Výsledky vyhledávání - "Erina Sakamoto"

Analysis of elderly patients with diffuse large B-cell lymphoma: aggressive therapy is a reasonable approach for ‘unfit’ patients classified by comprehensive geriatric assessment

Autor: Manabu Hirai, Masayuki Hino, Takafumi Nakao, Hideya Ueda, Takahisa Yamane, Hideo Koh, Takahiko Nakane, Masahiro Yoshida, Erina Sakamoto, Kiyoyuki Hagihara, Takeshi Inoue, Mirei Horiuchi, Hiroshi Kanashima

Publikováno v: European Journal of Haematology. 96:409-416

Background The treatment strategy for diffuse large B-cell lymphoma (DLBCL) in elderly patients is problematic. Although several researchers have reported the effectiveness of comprehensive geriatric assessment (CGA) and the futility of curative trea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc922e60da953d5093045c64b60f68a7
https://doi.org/10.1111/ejh.12608

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SRY and OCT4 Are Required for the Acquisition of Cancer Stem Cell-Like Properties and Are Potential Differentiation Therapy Targets

Autor: Wataru Ninomiya, Tatsuhiro Shibata, Hirotada Akiyama, Fumio Tashiro, Erina Sakamoto, Shigekazu Murakami

Publikováno v: Stem Cells. 33:2652-2663

The acquisition of stemness is a hallmark of aggressive human hepatocellular carcinoma (hHCC). The stem cell marker OCT4 is frequently expressed in HCCs, and its expression correlates with those of putative cancer stem cell (CSC) markers and CSC prop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6323259c671937c8eea56daae17a526
https://doi.org/10.1002/stem.2059

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High calorie diet augments age-associated sleep impairment in Drosophila

Autor: Kazuhiro Takahama, Madoka Mitsuyoshi, Kazuhiko Kume, Taro Ueno, Masako Yamazaki, Jun Tomita, Shoen Kume, Erina Sakamoto

Publikováno v: Biochemical and Biophysical Research Communications. 417(No. 2):812-816

The fruit fly, Drosophila melanogaster is an established model used for aging and longevity studies and more recently for sleep studies. Mammals and Drosophila share various physiological, pathological, pharmacological and genetic similarities in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fe259b0a1f4d2db71ab425ffd2e043e
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100713334

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Precursor B-lymphoblastic Lymphoma Involving an Intracardiac Mass and Myocardial Infiltration: A Case Report

Autor: Hiroko Fukushima, Erina Sakamoto, Satoru Mukai, Takafumi Nakao, Takahisa Yamane, Hirofumi Teshima, Takeshi Inoue, Yuki Kubo, Hiroshi Kanashima, Yumi Yoshii, Masahiro Manabe

Publikováno v: Internal Medicine. 51:315-319

We report the case of a 17-year-old man with precursor B-lymphoblastic lymphoma involving an intracardiac mass and myocardial infiltration. Intensified chemotherapy followed by autologous peripheral blood stem cell transplantation resulted in long-te

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c035ac1b9d0434a640556dc55dc410d1
https://doi.org/10.2169/internalmedicine.51.6075

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Efficacy and safety of intravenous itraconazole as empirical antifungal therapy for persistent fever in neutropenic patients with hematological malignancies in Japan

Autor: Hideo Koh, Yasunobu Takeoka, Yoshitaka Nakao, Takahiko Nakane, Masayuki Hino, Yukari Umemoto, Ryousuke Yamamura, Shuichiro Okamoto, Saori Kosaka, Yoshiki Terada, Asao Hirose, Erina Sakamoto, Kensuke Ohta, Yasutaka Aoyama, Kiyomichi Hagihara, Takeo Kumura, Yoshiki Hayashi

Publikováno v: International Journal of Hematology. 89:649-655

Recently, empirical antifungal therapy with intravenous itraconazole (ITCZ) for neutropenic patients with antibiotics-resistant fever has been approved by Japanese Ministry of Health, Labour and Welfare on the bases of previous multicenter trials of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76e095289eeababeb03997500235b52b
https://doi.org/10.1007/s12185-009-0316-3

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Enhanced neutrophil motility by granulocyte colony-stimulating factor: the role of extracellular signal-regulated kinase and phosphatidylinositol 3-kinase

Autor: Fumihiko Hato, Sayuri Masuda, Haruo Kutsuna, Seiichi Kitagawa, Masayuki Hino, Mika Nakamae-Akahori, Erina Sakamoto, Yoshiki Nishizawa, Takayuki Kato

Publikováno v: Immunology. 119:393-403

The effect of granulocyte colony-stimulating factor (G-CSF) on human neutrophil motility was studied using videomicroscopy. Stimulation of neutrophils with G-CSF resulted in enhanced motility with morphological change and increased adherence. Enhance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b9cd62a9820c95e2da4bb01be84a669
https://doi.org/10.1111/j.1365-2567.2006.02448.x

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Regulation of neutrophil apoptosis by cytokines: Role of IAP family

Autor: Seiichi Kitagawa, Takayuki Kato, Fumihiko Hato, Erina Sakamoto

Publikováno v: Ensho Saisei. 25:525-531

Human neutrophils undergo spontaneous apoptosis, and spontaneous neutrophil apoptosis is delayed in the presence of various inflammatory cytokines, including G-CSF, GM-CSF, IFN-α and IFN-γ. These cytokines exert the antiapoptotic effect on human ne

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6285832e11f2d6dc6bc08602edf33721
https://doi.org/10.2492/jsir.25.525

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Proteolytic Conversion of STAT3α to STAT3γ in Human Neutrophils

Autor: Haruo Kutsuna, Erina Sakamoto, Takayuki Kato, Fumihiko Hato, Seiichi Kitagawa, Akiko Kimura-Eto

Publikováno v: Journal of Biological Chemistry. 279:31076-31080

Four isoforms (alpha, beta, gamma, and delta) have been identified for signal transducer and activator of transcription 3 (STAT3). It has been reported that STAT3gamma, which is derived from STAT3alpha by limited proteolysis during granulocytic diffe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e316bd7bdac070856af0de0e067e2627
https://doi.org/10.1074/jbc.m400637200

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Selective activation of STAT3 in human monocytes stimulated by G-CSF: implication in inhibition of LPS-induced TNF-α production

Autor: Noriko Kamata, Akiko Kimura-Eto, Erina Sakamoto, Taro Hasegawa, Fumihiko Hato, Masayuki Hino, Saori Nishiki, Seiichi Kitagawa

Publikováno v: American Journal of Physiology-Cell Physiology. 286:C1302-C1311

Lipopolysaccharide (LPS) induced tumor necrosis factor (TNF)-α production in human monocytes, which was dependent on activation of extracellular signal-regulated kinase (ERK), p38, c-Jun NH2-terminal kinase (JNK), and nuclear factor (NF)-κB. LPS-in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0a93321937e35cd38d34562df664ce5
https://doi.org/10.1152/ajpcell.00387.2003

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