Towards a functional cure for chronic hepatitis B

Autor: Erken, R.

Chronic hepatitis B (CHB) is an infectious disease caused by the bloodborne hepatitis B virus in patients that do not spontaneously clear the virus after infection. The virus affects the liver and can lead to hepatitis, liver cirrhosis and livercance

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Quantified integrated hepatitis B virus is related to viral activity in patients with chronic hepatitis B.

Autor: Erken R; Department of Experimental Immunology, Amsterdam UMC, location AMC, Amsterdam Infection & Immunity Institute, University of Amsterdam, Amsterdam, the Netherlands.; Department of Gastroenterology and Hepatology, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam UMC, location AMC, Amsterdam, the Netherlands., Loukachov V; Department of Experimental Immunology, Amsterdam UMC, location AMC, Amsterdam Infection & Immunity Institute, University of Amsterdam, Amsterdam, the Netherlands., van Dort K; Department of Experimental Immunology, Amsterdam UMC, location AMC, Amsterdam Infection & Immunity Institute, University of Amsterdam, Amsterdam, the Netherlands., van den Hurk A; Department of Experimental Immunology, Amsterdam UMC, location AMC, Amsterdam Infection & Immunity Institute, University of Amsterdam, Amsterdam, the Netherlands., Takkenberg RB; Department of Gastroenterology and Hepatology, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam UMC, location AMC, Amsterdam, the Netherlands., de Niet A; Department of Gastroenterology and Hepatology, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam UMC, location AMC, Amsterdam, the Netherlands., Jansen L; Department of Gastroenterology and Hepatology, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam UMC, location AMC, Amsterdam, the Netherlands., Willemse S; Department of Gastroenterology and Hepatology, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam UMC, location AMC, Amsterdam, the Netherlands., Reesink H; Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, the Netherlands., Kootstra N; Department of Experimental Immunology, Amsterdam UMC, location AMC, Amsterdam Infection & Immunity Institute, University of Amsterdam, Amsterdam, the Netherlands.

Publikováno v: Hepatology (Baltimore, Md.) [Hepatology] 2022 Jul; Vol. 76 (1), pp. 196-206. Date of Electronic Publication: 2022 Feb 14.

A Prospective Five-Year Follow-up After peg-Interferon Plus Nucleotide Analogue Treatment or no Treatment in HBeAg Negative Chronic Hepatitis B Patients.

Autor: Erken R; Amsterdam UMC, University of Amsterdam, Department of Gastroenterology and Hepatology, Amsterdam Gastroenterology Endocrinology Metabolism, Meibergdreef 9, Amsterdam, the Netherlands., Loukachov VV; Department of Experimental Immunology, Amsterdam UMC, Location AMC, Meibergdreef 9, 1105AZ, Amsterdam, the Netherlands., de Niet A; Department of Gastroenterology and Hepatology, Amsterdam UMC, Location AMC, Meibergdreef 9, 1105AZ, Amsterdam, the Netherlands., Jansen L; Department of Gastroenterology and Hepatology, Amsterdam UMC, Location AMC, Meibergdreef 9, 1105AZ, Amsterdam, the Netherlands., Stelma F; Department of Gastroenterology and Hepatology, Amsterdam UMC, Location AMC, Meibergdreef 9, 1105AZ, Amsterdam, the Netherlands., Helder JT; Department of Gastroenterology and Hepatology, Amsterdam UMC, Location AMC, Meibergdreef 9, 1105AZ, Amsterdam, the Netherlands., Peters MW; Department of Gastroenterology and Hepatology, Amsterdam UMC, Location AMC, Meibergdreef 9, 1105AZ, Amsterdam, the Netherlands., Zaaijer HL; Sanquin Blood Supply Foundation, Plesmanlaan 125, Amsterdam, the Netherlands., Kootstra NA; Department of Experimental Immunology, Amsterdam UMC, Amsterdam Infection & Immunity Institute, University of Amsterdam, Amsterdam, the Netherlands., Willemse SB; Amsterdam UMC, University of Amsterdam, Department of Gastroenterology and Hepatology, Amsterdam Gastroenterology Endocrinology Metabolism, Meibergdreef 9, Amsterdam, the Netherlands., Reesink HW; Amsterdam UMC, University of Amsterdam, Department of Gastroenterology and Hepatology, Amsterdam Gastroenterology Endocrinology Metabolism, Meibergdreef 9, Amsterdam, the Netherlands.

Publikováno v: Journal of clinical and experimental hepatology [J Clin Exp Hepatol] 2022 May-Jun; Vol. 12 (3), pp. 735-744. Date of Electronic Publication: 2022 Jan 04.

Hepatitis B core related antigen in relation to intrahepatic and circulating viral markers, before and after combination therapy.

Autor: Erken R; Department of Gastroenterology and Hepatology, Amsterdam Gastroenterology Endocrinology Metabolism; Medical Microbiology, Academic Medical Center, Amsterdam, The Netherlands. Electronic address: r.erken@amsterdamumc.nl., Zaaijer HL; Medical Microbiology, Academic Medical Center, Amsterdam, The Netherlands. Electronic address: h.l.zaaijer@amsterdamumc.nl., Willemse SB; Department of Gastroenterology and Hepatology, Amsterdam Gastroenterology Endocrinology Metabolism. Electronic address: s.b.willemse@amsterdamumc.nl., Bakker E; Sanquin Blood Supply Foundation, Plesmanlaan 125, Amsterdam, the Netherlands.. Electronic address: e.bakker@sanquin.nl., Takkenberg BB; Department of Gastroenterology and Hepatology, Amsterdam Gastroenterology Endocrinology Metabolism. Electronic address: r.b.takkenberg@amsterdamumc.nl., Reesink HW; Amsterdam UMC, location AMC, Meibergdreef 9, Amsterdam, the Netherlands. Electronic address: h.w.reesink@lumc.nl., Kootstra NA; Department of Experimental Immunology, Amsterdam UMC, Amsterdam Infection & Immunity Institute, University of Amsterdam, Amsterdam, Netherlands.. Electronic address: n.a.kootstra@amc.uva.nl.

Publikováno v: Annals of hepatology [Ann Hepatol] 2021 Dec; Vol. 26, pp. 100540. Date of Electronic Publication: 2021 Sep 25.