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pro vyhledávání: '"Erlich, Alexander"'
Cells and tissues change shape both to carry out their function and during pathology. In most cases, these deformations are driven from within the systems themselves. This is permitted by a range of molecular actors, such as active crosslinkers and i
Externí odkaz:
http://arxiv.org/abs/2209.01440
Autor:
Erlich, Alexander, Recho, Pierre
The mechanism by which cells measure the dimension of the organ in which they are embedded, and slow down their growth when the final size is reached, is a long-standing problem of developmental biology. The role of mechanics in this feedback is cons
Externí odkaz:
http://arxiv.org/abs/2011.00486
In biological systems, the growth of cells, tissues, and organs is influenced by mechanical cues. Locally, cell growth leads to a mechanically heterogeneous environment as cells pull and push their neighbors in a cell network. Despite this local hete
Externí odkaz:
http://arxiv.org/abs/1904.11161
Publikováno v:
Interface Focus 9 (2019) 20190021
The primary exchange units in the human placenta are terminal villi, in which fetal capillary networks are surrounded by a thin layer of villous tissue, separating fetal from maternal blood. To understand how the complex spatial structure of villi in
Externí odkaz:
http://arxiv.org/abs/1902.08578
Autor:
Erlich, Alexander
Many living biological tissues are known to grow in response to their mechanical environment, such as changes in the surrounding pressure. This growth response can be seen, for instance, in the adaptation of heart chamber size and arterial wall thick
Externí odkaz:
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.729841
Autor:
Erlich, Alexander, Pearce, Philip, Mayo, Romina Plitman, Jensen, Oliver E., Chernyavsky, Igor L.
Publikováno v:
Science Advances 5 (2019) eaav6326
Across mammalian species, solute exchange takes place in complex microvascular networks. In the human placenta, the primary exchange units are terminal villi that contain disordered networks of fetal capillaries and are surrounded externally by mater
Externí odkaz:
http://arxiv.org/abs/1809.00749
Biological growth is often driven by mechanical cues, such as changes in external pressure or tensile loading. Moreover, it is well known that many living tissues actively maintain a preferred level of mechanical internal stress, called the mechanica
Externí odkaz:
http://arxiv.org/abs/1804.08107
Publikováno v:
Proceedings: Mathematical, Physical and Engineering Sciences, 2020 Jan 01. 476(2233), 1-16.
Externí odkaz:
https://www.jstor.org/stable/26917924
Akademický článek
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Publikováno v:
Nature Communications; 3/3/2023, Vol. 14 Issue 1, p1-16, 16p