Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Erkki Säkö"'
Autor:
Aarno Palotie, Petra Keski-Säntti, Maija Wessman, Mari A. Kaunisto, Matti Ilmavirta, Marja-Liisa Sumelahti, Salli Vepsäläinen, Marjo Eveliina Hiekkala, Paavo Häppölä, Eija Hämäläinen, Markus Färkkilä, Elisa Häppölä, Dennis Lal, E. Cuenca-Leon, Erkki Säkö, Hannele Havanka, Mikko Kallela, Padhraig Gormley, Ville Artto, Markku Nissilä, Pietari Vuola, Hanna Harno
Objective To study the position of hemiplegic migraine in the clinical spectrum of migraine with aura and to reveal the importance of CACNA1A, ATP1A2 and SCN1A in the development of hemiplegic migraine in Finnish migraine families. Methods The Intern
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::303866426aa32b7939ccbb7178d33b76
http://hdl.handle.net/10138/306611
http://hdl.handle.net/10138/306611
Autor:
Maija Wessman, Mitja I. Kurki, Aarno Palotie, Matti Ilmavirta, Salli Vepsäläinen, Hanna Harno, Mark J. Daly, Paavo Häppölä, Pekka Jousilahti, Verneri Anttila, Liisa Metsähonkala, Marja-Liisa Sumelahti, Markus Färkkilä, Mikko Kallela, Padhraig Gormley, Erkki Säkö, Marjo Eveliina Hiekkala, Benjamin M. Neale, Markku Nissilä, Priit Palta, Kumar Veerapen, Dennis Lal, Eija Hämäläinen, Jarmo Liukkonen, Hannele Havanka, Matti Sillanpää, Ville Artto, Heiko Runz, Adele A. Mitchell, Ida Surakka, Veikko Salomaa, Mari A. Kaunisto, Samuli Ripatti
It has long been observed that complex traits, including migraine, often aggregate in families, but the underlying genetic architecture behind this is not well understood. Two competing hypotheses exist, emphasizing either rare or common genetic vari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2309e8e697b8bab658edf5f03b9c5883
Autor:
Aarno Palotie, Suzanne M. Leal, Mikko Kallela, Hannele Havanka, Markus Färkkilä, Päivi J. Tikka, Jaakko Kaprio, Erkki Säkö, Markku Nissilä, Maija Wessman, Arja Korhonen, Matti Ilmavirta, Mari A. Kaunisto, Eija Hämäläinen, Roel A. Ophoff, Hanna Harno, Jeanette C. Papp
Publikováno v:
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. :85-89
Chromosomal area 19p13 contains two migraine associated genes: a Ca v 2.1 (P/Q-type) calcium channel α 1 subunit gene, CACNA1A, and an insulin receptor gene, INSR. Missense mutations in CACNA1A cause a rare Mendelian form of migraine, familial hemip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e851d6d9ebe978c3ab51419e39c8b2bb
https://doi.org/10.1002/ajmg.b.30082
https://doi.org/10.1002/ajmg.b.30082
Publikováno v:
Acta Neurologica Scandinavica. 69:232-233
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ec0d07e92a48976c1b81f9b3b23479b
https://doi.org/10.1111/j.1600-0404.1984.tb02453.x
https://doi.org/10.1111/j.1600-0404.1984.tb02453.x
Autor:
Leo Paljärvi, Raija Portin, Urpo K. Rinne, P. K. Mölsä, K. Laakso, Juha O. Rinne, Erkki Säkö, Jaakko Rinne
Publikováno v:
Acta Neurologica Scandinavica. 69:59-60
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::968535ca4cf7bd548bdb2e7d6ea2337d
https://doi.org/10.1111/j.1600-0404.1984.tb02389.x
https://doi.org/10.1111/j.1600-0404.1984.tb02389.x
Publikováno v:
Neuroscience letters. 161(1)
Brain [3H]Met- and [3H]Leu-enkephalin binding was studied in patients with Alzheimer's disease (AD) and vascular dementia (VD), and in age-matched controls. Brain areas investigated were the internal and external globus pallidus, amygdala, hippocampu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4938e7c60d6b807ea55c49f45cebe551
https://pubmed.ncbi.nlm.nih.gov/8255552
https://pubmed.ncbi.nlm.nih.gov/8255552
Autor:
Jarmo Hietala, Juha O. Rinne, A. Laihinen, Vesa Oikonen, Pertti Lehikoinen, Erkki Säkö, Kjell Någren, Erkka Syvälahti, Ulla Ruotsalainen
Publikováno v:
Europe PubMed Central
The effect of age on human striatal dopamine D2 receptors was investigated with positron emission tomography (PET) using [11C]raclopride as a radioligand. Twenty-one healthy volunteers aged from 20 to 81 years were studied. An equilibrium method was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab10e943e008d69fadb45130015cfaa8
https://pubmed.ncbi.nlm.nih.gov/8436624
https://pubmed.ncbi.nlm.nih.gov/8436624
Autor:
P. Lönnberg, Juha O. Rinne, Urpo K. Rinne, Leo Paljärvi, K. Laakso, Erkki Säkö, P. K. Mölsä, Jaakko Rinne
Publikováno v:
Brain Research. 336:19-25
Muscarinic receptors were analyzed in various post-mortem brain samples of 39 patients with different types of dementia and of 30 age-matched controls by the specific binding of [3H]QNB. The diagnoses were verified neuropathologically. The binding of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8508dfaadb100061a9ca3582cf02012e
https://doi.org/10.1016/0006-8993(85)90411-1
https://doi.org/10.1016/0006-8993(85)90411-1
Autor:
K. Pihlajamäki, Erkka Syvälahti, Mika Scheinin, Jarmo Hietala, Erkki Säkö, Risto Huupponen, Olli-Pekka Seppälä
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 9:441-449
1. 1. Two doses of apomorphine (0.005 mg/kg as a subcutaneous injection and 0.015 mg/kg as a 90 min i.v. infusion), and corresponding placebo treatments, were administered to 11 chronic medicated schizophrenic pa- tients and to 8 healthy control subj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6467c0021dbf2de789e8c6f1ad5db41
https://doi.org/10.1016/0278-5846(85)90198-8
https://doi.org/10.1016/0278-5846(85)90198-8
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 48:1085-1090
With neuropathological diagnosis as the point of reference, the accuracy of clinical diagnosis was studied in a series of 58 demented patients. Alzheimer's disease and multi-infarct dementia were recognised with sensitivities and specificities exceed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fe1d1dfde4ad1f81246435a7a92c1d2
https://doi.org/10.1136/jnnp.48.11.1085
https://doi.org/10.1136/jnnp.48.11.1085