Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Eriya Kenjo"'
Autor:
Eriya Kenjo, Hiroyuki Hozumi, Yukimasa Makita, Kumiko A. Iwabuchi, Naoko Fujimoto, Satoru Matsumoto, Maya Kimura, Yuichiro Amano, Masataka Ifuku, Youichi Naoe, Naoto Inukai, Akitsu Hotta
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
In vivo delivery of CRISPR-Cas9 holds promise for treating muscular dystrophy, however, AAV delivery is known to be immunogenic. Here, the authors show that LNP delivery of CRISPR-Cas9 enables repeated injections into skeletal muscle and leads to res
Externí odkaz:
https://doaj.org/article/82ba1424688643b8923145dd7be8e610
Autor:
Shoko Takeuchi, Mitsuo Yamamoto, Satoru Matsumoto, Eriya Kenjo, Masatoshi Karashima, Yukihiro Ikeda
Publikováno v:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 1192
The clustered regularly interspaced short palindromic repeats-CRISPR associated protein9 (CRISPR-Cas9) system, which includes a single guide RNA (sgRNA) and a Cas9 protein, is an emerging and promising gene editing technology that produces specific c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::885a372f46f4f5d3a61cf1c759bf5e84
https://pubmed.ncbi.nlm.nih.gov/35139474
https://pubmed.ncbi.nlm.nih.gov/35139474
Autor:
Mamoru Nango, Naoto Oku, Norihito Yonenaga, Takehisa Dewa, Eriya Kenjo, Tomohiro Asai, Atsushi Tsuruta, Kosuke Shimizu
Publikováno v:
Journal of Controlled Release. 160:177-181
For the purpose of systemic delivery of siRNA, we previously developed polycation liposomes (PCLs) containing dicetylphosphate-tetraethylenepentamine (DCP-TEPA) as an effective siRNA carrier. In the present study, to endow these PCLs (TEPA-PCL) activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5599f8310d5d359503ca55f621545f8
https://doi.org/10.1016/j.jconrel.2011.10.004
https://doi.org/10.1016/j.jconrel.2011.10.004
Autor:
Takehisa Dewa, Hiroshi Kikuchi, Takuma Tsuzuku, Kentaro Hatanaka, Hiroyuki Koide, Saori Matsushita, Tomohiro Asai, Noriyuki Maeda, Naoto Oku, Eriya Kenjo, Norihito Yonenaga, Mamoru Nango
Publikováno v:
Bioconjugate Chemistry. 22:429-435
Dicetyl phosphate-tetraethylenepentamine (DCP-TEPA) conjugate was newly synthesized and formed into liposomes for efficient siRNA delivery. Formulation of DCP-TEPA-based polycation liposomes (TEPA-PCL) complexed with siRNA was examined by performing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::560446b78a07035e59b485b0a372f912
https://doi.org/10.1021/bc1004697
https://doi.org/10.1021/bc1004697
Autor:
Kentaro Hatanaka, Eriya Kenjo, Hiroyuki Koide, Hideo Tsukada, Tomohiro Asai, Naoto Oku, Norihiro Harada, Takuma Tsuzuku
Publikováno v:
Bioconjugate Chemistry. 21:756-763
Pharmacokinetic study of small interfering RNA (siRNA) is an important issue for the development of siRNAs for use as a medicine. For this purpose, a novel and favorable positron emitter-labeled siRNA was prepared by amino group-modification using N-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::710f01d66b0c8293bb43e4bc0305fd5d
https://doi.org/10.1021/bc9005267
https://doi.org/10.1021/bc9005267
Autor:
Hiroyuki Koide, Naoto Oku, Eriya Kenjo, Takeo Urakami, Masamichi Nishihara, Masayuki Yokoyama, Hiroshi Kiwada, Takayuki Ishii, Kentaro Hatanaka, Tomohiro Asai, Tatsuhiro Ishida
Publikováno v:
International Journal of Pharmaceutics. 362:197-200
A repeat-injection of polyethylene glycol-modified liposomes (PEGylated liposomes) causes a rapid clearance of them from the blood circulation in certain cases that is referred to as the accelerated blood clearance (ABC) phenomenon. In the present st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d23832069209524c4190994a128538eb
https://doi.org/10.1016/j.ijpharm.2008.06.004
https://doi.org/10.1016/j.ijpharm.2008.06.004
Autor:
Naoto Oku, Takayuki Ishii, Hidenori Ando, Yugo Urita, Hideo Tsukada, Tomohiro Asai, Norihito Yonenaga, Takehisa Dewa, Kentaro Hatanaka, Kosuke Shimizu, Eriya Kenjo, Mamoru Nango
Publikováno v:
Biologicalpharmaceutical bulletin. 36(2)
Novel polycation liposomes decorated with cyclic(Cys-Arg-Gly-Asp-D-Phe) peptide (cyclicRGD)-polyethylene glycol (PEG) (RGD-PEG-polycation liposomes (PCL)) were previously developed for cancer therapy based on RNA interference. Here, we demonstrate th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8161c5d7f39ac2aeee5cc3a37fbd9ed
https://pubmed.ncbi.nlm.nih.gov/23370357
https://pubmed.ncbi.nlm.nih.gov/23370357
Autor:
Takayuki Ishii, Hiroshi Kiwada, Hideo Tsukada, Tatsuhiro Ishida, Shuji Akai, Eriya Kenjo, Naoto Oku, Tomohiro Asai, Kentaro Hatanaka, Hiroyuki Koide
Publikováno v:
International journal of pharmaceutics. 392(1-2)
Repeated injection of polyethyleneglycol-modified (PEGylated) liposomes causes a rapid clearance of them from the bloodstream, this phenomenon is called accelerated blood clearance (ABC). In the present study, we focused on the immune system responsi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::815546308f667f860efa8965e7bdd460
https://pubmed.ncbi.nlm.nih.gov/20227473
https://pubmed.ncbi.nlm.nih.gov/20227473
Autor:
Tomohiro Asai, Saori Matsushita, Eriya Kenjo, Takuma Tsuzuku, Norihito Yonenaga, Hiroyuki Koide, Kentaro Hatanaka, Takehisa Dewa, Mamoru Nango, Noriyuki Maeda, Hiroshi Kikuchi, Naoto Oku
Publikováno v:
Bioconjugate Chemistry; Mar2011, Vol. 22 Issue 3, p429-435, 7p