, 100% of historical control dogs receiving 9.2 Gy total body irradiation (TBI) conditioning before dog leukocyte antigen (DLA)-identical marrow grafts had graft rejection. In this
Autor:
Eric Dorman, Manuela Matesan, Rainer Storb, Fatemeh Behnia, Margaret E. Nartea, Hubert Vesselle, Robyn Haaf, Brenda M. Sandmaier, Ted Gooley, Joseph G. Rajendran, Yawen Li, Johnnie J. Orozco, Michelle E. Bouvier, D. Scott Wilbur, Robert Emery, David H. Lewis, Kelsey Baker, Donald K. Hamlin, Erlinda B. Santos, Damian J. Green, Phuong Vo, Roger Wong
Publikováno v:
Transplantation and Cellular Therapy. 27:S54
Autor:
Brian W. Miller, Sofia H.L. Frost, Tom Bäck, Sue E. Knoblaugh, Aimee L. Kenoyer, Erlinda B. Santos, Brenda M. Sandmaier, Shani L. Frayo, Donald K. Hamlin, John M. Pagel, Rainer Storb, D. Scott Wilbur, Oliver W. Press
Publikováno v:
Journal of Nuclear Medicine. 56:1766-1773
α-radioimmunotherapy targeting CD45 may substitute for total-body irradiation in hematopoietic cell transplantation (HCT) preparative regimens for lymphoma. Our goal was to optimize the anti-CD45 monoclonal antibody (mAb; CA12.10C12) protein dose fo
Autor:
Sofia H.L. Frost, D. Scott Wilbur, Erlinda B. Santos, Brian W. Miller, Oliver W. Press, Johnnie J. Orozco, Donald K. Hamlin, Brenda M. Sandmaier, John M. Pagel, Damian J. Green, Darrell R. Fisher, Shani L. Frayo, Aimee L. Kenoyer, Jon C. Jones
Publikováno v:
Medical Physics. 42:4094-4105
Purpose: Alpha-emitting radionuclides exhibit a potential advantage for cancer treatments because they release large amounts of ionizing energy over a few cell diameters (50–80 μm), causing localized, irreparable double-strand DNA breaks that lead
Autor:
Brian C. Beard, Brenda M. Sandmaier, Devikha Chandrasekaran, Donald K. Hamlin, Erlinda B. Santos, D. Scott Wilbur, Hans-Peter Kiem, Christopher R. Burtner, Jennifer E. Adair
Publikováno v:
Human Gene Therapy. 26:399-406
Most hematopoietic stem cell gene therapy studies require host conditioning to allow for efficient engraftment of gene-modified cells. Conditioning regimens with lower treatment-related toxicities are especially relevant for the treatment of nonmalig
Autor:
Brenda M. Sandmaier, Ted Gooley, Fabio R. Kerbauy, Erlinda B. Santos, Rainer Storb, Wolfgang Bethge
Publikováno v:
Bone marrow transplantation
Extracorporeal photopheresis (ECP) and the purine analog pentostatin exert potent immunomodulatory effects. We evaluated the use of these treatment modalities to prevent GVHD in a canine model of unrelated dog leukocyte antigen mismatched hematopoiet
Publikováno v:
Chimerism. 4:95-101
Background: Although in vitro and in vivo experiments have suggested that mesenchymal stromal cells (MSC) may have important immunomodulatory functions in allogeneic hematopoietic cell transplantation (HCT), results from clinical studies have been in