Zobrazeno 1 - 10
of 395
pro vyhledávání: '"Erkers T"'
Autor:
Struyf N; Department of Oncology-Pathology, Karolinska Institutet, Science for Life Laboratory, Stockholm, Sweden. nona.struyf@ki.se., Österroos A; Department of Medical Sciences, Uppsala University Hospital, Uppsala, Sweden., Vesterlund M; Department of Oncology-Pathology, Karolinska Institutet, Science for Life Laboratory, Stockholm, Sweden., Arnroth C; Department of Oncology-Pathology, Karolinska Institutet, Science for Life Laboratory, Stockholm, Sweden., James T; Department of Oncology-Pathology, Karolinska Institutet, Science for Life Laboratory, Stockholm, Sweden., Sunandar S; Department of Oncology-Pathology, Karolinska Institutet, Science for Life Laboratory, Stockholm, Sweden., Mermelekas G; Department of Oncology-Pathology, Karolinska Institutet, Science for Life Laboratory, Stockholm, Sweden., Bohlin A; Department of Medicine, Center for Hematology and Regenerative Medicine, Karolinska Institute, Stockholm, Sweden., Hamberg Levedahl K; Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden., Bengtzén S; Department of Medicine, Center for Hematology and Regenerative Medicine, Karolinska Institute, Stockholm, Sweden., Jafari R; Department of Oncology-Pathology, Karolinska Institutet, Science for Life Laboratory, Stockholm, Sweden., Orre LM; Department of Oncology-Pathology, Karolinska Institutet, Science for Life Laboratory, Stockholm, Sweden., Lehtiö J; Department of Oncology-Pathology, Karolinska Institutet, Science for Life Laboratory, Stockholm, Sweden., Lehmann S; Department of Medical Sciences, Uppsala University Hospital, Uppsala, Sweden.; Department of Medicine, Center for Hematology and Regenerative Medicine, Karolinska Institute, Stockholm, Sweden., Östling P; Department of Oncology-Pathology, Karolinska Institutet, Science for Life Laboratory, Stockholm, Sweden., Kallioniemi O; Department of Oncology-Pathology, Karolinska Institutet, Science for Life Laboratory, Stockholm, Sweden.; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland., Seashore-Ludlow B; Department of Oncology-Pathology, Karolinska Institutet, Science for Life Laboratory, Stockholm, Sweden., Erkers T; Department of Oncology-Pathology, Karolinska Institutet, Science for Life Laboratory, Stockholm, Sweden. tom.erkers@ki.se.
Publikováno v:
NPJ precision oncology [NPJ Precis Oncol] 2024 Feb 19; Vol. 8 (1), pp. 38. Date of Electronic Publication: 2024 Feb 19.
Autor:
Bwanika HC; Department of Oncology and Pathology, Karolinska Institutet, Akademiska stråket 1, BioClinicum J6:14, 17164, Solna, Sweden., Leo IR; Department of Oncology and Pathology, Karolinska Institutet, Akademiska stråket 1, BioClinicum J6:14, 17164, Solna, Sweden.; Science for Life Laboratory, Solna, Sweden., Struyf N; Department of Oncology and Pathology, Karolinska Institutet, Akademiska stråket 1, BioClinicum J6:14, 17164, Solna, Sweden.; Science for Life Laboratory, Solna, Sweden., Talanti A; Department of Oncology and Pathology, Karolinska Institutet, Akademiska stråket 1, BioClinicum J6:14, 17164, Solna, Sweden., Aswad L; Department of Oncology and Pathology, Karolinska Institutet, Akademiska stråket 1, BioClinicum J6:14, 17164, Solna, Sweden.; Science for Life Laboratory, Solna, Sweden., Konnur A; Department of Oncology and Pathology, Karolinska Institutet, Akademiska stråket 1, BioClinicum J6:14, 17164, Solna, Sweden., Björklund AC; Department of Oncology and Pathology, Karolinska Institutet, Akademiska stråket 1, BioClinicum J6:14, 17164, Solna, Sweden.; Center for Hematology and Regenerative Medicine, Department of Medicine, Karolinska Institute, Huddinge, Sweden., Heyman M; Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden., Rassidakis G; Department of Oncology and Pathology, Karolinska Institutet, Akademiska stråket 1, BioClinicum J6:14, 17164, Solna, Sweden., Erkers T; Department of Oncology and Pathology, Karolinska Institutet, Akademiska stråket 1, BioClinicum J6:14, 17164, Solna, Sweden.; Science for Life Laboratory, Solna, Sweden., Seashore-Ludlow B; Department of Oncology and Pathology, Karolinska Institutet, Akademiska stråket 1, BioClinicum J6:14, 17164, Solna, Sweden.; Science for Life Laboratory, Solna, Sweden., Jafari R; Department of Oncology and Pathology, Karolinska Institutet, Akademiska stråket 1, BioClinicum J6:14, 17164, Solna, Sweden.; Science for Life Laboratory, Solna, Sweden., Pokrovskaja Tamm K; Department of Oncology and Pathology, Karolinska Institutet, Akademiska stråket 1, BioClinicum J6:14, 17164, Solna, Sweden. katja.pokrovskaja@ki.se.
Publikováno v:
Scientific reports [Sci Rep] 2024 Feb 18; Vol. 14 (1), pp. 4000. Date of Electronic Publication: 2024 Feb 18.
Autor:
Rosenquist R; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.; Clinical Genetics, Karolinska University Hospital, Solna, Stockholm, Sweden., Bernard E; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, USA.; PRISM Center for Personalized Medicine, Gustave Roussy, Villejuif, France., Erkers T; Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.; SciLifeLab, Stockholm, Sweden., Scott DW; BC Cancer's Centre for Lymphoid Cancer, Vancouver, Canada.; Department of Medicine, University of British Columbia, Vancouver, Canada., Itzykson R; Université Paris Cité, Génomes, biologie cellulaire et thérapeutique U944, INSERM, CNRS, Paris, France.; Département Hématologie et Immunologie, Hôpital Saint-Louis, Assistance Publique-Hôpitaux de Paris, Paris, France., Rousselot P; Department of Hematology, Centre Hospitalier de Versailles, Le Chesnay, France., Soulier J; Université Paris Cité, Génomes, biologie cellulaire et thérapeutique U944, INSERM, CNRS, Paris, France.; Hématologie Biologique, APHP, Hôpital Saint-Louis, Paris, France., Hutchings M; Department of Haematology and Phase 1 Unit, Rigshospitalet, Copenhagen, Denmark., Östling P; Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.; SciLifeLab, Stockholm, Sweden., Cavelier L; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.; Clinical Genetics, Karolinska University Hospital, Solna, Stockholm, Sweden., Fioretos T; Department of Clinical Genetics, Pathology and Molecular Diagnostics, Office for Medical Services, Region Skåne, Lund, Sweden.; Division of Clinical Genetics, Department of Laboratory Medicine, Lund University, Lund, Sweden.; Clinical Genomics Lund, Science for Life Laboratory, Lund University, Lund, Sweden., Smedby KE; Department of Hematology, Karolinska University Hospital, Solna, Stockholm, Sweden.; Division of Clinical Epidemiology, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.
Publikováno v:
Journal of internal medicine [J Intern Med] 2023 Oct; Vol. 294 (4), pp. 413-436. Date of Electronic Publication: 2023 Aug 07.
Autor:
Sanjiv, K., Calderón-Montaño, J.M., Pham, T.M., Erkers, T., Tsuber, V., Almlöf, I., Höglund, A., Heshmati, Y., Seashore-Ludlow, B., Nagesh Danda, A., Gad, H., Wiita, E., Göktürk, C., Rasti, A., Friedrich, S., Centio, A., Estruch, M., Våtsveen, T.K., Struyf, N., Visnes, T., Scobie, M., Koolmeister, T., Henriksson, M., Wallner, O., Sandvall, T., Lehmann, S., Theilgaard-Mönch, K., Garnett, M.J., Östling, P., Walfridsson, J., Helleday, T., Warpman Berglund, U.
Publikováno v:
Sanjiv, K, Calderón-Montaño, J M, Pham, T M, Erkers, T, Tsuber, V, Almlöf, I, Höglund, A, Heshmati, Y, Seashore-Ludlow, B, Nagesh Danda, A, Gad, H, Wiita, E, Göktürk, C, Rasti, A, Friedrich, S, Centio, A, Estruch, M, Våtsveen, T K, Struyf, N, Visnes, T, Scobie, M, Koolmeister, T, Henriksson, M, Wallner, O, Sandvall, T, Lehmann, S, Theilgaard-Mönch, K, Garnett, M J, Östling, P, Walfridsson, J, Helleday, T & Warpman Berglund, U 2021, ' MTH1 Inhibitor TH1579 Induces Oxidative DNA Damage and Mitotic Arrest in Acute Myeloid Leukemia ', Cancer Research, vol. 81, no. 22, pp. 5733-5744 . https://doi.org/10.1158/0008-5472.CAN-21-0061
Acute myeloid leukemia (AML) is an aggressive hematologic malignancy, exhibiting high levels of reactive oxygen species (ROS). ROS levels have been suggested to drive leukemogenesis and is thus a potential novel target for treating AML. MTH1 prevents
Autor:
Trac QT; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Pawitan Y; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Mou T; School of Biomedical Engineering, Shenzhen University, Shenzhen, China., Erkers T; Department of Oncology Pathology, Karolinska Institutet, Science for Life Laboratory, Stockholm, Sweden., Östling P; Department of Oncology Pathology, Karolinska Institutet, Science for Life Laboratory, Stockholm, Sweden.; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland., Bohlin A; Department of Medicine Huddinge, Karolinska Institutet, Unit for Hematology, Karolinska University Hospital Huddinge, Stockholm, Sweden., Österroos A; Department of Medical Sciences, Hematology, Uppsala University Hospital, Uppsala, Sweden., Vesterlund M; Department of Oncology Pathology, Karolinska Institutet, Science for Life Laboratory, Stockholm, Sweden., Jafari R; Department of Oncology Pathology, Karolinska Institutet, Science for Life Laboratory, Stockholm, Sweden., Siavelis I; Department of Oncology Pathology, Karolinska Institutet, Science for Life Laboratory, Stockholm, Sweden., Bäckvall H; Department of Oncology Pathology, Karolinska Institutet, Science for Life Laboratory, Stockholm, Sweden., Kiviluoto S; Department of Oncology Pathology, Karolinska Institutet, Science for Life Laboratory, Stockholm, Sweden., Orre LM; Department of Oncology Pathology, Karolinska Institutet, Science for Life Laboratory, Stockholm, Sweden., Rantalainen M; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Lehtiö J; Department of Oncology Pathology, Karolinska Institutet, Science for Life Laboratory, Stockholm, Sweden., Lehmann S; Department of Medicine Huddinge, Karolinska Institutet, Unit for Hematology, Karolinska University Hospital Huddinge, Stockholm, Sweden.; Department of Medical Sciences, Hematology, Uppsala University Hospital, Uppsala, Sweden., Kallioniemi O; Department of Oncology Pathology, Karolinska Institutet, Science for Life Laboratory, Stockholm, Sweden.; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland., Vu TN; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. trungnghia.vu@ki.se.
Publikováno v:
NPJ precision oncology [NPJ Precis Oncol] 2023 Mar 24; Vol. 7 (1), pp. 32. Date of Electronic Publication: 2023 Mar 24.
Autor:
Jädersten M; Department of Hematology, Karolinska University Hospital, Stockholm, Sweden.; Center for Hematology and Regenerative Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden., Lilienthal I; Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden., Tsesmetzis N; Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden., Lourda M; Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.; Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden., Bengtzén S; Center for Hematology and Regenerative Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden., Bohlin A; Center for Hematology and Regenerative Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden., Arnroth C; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden., Erkers T; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden., Seashore-Ludlow B; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden., Giraud G; Department of Immunology, Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden.; Department of Pediatric Oncology, Akademiska Children's Hospital, Uppsala University Hospital, Uppsala, Sweden., Barkhordar GS; Department of Clinical Genetics and Genomics, Sahlgrenska University Hospital, Gothenburg, Sweden., Tao S; Department of Pediatrics, School of Medicine, Emory University, Atlanta, Georgia, USA., Fogelstrand L; Department of Clinical Chemistry, Sahlgrenska University Hospital, Gothenburg, Sweden.; Department of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden., Saft L; Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden.; Department of Clinical Pathology and Cancer Diagnostics, Karolinska University Hospital, Stockholm, Sweden., Östling P; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden., Schinazi RF; Department of Pediatrics, School of Medicine, Emory University, Atlanta, Georgia, USA., Kim B; Department of Pediatrics, School of Medicine, Emory University, Atlanta, Georgia, USA., Schaller T; Department of Infectious Diseases, University Hospital Heidelberg, Heidelberg, Germany., Juliusson G; Department of Hematology, Skåne University Hospital, Lund, Sweden.; Stem Cell Center, Department of Hematology, Department of Laboratory Medicine, Lund University, Lund, Sweden., Deneberg S; Department of Hematology, Karolinska University Hospital, Stockholm, Sweden.; Center for Hematology and Regenerative Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden., Lehmann S; Center for Hematology and Regenerative Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.; Department of Medical Sciences, Uppsala University, Uppsala, Sweden., Rassidakis GZ; Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden.; Department of Clinical Pathology and Cancer Diagnostics, Karolinska University Hospital, Stockholm, Sweden., Höglund M; Department of Medical Sciences, Uppsala University, Uppsala, Sweden., Henter JI; Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.; Department of Paediatric Oncology, Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden., Herold N; Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.; Department of Paediatric Oncology, Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden.
Publikováno v:
Journal of internal medicine [J Intern Med] 2022 Dec; Vol. 292 (6), pp. 925-940. Date of Electronic Publication: 2022 Aug 18.
Autor:
Pérez-Cruz M; Division of Blood and Marrow Transplantation, Department of Medicine, Stanford University School of Medicine, Stanford, CA, United States., Iliopoulou BP; Division of Blood and Marrow Transplantation, Department of Medicine, Stanford University School of Medicine, Stanford, CA, United States., Hsu K; Division of Blood and Marrow Transplantation, Department of Medicine, Stanford University School of Medicine, Stanford, CA, United States., Wu HH; Division of Blood and Marrow Transplantation, Department of Medicine, Stanford University School of Medicine, Stanford, CA, United States., Erkers T; Division of Blood and Marrow Transplantation, Department of Medicine, Stanford University School of Medicine, Stanford, CA, United States., Swaminathan K; Division of Blood and Marrow Transplantation, Department of Medicine, Stanford University School of Medicine, Stanford, CA, United States., Tang SW; Division of Blood and Marrow Transplantation, Department of Medicine, Stanford University School of Medicine, Stanford, CA, United States., Bader CS; Division of Blood and Marrow Transplantation, Department of Medicine, Stanford University School of Medicine, Stanford, CA, United States., Kambham N; Department of Developmental biology, Stanford University School of Medicine, Stanford, CA, United States., Xie B; Division of Blood and Marrow Transplantation, Department of Medicine, Stanford University School of Medicine, Stanford, CA, United States., Dekruyff RH; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, United States., Freeman GJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, United States., Meyer E; Division of Blood and Marrow Transplantation, Department of Medicine, Stanford University School of Medicine, Stanford, CA, United States.
Publikováno v:
Frontiers in immunology [Front Immunol] 2022 Nov 07; Vol. 13, pp. 960329. Date of Electronic Publication: 2022 Nov 07 (Print Publication: 2022).
Publikováno v:
Bone Marrow Transplantation. Jun2014, Vol. 49 Issue 6, p737-743. 7p.
Autor:
Leo IR; Clinical Proteomics Mass Spectrometry, Department of Oncology-Pathology, Karolinska Institutet, Science for Life Laboratory, Tomtebodavägen 23A, 171 65, Solna, Sweden., Aswad L; Clinical Proteomics Mass Spectrometry, Department of Oncology-Pathology, Karolinska Institutet, Science for Life Laboratory, Tomtebodavägen 23A, 171 65, Solna, Sweden., Stahl M; Clinical Proteomics Mass Spectrometry, Department of Oncology-Pathology, Karolinska Institutet, Science for Life Laboratory, Tomtebodavägen 23A, 171 65, Solna, Sweden., Kunold E; Clinical Proteomics Mass Spectrometry, Department of Oncology-Pathology, Karolinska Institutet, Science for Life Laboratory, Tomtebodavägen 23A, 171 65, Solna, Sweden., Post F; Clinical Proteomics Mass Spectrometry, Department of Oncology-Pathology, Karolinska Institutet, Science for Life Laboratory, Tomtebodavägen 23A, 171 65, Solna, Sweden.; Institute of Plant Biology and Biotechnology, University of Muenster, Schlossplatz 7, 48149, Muenster, Germany., Erkers T; Molecular Precision Medicine, Department of Oncology-Pathology, Karolinska Institutet, Science for Life Laboratory, Tomtebodavägen 23A, 171 65, Solna, Sweden., Struyf N; Molecular Precision Medicine, Department of Oncology-Pathology, Karolinska Institutet, Science for Life Laboratory, Tomtebodavägen 23A, 171 65, Solna, Sweden., Mermelekas G; Clinical Proteomics Mass Spectrometry, Department of Oncology-Pathology, Karolinska Institutet, Science for Life Laboratory, Tomtebodavägen 23A, 171 65, Solna, Sweden., Joshi RN; Clinical Proteomics Mass Spectrometry, Department of Oncology-Pathology, Karolinska Institutet, Science for Life Laboratory, Tomtebodavägen 23A, 171 65, Solna, Sweden., Gracia-Villacampa E; Division of Gene Technology, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH, Science for Life Laboratory, Tomtebodavägen 23A, 171 65, Solna, Sweden., Östling P; Molecular Precision Medicine, Department of Oncology-Pathology, Karolinska Institutet, Science for Life Laboratory, Tomtebodavägen 23A, 171 65, Solna, Sweden., Kallioniemi OP; Molecular Precision Medicine, Department of Oncology-Pathology, Karolinska Institutet, Science for Life Laboratory, Tomtebodavägen 23A, 171 65, Solna, Sweden., Tamm KP; Department of Oncology-Pathology, Karolinska Institutet, J6:140 BioClinicum, Akademiska stråket 1, 171 64, Solna, Sweden., Siavelis I; Clinical Proteomics Mass Spectrometry, Department of Oncology-Pathology, Karolinska Institutet, Science for Life Laboratory, Tomtebodavägen 23A, 171 65, Solna, Sweden., Lehtiö J; Clinical Proteomics Mass Spectrometry, Department of Oncology-Pathology, Karolinska Institutet, Science for Life Laboratory, Tomtebodavägen 23A, 171 65, Solna, Sweden., Vesterlund M; Clinical Proteomics Mass Spectrometry, Department of Oncology-Pathology, Karolinska Institutet, Science for Life Laboratory, Tomtebodavägen 23A, 171 65, Solna, Sweden., Jafari R; Clinical Proteomics Mass Spectrometry, Department of Oncology-Pathology, Karolinska Institutet, Science for Life Laboratory, Tomtebodavägen 23A, 171 65, Solna, Sweden. rozbeh.jafari@ki.se.
Publikováno v:
Nature communications [Nat Commun] 2022 Mar 30; Vol. 13 (1), pp. 1691. Date of Electronic Publication: 2022 Mar 30.
Publikováno v:
Clinical & Experimental Immunology. Mar2012, Vol. 167 Issue 3, p543-555. 13p. 1 Black and White Photograph, 5 Graphs.