Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Erin V. McConnell"'
Autor:
Jane Xu Kelly, Rozalia A. Dodean, Papireddy Kancharla, Erin V. McConnell, Jan M. Boitz Zarella, J. Stone Doggett, P. Holland Alday
Publikováno v:
ACS Infectious Diseases. 7:1877-1884
Acridone derivatives, which have been shown to have in vitro and in vivo activity against Plasmodium spp, inhibit Toxoplasma gondii proliferation at picomolar concentrations. Using enzymatic assays, we show that acridones inhibit both T. gondii cytoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cdc7aa68b816b960c6000495d3958c3e
https://doi.org/10.1021/acsinfecdis.1c00016
https://doi.org/10.1021/acsinfecdis.1c00016
Autor:
P Holland, Alday, Erin V, McConnell, Jan M, Boitz Zarella, Rozalia A, Dodean, Papireddy, Kancharla, Jane X, Kelly, J Stone, Doggett
Publikováno v:
ACS Infect Dis
Acridone derivatives, which have been shown to have in vitro and in vivo activity against Plasmodium spp, inhibit Toxoplasma gondii proliferation at picomolar concentrations. Using enzymatic assays, we show that acridones inhibit both T. gondii cytoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::965472a1a703b6539d887f1203a53ac3
https://pubmed.ncbi.nlm.nih.gov/33723998
https://pubmed.ncbi.nlm.nih.gov/33723998
Autor:
Kayode K. Ojo, Molly C. McCloskey, Igor Bruzual, Suzanne Scheele, Amy E. DeRocher, Samuel L.M. Arnold, J. Stone Doggett, Grant R. Whitman, Erkang Fan, Marilyn Parsons, Wenlin Huang, Kasey Rivas, Erin V. McConnell, Rama Subba Rao Vidadala, Ryan Choi, Matthew A. Hulverson, Wesley C. Van Voorhis, Lynn K. Barrett, Dustin J. Maly
Publikováno v:
The Journal of Infectious Diseases. 219:1464-1473
Bumped kinase inhibitors (BKIs) have been shown to be potent inhibitors of Toxoplasma gondii calcium-dependent protein kinase 1. Pyrazolopyrimidine and 5-aminopyrazole-4-carboxamide scaffold-based BKIs are effective in acute and chronic experimental
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de34a52937ca4105d7dea738d41fc84e
https://doi.org/10.1093/infdis/jiy664
https://doi.org/10.1093/infdis/jiy664
Autor:
J. Stone Doggett, Sovitj Pou, Michael K. Riscoe, Igor Bruzual, Alina Krollenbrock, Aaron Nilsen, Rolf W. Winter, Erin V. McConnell, Martin J. Smilkstein, Rozalia Dodean, Lev N. Zakharov
Publikováno v:
ACS Infectious Diseases. 4:1574-1584
Cytochrome bc1 inhibitors have been broadly studied as human and veterinary medicines and agricultural fungicides. For the most part, cytochrome bc1 inhibitors compete with ubiquinol at the ubiquinol oxidation (Qo) site or with ubiquinone at the quin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::caee187972389022baf5702049a19620
https://doi.org/10.1021/acsinfecdis.8b00133
https://doi.org/10.1021/acsinfecdis.8b00133