Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Erin V. Shea"'
Autor:
Erin V. Shea, Natalie L. Sinicropi, Matthew F. Cusick, Raja Rabah, Heang M. Lim, Kurt R. Schumacher, Amanda D. McCormick, David M. Peng
Publikováno v:
Transplantation Proceedings.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::128064afeb16fa72a82fdf09f38d638c
https://doi.org/10.1016/j.transproceed.2023.04.021
https://doi.org/10.1016/j.transproceed.2023.04.021
Autor:
Matthew Pratt-Hyatt, Haoming Zhang, Cesar Kenaan, Erin V. Shea, Hsia Lien Lin, Paul F. Hollenberg
Publikováno v:
Drug Metabolism and Disposition. 41:101-110
Studies in microsomal and reconstituted systems have shown that the presence of one cytochrome P450 isoform can significantly influence the catalytic activity of another isoform. In this study, we assessed whether CYP2E1 could influence the catalytic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d2a06797eca9a30d2d228a744f839b8
https://doi.org/10.1124/dmd.112.046094
https://doi.org/10.1124/dmd.112.046094
Publikováno v:
Biochemistry. 50:3957-3967
Cytochrome P450 (CYP or P450)-mediated drug metabolism requires the interaction of P450s with their redox partner, cytochrome P450 reductase (CPR). In this work, we have investigated the role of P450 hydrophobic residues in complex formation with CPR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::140071b50af503ce67b413b1fefec734
https://doi.org/10.1021/bi1020748
https://doi.org/10.1021/bi1020748