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pro vyhledávání: '"Erin W. Kavanagh"'
Autor:
Anya T. Joynt, Erin W. Kavanagh, Gregory A. Newby, Shakela Mitchell, Alice C. Eastman, Kathleen C. Paul, Alyssa D. Bowling, Derek L. Osorio, Christian A. Merlo, Shivani U. Patel, Karen S. Raraigh, David R. Liu, Neeraj Sharma, Garry R. Cutting
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 33, Iss , Pp 335-350 (2023)
Canonical splice site variants affecting the 5′ GT and 3′ AG nucleotides of introns result in severe missplicing and account for about 10% of disease-causing genomic alterations. Treatment of such variants has proven challenging due to the unstab
Externí odkaz:
https://doaj.org/article/bc5d8bbde920459b9b6b2f50f6c229eb
Autor:
Erin W. Kavanagh, Jordan J. Green
Publikováno v:
Advanced Healthcare Materials. 11:2102145
Genetic medicine has great potential to treat the underlying causes of many human diseases with exquisite precision, but the field has historically been stymied by delivery as the central challenge. Nanoparticles, engineered constructs the size of na