Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Erin VA"'
Autor:
Erin C. Rooney, Erin VanderJeugdt, Sumant Avasarala, Imtiaz Miah, Matthew J. Berens, Lauren Kinsman-Costello, Michael N. Weintraub, Elizabeth M. Herndon
Publikováno v:
Communications Earth & Environment, Vol 5, Iss 1, Pp 1-9 (2024)
Abstract Permafrost thaw in warming Arctic landscapes alters hydrology and saturation-driven biogeochemical processes. Models assume that aerobic respiration occurs in drained soils while saturated soils support methanogenesis; however, saturated soi
Externí odkaz:
https://doaj.org/article/02e0ca9f11e04df7a849e1c145a7ab61
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Activating transcription factor 4 (ATF4) plays a central role in the integrated stress response (ISR) and one overlapping branch of the unfolded protein response (UPR). We recently reported that the splicing inhibitor isoginkgetin (IGG) indu
Externí odkaz:
https://doaj.org/article/f679efd2f57748fdb7b42e9d9ec0a6f5
Autor:
Bernard Fongang, Claudia Satizabal, Tiffany F. Kautz, Yannick N. Wadop, Jazmyn A. S. Muhammad, Erin Vasquez, Julia Mathews, Monica Gireud-Goss, Amy R. Saklad, Jayandra Himali, Alexa Beiser, Jose E. Cavazos, Michael C. Mahaney, Gladys Maestre, Charles DeCarli, Eric L. Shipp, Ramachandran S. Vasan, Sudha Seshadri
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract A bidirectional communication exists between the brain and the gut, in which the gut microbiota influences cognitive function and vice-versa. Gut dysbiosis has been linked to several diseases, including Alzheimer's disease and related dement
Externí odkaz:
https://doaj.org/article/6cd56d8bd3934f04aeef2cc00faa8818
Publikováno v:
PeerJ, Vol 11, p e16683 (2023)
Background Thapsigargin (Tg) is a compound that inhibits the SERCA calcium transporter leading to decreased endoplasmic reticulum (ER) Ca2+ levels. Many ER chaperones are required for proper folding of membrane-associated and secreted proteins, and t
Externí odkaz:
https://doaj.org/article/a6ace64f6cce496a8a154ec10fac51ba
Publikováno v:
ACR Open Rheumatology, Vol 4, Iss 10, Pp 897-902 (2022)
Background Comparative efficacy randomized controlled trials (RCTs) compare two active interventions in a head‐to‐head design. They are useful for informing clinical practice guidelines, but the degree to which such trials inform clinical practic
Externí odkaz:
https://doaj.org/article/c787e80aaf57419f84fbebe65a6816cc
Publikováno v:
Data in Brief, Vol 42, Iss , Pp 108126- (2022)
Isoginkgetin (IGG) is a compound originally derived from the leaves of Ginkgo biloba trees. It was subsequently identified through a chemical screen to be an inhibitor of both the major and minor spliceosome, with an IC50 value of 30 µM [1]. Little
Externí odkaz:
https://doaj.org/article/5793fca4667249e08ac76f4778abef03
Autor:
Indu Ramachandran, Daniel E. Lowther, Rebecca Dryer-Minnerly, Ruoxi Wang, Svetlana Fayngerts, Daniel Nunez, Gareth Betts, Natalie Bath, Alex J. Tipping, Luca Melchiori, Jean-Marc Navenot, John Glod, Crystal L. Mackall, Sandra P. D’Angelo, Dejka M. Araujo, Warren A. Chow, George D. Demetri, Mihaela Druta, Brian A. Van Tine, Stephan A. Grupp, Albiruni R. Abdul Razak, Breelyn Wilky, Malini Iyengar, Trupti Trivedi, Erin Van Winkle, Karen Chagin, Rafael Amado, Gwendolyn K. Binder, Samik Basu
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-14 (2019)
Abstract Background Gene-modified autologous T cells expressing NY-ESO-1c259, an affinity-enhanced T-cell receptor (TCR) reactive against the NY-ESO-1-specific HLA-A*02-restricted peptide SLLMWITQC (NY-ESO-1 SPEAR T-cells; GSK 794), have demonstrated
Externí odkaz:
https://doaj.org/article/08dda14b5f1b4ef08600740b083a4b11
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
Excess dietary fructose is a major public health concern (1–4). Evidence shows increased fructose intake can cause insulin resistance, hepatic de novo lipogenesis, hypertriglyceridemia, obesity and non-alcoholic fatty liver disease (NAFLD) (5–9).
Externí odkaz:
https://doaj.org/article/f03cc5845acc462bbf4e21f2039eefcc
Publikováno v:
Frontiers in Neurology, Vol 10 (2019)
Background: Convergence insufficiency (CI) in parkinsonian conditions causes disabling visual symptoms during near tasks and usually manifests as double vision. Since double vision is more common in patients who report cognitive symptoms, we sought t
Externí odkaz:
https://doaj.org/article/5b8401e729914de288298aa5f106db08
Autor:
Ilene Berger Morris, Erin Vasudevan, Margaret Schedel, Daniel Weymouth, Jay Loomis, Tzvia Pinkhasov, Lisa M. Muratori
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Parkinson’s disease (PD) is a complex diagnosis commonly associated with motor dysfunction, but known to comprise cognitive, psychiatric, and mood disturbances as well. Music has been successfully used to address motor and non-motor symptoms of PD.
Externí odkaz:
https://doaj.org/article/ca8fba7872e24ebf8aeff02f08353f06